5,127 research outputs found
Analysis of complete positivity conditions for quantum qutrit channels
We present an analysis of complete positivity (CP) constraints on qutrit
quantum channels that have a form of affine transformations of generalized
Bloch vector. For diagonal (damping) channels we derive conditions analogous to
the ones that in qubit case produce tetrahedron structure in the channel
parameter space.Comment: 12 pages, 8 figures (.eps), minor changes in the text and formula
Gas Absorption Detected from the Edge-on Debris Disk Surrounding HD32297
Near-infrared and optical imaging of HD32297 indicate that it has an edge-on
debris disk, similar to beta Pic. I present high resolution optical spectra of
the NaI doublet toward HD32297 and stars in close angular proximity. A
circumstellar absorption component is clearly observed toward HD32297 at the
stellar radial velocity, which is not observed toward any of its neighbors,
including the nearest only 0.9 arcmin away. An interstellar component is
detected in all stars >90 pc, including HD32297, likely due to the interstellar
material at the boundary of the Local Bubble. Radial velocity measurements of
the nearest neighbors, BD+07 777s and BD+07 778, indicate that they are
unlikely to be physically associated with HD32297. The measured circumstellar
column density around HD32997, log N(NaI) ~ 11.4, is the strongest NaI
absorption measured toward any nearby main sequence debris disk, even the
prototypical edge-on debris disk, beta Pic. Assuming that the morphology and
abundances of the gas component around HD32297 are similar to beta Pic, I
estimate an upper limit to the gas mass in the circumstellar disk surrounding
HD32297 of ~0.3 M_Earth.Comment: 13 pages, 2 figures; Accepted for publication in ApJ Letter
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells - Activation of protein kinase B by wortmannin-sensitive and -insensittve mechanisms
Previous studies using L6 myotubes have suggested that glycogen synthase kinase-3 (GSK-3) is phosphoryl ated and inactivated in response to insulin by protein kinase B (PKB, also known as Akt or RAG) (Cross, D, A, E., Alessi, D, R., Cohen, P., Andjelkovic, M., and Hemmings, B, A. (1995) Nature 378, 785-789), In the present study, marked increases in the activity of PKB have been shown to occur in insulin-treated rat epididymal fat cells with a time course compatible with the observed decrease in GSK-3 activity, Isoproterenol, acting primarily through beta(3)-adrenoreceptors, was found to decrease GSK-3 activity to a similar extent (approximately 50%) to insulin, However, unlike the effect of insulin, the inhibition of GSK by isoproterenol was not found to be sensitive to inhibition by the phosphatidylinositol 3'-kinase inhibitors, wortmannin or LY 294002, The change in GSK-3 activity brought about by isoproterenol could not be mimicked by the addition of permeant cyclic AMP analogues or forskolin to the cells, although at the concentrations used, these agents were able to stimulate lipolysis. Isoproterenol, but again not the cyclic AMP analogues, was found to increase the activity of PKB, although to a lesser extent than insulin. While wortmannin abolished the stimulation of PKB activity by insulin, it was without effect on the activation seen in response to isoproterenol, The activation of PKB by isoproterenol was not accompanied by any detectable change in the electrophoretic mobility of the protein on SDS-polyacrylamide gel electrophoresis. It would therefore appear that distinct mechanisms exist for the stimulation of PKB by insulin and isoproterenol in rat fat cells
Discovery of 15-second oscillations in Hubble Space Telescope observations of WZ Sagittae following the 2001 outburst
We report the discovery of 15-s oscillations in ultraviolet observations of
WZ Sge obtained with the Hubble Space Telescope approximately one month after
the peak of the 2001 outburst. This is the earliest detection of oscillations
in WZ Sge following an outburst and the first time that a signal near 15 s has
been seen to be dominant. The oscillations are quite strong (amplitude about
5%), but not particularly coherent. In one instance, the oscillation period
changed by 0.7 s between successive observations separated by less than 1 hour.
We have also found evidence for weaker signals with periods near 6.5 s in some
of our data. We discuss the implications of our results for the models that
have been proposed to account for the 28-s oscillations seen in quiescence. If
the periods of the 15-s oscillations can be identified with the periods of
revolution of material rotating about the white dwarf, the mass of the white
dwarf must satisfy M_WD > 0.71 M_sun. The corresponding limit for the 6.5-s
signals is M_WD > 1.03 M_sun.Comment: accepted for publication in ApJ Letters; 13 pages, 4 postscript
figures; new version corrects a few typos and matches version that will
appear in ApJ
Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p>
<p><b>Methods and Results:</b> In the PROSPER (PROspective Study of Pravastatin in the Elderly at Risk) cohort, we related baseline concentrations of circulating IL-10 to risk of CVD events in a nested case (n=819)-control (n=1618) study of 3.2 years of follow-up. Circulating IL-10 showed few strong associations with classical risk factors but was positively correlated with IL-6 and C-reactive protein. IL-10 was positively associated with risk of CVD events (odds ratio [OR] 1.17, 95% CI 1.05 to 1.31 per unit increase in log IL-10) after adjusting for classical risk factors and C-reactive protein. Furthermore, IL-10 was associated more strongly with CVD risk among those with no previous history of CVD (OR 1.42, 95% CI 1.18 to 1.70), compared with those with previous CVD (OR 1.04, 95% CI 0.90 to 1.19; P=0.018). Overall, IL-10 showed a modest ability to add discrimination to classical risk factors (C-statistic +0.005, P=0.002).</p>
<p><b>Conclusion:</b> Baseline circulating levels of the antiinflammatory IL-10 are positively associated with risk of CVD among the elderly without prior CVD events, although the association is less evident in those with a history of CVD. Additional epidemiological and mechanistic studies investigating the role of IL-10 in CVD are warranted.</p>
A Tool for Developing Correct Programs by Refinement
This report reviews the requirements for tool support of refinement, and reports on the design and implementation of a new tool to support refinement based on these requirements. The main features of the new tool are close integration of refinement and proof in a single tool, good management of the refinement context, an extensible theory base that allows the tool to be adapted to new application domains, and a flexible user interface
Simultaneous EUV and X-ray variability of NGC 4051
We present a flux variability study of simultaneous RXTE and EUVE
observations of the highly variable Seyfert galaxy NGC4051. We find a strong
correlation between variability in the EUV and medium energy X-ray
bands,indicating that both are sampling the same power-law continuum. The lag
between the two bands is less than 20 ks and, depending on model assumptions,
may be <1 ks. We examine the consequences of such a small lag in the context of
simple Comptonisation models for the production of the power-law continuum. A
lag of <1 ks implies that the size of the Comptonising region is less than 20
Schwarzschild radii for a black hole of mass >1E6 solar masses.Comment: 8 pages, accepted for publication in MNRA
On the accretion disc properties in eclipsing dwarf nova EM Cyg
In this paper we analyzed the behavior of the unusual dwarf nova EM Cyg using
the data obtained in April-October, 2007 in Vyhorlat observatory (Slovak
Republic) and in September, 2006 in Crimean Astrophysical Observatory
(Ukraine). During our observations EM Cyg has shown outbursts in every 15-40
days. Because on the light curves of EM Cyg the partial eclipse of an accretion
disc is observed we applied the eclipse mapping technique to reconstruct the
temperature distribution in eclipsed parts of the disc. Calculations of the
accretion rate in the system were made for the quiescent and the outburst
states of activity for different distances.Comment: 6 pages, 3 figures, accepted in Astrophysics and Space Scienc
Future U.S. supply of Mo-99 production through fission based LEU/LEU technology
Coquí RadioPharmaceuticals Corp. (Coquí) has the goal of establishing a medical isotope production facility for securing a continuous domestic supply of the radioisotope molybdenum-99 for U.S. citizens. Coquí will use an LEU/LEU proven and implemented open pool, light-water, 10 MW, reactor design. The facility is being designed with twin reactors for reliability an on-site hot lab chemical processing and a waste conditioning area and a possible generator producing radio-chemistry lab. Coquí identified a 25 acre site adjacent to an existing industrial park in northern central Florida. This land was gifted and transferred to Coquí by the University of Florida Foundation. We are in the process of developing licensing documents related to the facility. The construction permit application for submission to the U.S. Nuclear Regulatory Commission is currently being prepared. Submission is scheduled for mid to late 2015. Community reaction to the proposed development has been positive. We expect to create 220 permanent jobs and we have an anticipated to be operational by 2020
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