Accelerated and Synchronized Oviposition Induced by Flight of Young Females May Intensify Larval Outbreaks of the Rice Leaf Roller

Physiological management of migration-reproduction trade-offs in energy allocation often includes a package of adaptions referred to as the oogenesis-flight syndrome. In some species, this trade-off may be overestimated, because factors like flight behavior and environmental conditions may mitigate it. In this study, we examined the reproductive consequences induced by different flight scenarios in an economically-important Asian migrant insect, Cnaphalocrocis medinalis. We found that the influences of flight on reproduction are not absolutely positive or negative, but instead depend on the age at which the moth begins flight, flight duration, and how many consecutive nights they are flown. Adult flight on the 1st or 2nd night after emergence, flight for 6 h or 12 h nightly, and flight on the first two consecutive nights after emergence significantly accelerated onset of oviposition or enhanced synchrony of egg-laying. The latter can contribute to subsequent larval outbreaks. However, flight after the 3rd night, flight for 18 h at any age, or flight on more than 3 consecutive nights after adult emergence did not promote reproductive development, and in some scenarios even constrained adult reproduction. These results indicate that there is a migration/reproduction trade-off in C.medinalis, but that it is mitigated or eliminated by flight under appropriate conditions. The strategy of advanced and synchronized oviposition triggered by migratory flight of young females may be common in other migratory insect pests

Opportunities and challenges for Chinese elderly care industry in smart environment based on occupants' needs and preferences

New developments in intelligent devices for assisting elderly people can provide elders with friendly, mutual, and personalized interactions. Since the intelligent devices should continually make an important contribution to the smart elderly care industry, smart services or policies for the elders are recently provided by a large number of government programs in China. At present, the smart elderly care industry in China has attracted numerous investors’ attention, but the smart elderly care industry in China is still at the beginning stage. Though there are great opportunities in the market, many challenges and limitations still need to be solved. This study analyzes 198 news reports about opportunities and challenges in the smart elderly care industry from six major Chinese portals. The analysis is mainly based on needs assessment for elderly people, service providers, and the Chinese government. It is concluded that smart elderly care services satisfy the elders’ mental wants and that needs for improving modernization services are the most frequently mentioned opportunities. Also, the frequently mentioned challenges behind opportunities are intelligent products not being able to solve the just-needed, user-consumption concept and the ability to pay, which is the most frequently mentioned challenge. The results of this study will enable stakeholders in the smart elderly care industry to clarify the opportunities and challenges faced by smart elderly care services in China’s development process and provide a theoretical basis for better decision making

Antenatal depression is associated with perceived stress, family relations, educational and professional status among women in South of China: a multicenter cross-sectional survey

BackgroundAntenatal depression is a commonly seen mental health concern for women. This study introduced a multicenter cross-sectional survey with a large sample to provide new insights into pregnant women’s depression, its socio-demographic and obstetric characteristics correlates, and its perceived stress among Chinese pregnant women.MethodsThis study conducted an observational survey according to the STROBE checklist. The multicenter cross-sectional survey was performed from August 2020 to January 2021 by distributing paper questionnaires among pregnant women from five tertiary hospitals in South China. The questionnaire included socio-demographic and obstetrics information, the Edinburgh Postnatal Depression Scale, and the 10-item Perceived Stress Scale. For the analyses, the Chi-square test and Multivariate logistic regression were utilized.ResultsAmong 2014 pregnant women in their second/third trimester, the prevalence of antenatal depression was 36.3%. 34.4% of pregnant women reported AD in their second trimester of pregnancy, and 36.9% suffered from AD in third trimester of pregnancy. A multivariate logistic regression model indicated that unemployed women, lower levels of education, poor marital relationships, poor parents-in-law relationships, concerns about contracting COVID-19, and higher perceived stress could aggravate antenatal depression among participants (p<0.05).ConclusionThere is a high proportion of antenatal depression among pregnant women in South China, so integrating depression screening into antenatal care services is worthwhile. Maternal and child health care providers need to evaluate pregnancy-related risk factors (perceived stress), socio-demographic factors (educational and professional status), and interpersonal risk factors (marital relations and relationship with Parents-in-law). In future research, the study also emphasized the importance of providing action and practical support to reduce the experience of antenatal depression among disadvantaged sub-groups of pregnant women

Anxiety, depression, and insomnia among nurses during the full liberalization of COVID-19: a multicenter cross-sectional analysis of the high-income region in China

IntroductionFrontline nurses fighting against the epidemic were under great psychological stress. However, there is a lack of studies assessing the prevalence rates of anxiety, depression, and insomnia among frontline nurses after the full liberalization of COVID-19 in China. This study demonstrates the impact of the full liberalization of COVID-19 on the psychological issues and the prevalence rate and associated factors of depressive symptoms, anxiety, and insomnia among frontline nurses.MethodsA total of 1766 frontline nurses completed a self-reported online questionnaire by convenience sampling. The survey included six main sections: the 9-item Patient Health Questionnaire (PHQ-9), the 7-item Generalized Anxiety Disorder (GAD-7), the 7-item Insomnia Severity Index (ISI), the 10-item Perceived Stress Scale (PSS-10), sociodemographic information, and work information. Multiple logistic regression analyses were applied to identify the potential significantly associated factors for psychological issues. The study methods were compliant with the STROBE checklist.Results90.83% of frontline nurses were infected with COVID-19, and 33.64% had to work while infected COVID-19. The overall prevalence of depressive symptoms, anxiety and insomnia among frontline nurses was 69.20%, 62.51%, and 76.78%, respectively. Multiple logistic analyses revealed that job satisfaction, attitude toward the current pandemic management, and perceived stress were associated with depressive symptoms, anxiety, and insomnia.ConclusionsThis study highlighted that frontline nurses were suffering from varying degrees of depressive symptoms, anxiety, and insomnia during full liberalization of COVID-19. Early detection of mental health issues and preventive and promotive interventions should be implemented according to the associated factors to prevent a more serious psychological impact on frontline nurses

Alcohol Exposure Decreases CREB Binding Protein Expression and Histone Acetylation in the Developing Cerebellum

Fetal alcohol exposure affects 1 in 100 children making it the leading cause of mental retardation in the US. It has long been known that alcohol affects cerebellum development and function. However, the underlying molecular mechanism is unclear.We demonstrate that CREB binding protein (CBP) is widely expressed in granule and Purkinje neurons of the developing cerebellar cortex of naïve rats. We also show that exposure to ethanol during the 3(rd) trimester-equivalent of human pregnancy reduces CBP levels. CBP is a histone acetyltransferase, a component of the epigenetic mechanism controlling neuronal gene expression. We further demonstrate that the acetylation of both histone H3 and H4 is reduced in the cerebellum of ethanol-treated rats.These findings indicate that ethanol exposure decreases the expression and function of CBP in the developing cerebellum. This effect of ethanol may be responsible for the motor coordination deficits that characterize fetal alcohol spectrum disorders

Fragile X Mental Retardation Protein Regulates Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells

Fragile X syndrome (FXS), the most common form of inherited mental retardation, is caused by the loss of functional fragile X mental retardation protein (FMRP). FMRP is an RNA–binding protein that can regulate the translation of specific mRNAs. Adult neurogenesis, a process considered important for neuroplasticity and memory, is regulated at multiple molecular levels. In this study, we investigated whether Fmrp deficiency affects adult neurogenesis. We show that in a mouse model of fragile X syndrome, adult neurogenesis is indeed altered. The loss of Fmrp increases the proliferation and alters the fate specification of adult neural progenitor/stem cells (aNPCs). We demonstrate that Fmrp regulates the protein expression of several components critical for aNPC function, including CDK4 and GSK3β. Dysregulation of GSK3β led to reduced Wnt signaling pathway activity, which altered the expression of neurogenin1 and the fate specification of aNPCs. These data unveil a novel regulatory role for Fmrp and translational regulation in adult neurogenesis

Electric Vehicle Charging Load Prediction Model Considering Traffic Conditions and Temperature

The paper presents a novel charging load prediction model for electric vehicles that takes into account traffic conditions and ambient temperature, which are often overlooked in conventional EV load prediction models. Additionally, the paper investigates the impact of disordered charging on distribution networks. Firstly, the paper creates a traffic road network topology and speed-flow model to accurately simulate the driving status of EVs on real road networks. Next, we calculate the electric vehicle power consumption per unit kilometer by considering the effects of temperature and vehicle speed on electricity consumption. Then, we combine the vehicle’s main parameters to create a single electric vehicle charging model, use the Monte Carlo method to simulate electric vehicle travel behavior and charging, and obtain the spatial and temporal distribution of total charging load. Finally, the actual traffic road network and typical distribution network in northern China are used to analyze charging load forecast estimates for each typical functional area under real vehicle–road circumstances. The results show that the charging load demand in different areas has obvious spatial and temporal distribution characteristics and differences, and traffic conditions and temperature factors have a significant impact on electric vehicle charging load

Investigation of flow instability characteristics in a low specific speed centrifugal pump using a modified partially averaged Navier-Stokes model

In this study, a modified partially averaged Navier-Stokes (MPANS) model is applied to investigate the flow instability characteristics in a low specific centrifugal pump. In MPANS model, the unresolved-to-total ratio of kinetic energy f(k) is determined according to the local grid size and turbulence length scale. The numerical results by MPANS model are compared with that simulated by SST k-omega model and the available experimental data. It is noted that MPANS model shows better performance for investigating the unstable flow in the current pump under part-load operation conditions. The time-averaged internal flow and flow incidence in the pump impeller depicts that with the decreasing flow coefficient, flow separation develops in the impeller. Owing to the strong separation flow as well as vortex evolution, incidence angle is large and varies remarkably at the entrance of blade-to-blade passage in the pump impeller. The evolution dynamics of rotating stall is further discussed in detail based on vorticity transport equation. During the evolution of rotating stall, the vortex stretching term has an important effect on vorticity transport under the part-load conditions. The analysis of the pressure fluctuations excited by periodic evolution of rotating stall shows that the rotating stall cell propagates along the rotational direction, and identifies the rotating stall frequency (f(stall)), which is much lower than the rotational frequency of the impeller, f(n) (f(stall) = 8.76% f(n)). Finally, two-dimensional Lagrangian coherent structure (LCS) is used to reveal the separation flow in blade-to-blade passages of the pump by monitoring the trajectory of the particles. Both LCS and vortex structure by lambda(2) can clearly demonstrates the passage blockage and flow separation under the part-load operation conditions, depicting that the separation flow occurs at blade suction side and develops from the leading edge to the main passage in the impeller

Instability analysis under part-load conditions in centrifugal pump

In this study, a centrifugal pump with a specific speed of 39.12 mxmin(-1)xm(3)s(-1) is treated to analyze the flow instability under part-load conditions by numerical simulation and experimental test. For calculations, the RANS method, coupled with the k- SST turbulence model, is adopted. Numerical results at different operation points are compared with available experimental data, such as hydraulic performance and flow field information by particle image velocimetry. The numerical and experiment results agree well. The flow simulation indicates a strong reverse flow at the passage upstream impeller inlet, and the energy loss in the impeller is the largest under part-load conditions among all flow components in the pump. In one impeller revolution, one blade-to-blade flow passage is always nearly blocked off by the rotating stall occurring at the impeller inlet for each instant, and the blockage induces a jet flow with large velocity at the next blade-to-blade flow passage along the rotational direction of the impeller. The blockage and the jet flow in the blade-to-blade flow passages will make the flow unstable inside the impeller and cause performance breakdown and pressure vibration under part-load conditions for the pump