Health related Quality of Life over time in German sarcoma patients. An analysis of associated factors - results of the PROSa study

Introduction Sarcomas are rare cancers and very heterogeneous in their location, histological subtype, and treatment. Health-Related Quality of Life (HRQoL) of sarcoma patients has rarely been investigated in longitudinal studies. Methods Here, we assessed adult sarcoma patients and survivors between September 2017 and February 2020, and followed-up for one year in 39 study centers in Germany. Follow-up time points were 6 (t1) and 12 months (t2) after inclusion. We used a standardized, validated questionnaire (the European Organisation for Research and Treatment of Cancer Quality of Life Core Instrument (EORTC QLQ-C30) and explored predictors of HRQoL in two populations (all patients (Analysis 1), patients in ongoing complete remission (Analysis 2)) using generalized linear mixed models. Results In total we included up to 1111 patients at baseline (915 at t1, and 847 at t2), thereof 387 participants were in complete remission at baseline (334 at t1, and 200 at t2). When analyzing all patients, HRQoL differed with regard to tumor locations: patients with sarcoma in lower extremities reported lower HRQoL values than patients with sarcomas in the upper extremities. Treatment which included radiotherapy and/or systemic therapy was associated with lower HRQoL. For patients in complete remission, smoking was associated with worse HRQoL-outcomes. In both analyses, bone sarcomas were associated with the worst HRQoL values. Being female, in the age group 55-&lt;65 years, having lower socioeconomic status, and comorbidities were all associated with a lower HRQoL, in both analyses. Discussion HRQoL increased partially over time since treatment and with sporting activities. HRQoL improved with time since treatment, although not in all domains, and was associated with lifestyle and socioeconomic factors. Bone sarcomas were the most affected subgroup. Methods to preserve and improve HRQoL should be developed for sarcoma patients. </sec

Ökonomische Bildung im Rahmen politischer Bildung. Das Kerncurriculum "Ökonomische Bildung als integrativer Teil der politischen Bildung"

Hedtke R. Ökonomische Bildung im Rahmen politischer Bildung. Das Kerncurriculum "Ökonomische Bildung als integrativer Teil der politischen Bildung". In: Weitz B, ed. Standards der ökonomischen Bildung. Wirtschafts- und berufspädagogische Schriften. Vol 32. Bergisch Gladbach: Hobein; 2005: 77-110

The Searchbench - Combining Sentence-semantic, Full-text and Bibliographic Search in Digital Libraries

We describe a novel approach to precise searching in the full content of digital libraries. The Searchbench (for search workbench) is based on sentence-wise syntactic and semantic natural language processing (NLP) of both born-digital and scanned publications in PDF format. The term born-digital means natively digital, i.e. prepared electronically using typesetting systems such as LaTeX, OpenOffice, and the like. In the Searchbench, queries can be formulated as (possibly underspecified) statements, consisting of simple subject-predicate-object constructs such as ‘algorithm improves word alignment’. This reduces the number of false hits in large document collections when the search words happen to appear close to each other, but are not semantically related. The method also abstracts from passive voice and predicate synonyms. Moreover, negated statements can be excluded from the search results, and negated antonym predicates again count as synonyms (e.g. not include = exclude).In the Searchbench, a sentence-semantic search can be combined with search filters for classical full-text, bibliographic metadata and automatically computed domain terms. Auto-suggest fields facilitate text input. Queries can be bookmarked or emailed. Furthermore, a novel citation browser in the Searchbench allows graphical navigation in citation networks. These have been extracted automatically from metadata and paper texts. The citation browser displays short phrases from citation sentences at the edges in the citation graph and thus allows students and researchers to quickly browse publications and immerse into a new research field. By clicking on a citation edge, the original citation sentence is shown in context, and optionally also in the original PDF layout.To showcase the usefulness of our research, we have a applied it to a collection of currently approx. 25,000 open access research papers in the field of computational linguistics and language technology, the ACL Anthology ( http://aclweb.org/anthology). The Searchbench user interface is a web application running in every modern, JavaScript-enabled web browser, also on smart phones and tablet computers. The system is a free and public service at http://aclasb.dfki.de. Because the NLP technology is domain-independent, it could also be applied to newspaper texts, technical documentation, or scientific publications from other disciplines. The aim of this paper is to make the benefits of this new, language technology based approach known in library research and related fields.This article summarises 9 peer reviewed publications from the past three years that have been published in international conferences and workshops in the area of computational linguistics, and tries to present them in an appropriate way to the LIBER audience. The original papers contain more details and are freely available from the author’s homepage[1] or via the Searchbench[2]

The Searchbench - Combining Sentence-semantic, Full-text and Bibliographic Search in Digital Libraries

We describe a novel approach to precise searching in the full content of digital libraries. The Searchbench (for search workbench) is based on sentence-wise syntactic and semantic natural language processing (NLP) of both born-digital and scanned publications in PDF format. The term born-digital means natively digital, i.e. prepared electronically using typesetting systems such as LaTeX, OpenOffice, and the like. In the Searchbench, queries can be formulated as (possibly underspecified) statements, consisting of simple subject-predicate-object constructs such as ‘algorithm improves word alignment’. This reduces the number of false hits in large document collections when the search words happen to appear close to each other, but are not semantically related. The method also abstracts from passive voice and predicate synonyms. Moreover, negated statements can be excluded from the search results, and negated antonym predicates again count as synonyms (e.g. not include = exclude).In the Searchbench, a sentence-semantic search can be combined with search filters for classical full-text, bibliographic metadata and automatically computed domain terms. Auto-suggest fields facilitate text input. Queries can be bookmarked or emailed. Furthermore, a novel citation browser in the Searchbench allows graphical navigation in citation networks. These have been extracted automatically from metadata and paper texts. The citation browser displays short phrases from citation sentences at the edges in the citation graph and thus allows students and researchers to quickly browse publications and immerse into a new research field. By clicking on a citation edge, the original citation sentence is shown in context, and optionally also in the original PDF layout.To showcase the usefulness of our research, we have a applied it to a collection of currently approx. 25,000 open access research papers in the field of computational linguistics and language technology, the ACL Anthology ( http://aclweb.org/anthology). The Searchbench user interface is a web application running in every modern, JavaScript-enabled web browser, also on smart phones and tablet computers. The system is a free and public service at http://aclasb.dfki.de. Because the NLP technology is domain-independent, it could also be applied to newspaper texts, technical documentation, or scientific publications from other disciplines. The aim of this paper is to make the benefits of this new, language technology based approach known in library research and related fields.This article summarises 9 peer reviewed publications from the past three years that have been published in international conferences and workshops in the area of computational linguistics, and tries to present them in an appropriate way to the LIBER audience. The original papers contain more details and are freely available from the author’s homepage[1] or via the Searchbench[2]

Dritter Bericht der wissenschaftlichen Begleitung zum Modellversuch Lernbuero neue Informationstechnologien und Datenverarbeitung im Berufsfeld Wirtschaft und Verwaltung ; Verbindung von berufspraktischer und theoretischer Arbeit (Ausbildung) im Lernbuero

UuStB Koeln(38)-890106153 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman