Nuclear spectroscopy of 60Ni

High-spin states in 6060Ni were populated using the 28Si(36Ar,4p) reaction with a beam energy of 136 MeV. GAMMASPHERE was used in conjunction with MICROBALL to detect γ rays in coincidence with various combinations of detected protons and alphas. A total of 2 billion events was recorded, with the 4p channel to 60Ni representing approximately 11 % of the data. In our analysis, the previously known level scheme[1] has been extended up to energy and spin of 20 MeV and 19 ħ. The levels up to/ = 10 is well explained by shell-model calculations including the g9/2 single-particle orbital in the f p-shell configuration space. At higher spins, evidence for rotational-like behavior appears. Two apparently rotational structures have large M1 values and are perhaps shears bands, likely involving one g9/2 particle. Comparison to calculations will be given

Inside the Economist's Mind: The History of Modern Economic Thought, as Explained by Those Who Produced It

This is the front matter from a book of interviews to be published by Blackwell. The book is coedited by W. A. Barnett and P. A. Samuelson. The front matter includes the Table of Contents, Coeditor Preface by W. A. Barnett, Coeditor Foreword by Paul A. Samuelson, and History of Thought Introduction by E. Roy Weintraub. The front matter highlights some of the more startling and controversial statements contained in the interviews and puts the interviews into context relative to the history of modern economic thought. The interviews reprinted in this book include: (1) Wassily Leontief interviewed by Duncan Foley. (2) David Cass interviewed jointly by Steven Spear and Randall Wright. (3) Robert E. Lucas interviewed by Bennett T. McCallum. (4) Janos Kornai interviewed by Olivier Blanchard. (5) Franco Modigliani interviewed by William Barnett and Robert Solow. (6) Milton Friedman interviewed by John Taylor. (7) Paul A. Samuelson interviewed by William A. Barnett. (8) Paul Volcker interviewed by Perry Mehrling. (9) Martin Feldstein interviewed by James Poterba. (10) Christopher Sims interviewed by Lars Peter Hansen. (11) Robert Shiller interviewed by John Campbell. (12) Stanley Fischer interviewed by Olivier Blanchard. (13) Jacques Drèze interviewed by Pierre Dehez and Omar Licandro. (14) Tom Sargent interviewed by George Evans and Seppo Honkapohja. (15) Robert Aumann interviewed by Sergiu Hart. (16) James Tobin and Robert Shiller interviewed by David Colander.history of economic thought, Samuelson, macroeconomics, microeconomics, policy, interviews

Interventional cardiology : Cost-effectiveness of PCI guided by fractional flow reserve

Coronary revascularization strategies have been evaluated in numerous clinical trials. As coronary revascularization has become more common, concerns over financial costs have increased

Can restenosis after coronary angioplasty be predicted from clinical variables?

AbstractObjectives. The purpose of this study was to determine whether variables shown to correlate with restenosis in one group (learning group) could be shown to predict recurrent stenosis in a second group (validation group).Background. Restenosis remains a critical limitation after percutaneous transluminal coronary angioplasty. Although several clinical variables have been shown to correlate with restenosis, there are few data concerning attempts to predict recurrent stenosis.Methods. The source of data was the clinical data bese at Emory University. Patients who had had previous coronary surgery and patients who underwent coronary angioplasty in the setting of acute myocardial Infarction were excluded. A total of 4,006 patients with angiographic restudy after successful angioplisty were identified. They were classified into a learning group of 2,500 patients and a validation group of 1,506 patients. The correlates of restenosis in the learning group were determined by stepwise logistic regression, and a model was developed to predict the probability of restenosis and was tested in the validation group. By using various cut points for the predicted probability of restenosis, a receiver operating characteristic curve was created. Goodness of fit of the model was evaluated by comparing average predicted probabilities with average observed probabilities within subgroups on the basis of risk level determined by linear regression analysis.Results. In the learning group 1,145 patients had restenosis and 1,355 did not. Correlates of restenosis were severe angina, severe diameter stenosis before angioplasty, left anterior descending coronary artery dilation, diabetes, greater diameter stenosis after angioplasty, hypertension, absence of an intimal tear, eccentric morphology and older patient age. The model derived from the learing group was used to predict restenosis in the validation group. By varying the cut point for the predicted probability of restenosis above which restenosis is diagnosed and below which it is not, a receiver operating characteristic curve was created. The curve was close to the line of identity, reflecting a poor predictive ability. However, the model was shown to fit well with the predicted probability of restenosis correlating well with the observed probability (r = 0.98, p = 0.0001).Conclusions. Clinical variables provide limited ability to predict definitively whether a particular patient will have restenosis. However, the current model may be used to predict the probability of restenosis, with some uncertainty, at least in well characterized patients who have already had angioplasy

Cost-Effectiveness of Eplerenone in Patients with Left Ventricular Dysfunction after Myocardial Infarction—An Analysis of the EPHESUS Study from a Swiss Perspective

Objective: The EPHESUS study demonstrated that aldosterone blockade with eplerenone decreased mortality in patients with left ventricular systolic dysfunction (LVSD) and heart failure after acute myocardial infarction (AMI). The EPHESUS pharmacoeconomic analysis was performed to evaluate the cost-effectiveness of eplerenone in the Swiss setting. Materials and methods: A total of 6,632 patients with LVSD and heart failure after AMI were randomized to eplerenone or placebo and followed for a mean of 16months. The co-primary endpoints were all-cause death and the composite of cardiovascular death/cardiovascular hospitalization. The evaluation of resource use included hospitalizations, outpatient services, and medications. Survival beyond the trial period was estimated using data from the Framingham Heart Study, the Saskatchewan Health database, and the Worcester Heart Attack Registry. The incremental cost-effectiveness of eplerenone in cost per life-year and quality-adjusted life-year gained was estimated. The perspective of the Swiss third party payers was used. Daily treatment costs of eplerenone were set at CHF 3.88. All other resources were valued on the basis of official tariffs. Discounting of the results was performed at a rate of 3%. Results: The number of life-years gained with eplerenone was 0.1083 based on Framingham, 0.0661 with Saskatchewan and 0.1518 with Worcester survival estimates. Total costs were CHF 1,028 higher over the trial period in the eplerenone arm, due to drug cost. The incremental cost-effectiveness ratio was CHF 10,145 per life-year gained with Framingham, CHF 16,178 with Saskatchewan, and CHF 7,693 with Worcester survival estimates. The corresponding costs per QALY were CHF 15,219, CHF 23,965 and CHF 11,337, respectively. Conclusion: Eplerenone is effective in reducing mortality and, in Switzerland, is also cost-effective in increasing years of life for patients with LVSD after AM

Detection of a Cool, Accretion-Shock-Generated X-Ray Plasma in EX Lupi During the 2008 Optical Eruption

EX Lupi is the prototype for a class of young, pre-main-sequence stars which are observed to undergo irregular, presumably accretion-generated, optical outbursts that result in a several magnitude rise of the optical flux. EX Lupi was observed to optically erupt in 2008 January, triggering Chandra ACIS Target of Opportunity observations shortly thereafter. We find very strong evidence that most of the X-ray emission in the first few months after the optical outburst is generated by accretion of circumstellar material onto the stellar photosphere. Specifically, we find a strong correlation between the decreasing optical and X-ray fluxes following the peak of the outburst in the optical, which suggests that these observed declines in both the optical and X-ray fluxes are the result of declining accretion rate. In addition, in our models of the X-ray spectrum, we find strong evidence for an approx 0.4 keV plasma component, as expected for accretion shocks on low-mass, pre-main-sequence stars. From 2008 March through October, this cool plasma component appeared to fade as EX Lupi returned to its quiescent level in the optical, consistent with a decrease in the overall emission measure of accretion-shock-generated plasma. The overall small increase of the X-ray flux during the optical outburst of EX Lupi is similar to what was observed in previous X-ray observations of the 2005 optical outburst of the EX Lupi-type star V1118 Ori but contrasts with the large increase of the X-ray flux from the erupting young star V1647 Ori during its 2003 and 2008 optical outbursts