90 research outputs found
Interdisciplinary European guidelines on surgery of severe obesity
W 2005 roku, dzięki wspólnemu wysiłkowi głównych europejskich
towarzystw naukowych aktywnych na polu leczenia otyłości został
powołany zespół ekspertów nazwany Bariatryczno-Naukową
Grupą Badawczą (BSCG). Towarzystwami, które stworzyły ten
zespół i oddelegowały swoich przedstawicieli do prac w opracowaniu
wytycznych były: Międzynarodowe Towarzystwo Chirurgicznego
Leczenia Otyłości (IFSO), Oddział Europejski Międzynarodowego
Towarzystwa Chirurgicznego Leczenia Otyłości
(IFSO-EC), Europejskie Towarzystwo Badań nad Otyłością
(EASO), Europejska Grupa ds. Otyłości u Dzieci (ECOG) (razem
z Międzynarodową Grupą Zwalczania Otyłości). Bariatryczno-Naukowa
Grupa Badawcza składała się z władz reprezentujących
powyższe towarzystwa (czterech czynnych przewodniczących,
dwóch byłych, jeden honorowy, dwóch dyrektorów wykonawczych),
a także najwybitniejszych ekspertów w tej dziedzinie. Skład BSCG pozwolił na całościowe objęcie zagadnienia leczenia
otyłości olbrzymiej z uwzględnieniem różnorodności geograficznej
i etnicznej Europy. Członkowie BSCG odbyli wiele spotkań
poświęconych stworzeniu wytycznych, które odzwierciedlałyby
współczesną wiedzę i doświadczenie w zakresie leczenia
otyłości olbrzymiej.In 2005, for the first time in European history, an extraordinary expert
panel named BSCG (Bariatric Scientific Collaborative Group),
was appointed through joint effort of the major European scientific
societies which are active in the field of obesity management. Societies
that constituted this panel were: IFSO - International Federation
for the Surgery of Obesity, IFSO-EC - International Federation
for the Surgery of Obesity - European Chapter, EASO - European Association for Study of Obesity, ECOG - European
Childhood Obesity Group, together with the IOTF (International
Obesity Task Force) which was represented during the completion
process by its representative. The BSCG was composed not
only of the top officers representing the respective scientific societies
(four acting presidents, two past presidents, one honorary president,
two executive directors), but was balanced with the presence
of many other key opinion leaders in the field of obesity. The
BSCG composition allowed the coverage of key disciplines in comprehensive
obesity management, as well as reflecting European
geographical and ethnic diversity. This joint BSCG expert panel
convened several meetings which were entirely focused on guidelines
creation, during the past 2 years. There was a specific effort
to develop clinical guidelines, which will reflect current knowledge,
expertise and evidence based data on morbid obesity treatment
BariSurg trial: Sleeve gastrectomy versus Roux-en-Y gastric bypass in obese patients with BMI 35–60 kg/m2 – a multi-centre randomized patient and observer blind non-inferiority trial
Background: Roux-en-Ygastric bypass (RYGB) and sleeve gastrectomy (SG) rank among the most frequently applied bariatric procedures worldwide due to their positive risk/benefit correlation. A systematic review revealed a similar excess weight loss (EWL) 2 years postoperatively between SG and RYGB. However, there is a lack of randomized controlled multi-centre trials comparing SG and RYGB, not only concerning EWL, but also in terms of remission of obesity-related co-morbidities, gastroesophageal reflux disease (GERD) and quality of life (QoL) in the mid- and long-term. Methods: The BariSurg trial was designed as a multi-centre, randomized controlled patient and observer blind trial. The trial protocol was approved by the corresponding ethics committees of the centres. To demonstrate EWL non-inferiority of SG compared to RYGB, power calculation was performed according to a non-inferiority study design. Morbidity, mortality, remission of obesity-related co-morbidities, GERD course and QoL are major secondary endpoints. 248 patients between 18 and 70 years, with a body mass index (BMI) between 35–60 kg/m2 and indication for bariatric surgery according to the most recent German S3-guidelines will be randomized. The primary and secondary endpoints will be assessed prior to surgery and afterwards at discharge and at the time points 3–6, 12, 24, 36, 48 and 60 months postoperatively. Discussion: With its five year follow-up, the BariSurg-trial will provide further evidence based data concerning the impact of SG and RYGB on EWL, remission of obesity-related co-morbidities, the course of GERD and QoL. Trial registration: The trial protocol has been registered in the German Clinical Trials Register DRKS0000476
The History and Prehistory of Natural-Language Semantics
Contemporary natural-language semantics began with the assumption that the meaning of a sentence could be modeled by a single truth condition, or by an entity with a truth-condition. But with the recent explosion of dynamic semantics and pragmatics and of work on non- truth-conditional dimensions of linguistic meaning, we are now in the midst of a shift away from a truth-condition-centric view and toward the idea that a sentence’s meaning must be spelled out in terms of its various roles in conversation. This communicative turn in semantics raises historical questions: Why was truth-conditional semantics dominant in the first place, and why were the phenomena now driving the communicative turn initially ignored or misunderstood by truth-conditional semanticists? I offer a historical answer to both questions. The history of natural-language semantics—springing from the work of Donald Davidson and Richard Montague—began with a methodological toolkit that Frege, Tarski, Carnap, and others had created to better understand artificial languages. For them, the study of linguistic meaning was subservient to other explanatory goals in logic, philosophy, and the foundations of mathematics, and this subservience was reflected in the fact that they idealized away from all aspects of meaning that get in the way of a one-to-one correspondence between sentences and truth-conditions. The truth-conditional beginnings of natural- language semantics are best explained by the fact that, upon turning their attention to the empirical study of natural language, Davidson and Montague adopted the methodological toolkit assembled by Frege, Tarski, and Carnap and, along with it, their idealization away from non-truth-conditional semantic phenomena. But this pivot in explana- tory priorities toward natural language itself rendered the adoption of the truth-conditional idealization inappropriate. Lifting the truth-conditional idealization has forced semanticists to upend the conception of linguistic meaning that was originally embodied in their methodology
Comment on: Can genetics help predict efficacy of bariatric surgery? An analysis of microribonucleic acid profiles
Are There Gender-Specific Aspects in Obesity and Metabolic Surgery? Data Analysis from the German Bariatric Surgery Registry
Koinzidenz von anti-Centromer- und anti-Scl-70-Antikörpern bei Patienten mit systemischer Sklerose
Proximal (classic) gastric bypass
The intention of this procedure is a restriction of the size of the stomach by cutting it proximally and the creation of malabsorption by dividing the small intestine into an alimentary (Roux limb) and a biliopancreatic segment (Fig. 3.1). Both goals (restriction and malabsorption) are reached in one operation; it is therefore referred to as “combined procedure.”SCOPUS: ch.binfo:eu-repo/semantics/publishe
Antibody-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes
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