A new diagrammatic representation for correlation functions in the in-in formalism

In this paper we provide an alternative method to compute correlation functions in the in-in formalism, with a modified set of Feynman rules to compute loop corrections. The diagrammatic expansion is based on an iterative solution of the equation of motion for the quantum operators with only retarded propagators, which makes each diagram intrinsically local (whereas in the standard case locality is the result of several cancellations) and endowed with a straightforward physical interpretation. While the final result is strictly equivalent, as a bonus the formulation presented here also contains less graphs than other diagrammatic approaches to in-in correlation functions. Our method is particularly suitable for applications to cosmology.Comment: 14 pages, matches the published version. includes a modified version of axodraw.sty that works with the Revtex4 clas

Systems approaches and algorithms for discovery of combinatorial therapies

Effective therapy of complex diseases requires control of highly non-linear complex networks that remain incompletely characterized. In particular, drug intervention can be seen as control of signaling in cellular networks. Identification of control parameters presents an extreme challenge due to the combinatorial explosion of control possibilities in combination therapy and to the incomplete knowledge of the systems biology of cells. In this review paper we describe the main current and proposed approaches to the design of combinatorial therapies, including the empirical methods used now by clinicians and alternative approaches suggested recently by several authors. New approaches for designing combinations arising from systems biology are described. We discuss in special detail the design of algorithms that identify optimal control parameters in cellular networks based on a quantitative characterization of control landscapes, maximizing utilization of incomplete knowledge of the state and structure of intracellular networks. The use of new technology for high-throughput measurements is key to these new approaches to combination therapy and essential for the characterization of control landscapes and implementation of the algorithms. Combinatorial optimization in medical therapy is also compared with the combinatorial optimization of engineering and materials science and similarities and differences are delineated.Comment: 25 page

Spinor Helicity and Dual Conformal Symmetry in Ten Dimensions

The spinor helicity formalism in four dimensions has become a very useful tool both for understanding the structure of amplitudes and also for practical numerical computation of amplitudes. Recently, there has been some discussion of an extension of this formalism to higher dimensions. We describe a particular implementation of the spinor-helicity method in ten dimensions. Using this tool, we study the tree-level S-matrix of ten dimensional super Yang-Mills theory, and prove that the theory enjoys a dual conformal symmetry. Implications for four-dimensional computations are discussed.Comment: 24 pages, 1 figure

Vanishing Cosmological Constant by Gravitino-Dressed Compactification of 11D Supergravity

We consider compactifications induced by the gravitino field of eleven dimensional supergravity. Such compactifications are not trivial in the sense that the gravitino profiles are not related to pure bosonic ones by means of a supersymmetry transformation. The basic property of such backgrounds is that they admit $\psi$-torsion although they have vanishing Riemann tensor. Thus, these backgrounds may be considered also as solutions of the teleparallel formulation of supergravity. We construct two classes of solutions, one with both antisymmetric three-form field, gravity and gravitino and one with only gravity and gravitino. In these classes of solutions, the internal space is a parallelized compact manifold, so that it does not inherit any cosmological constant to the external spacetime. The latter turns out to be flat Minkowski in the maximally symmetric case. The elimination of the cosmological constant in the spontaneously compactified supergravity seems to be a generic property based on the trading of the cosmological constant for parallelizing torsion.Comment: 17 pages, no figure

The Dropping of In-Medium Hadron Mass in Holographic QCD

We study the baryon density dependence of the vector meson spectrum using the D4/D6 system together with the compact D4 baryon vertex. We find that the vector meson mass decreases almost linearly in density at low density for small quark mass, but saturates to a finite non-zero value for large density. We also compute the density dependence of the $\eta\prime$ mass and the $\eta\prime$ velocity. We find that in medium, our model is consistent with the GMOR relation up to a few times the normal nuclear density. We compare our hQCD predictions with predictions made based on hidden local gauge theory that is constructed to model QCD.Comment: 20 pages, 7 figure

Form Factors in N=4 Super Yang-Mills and Periodic Wilson Loops

We calculate form factors of half-BPS operators in N=4 super Yang-Mills theory at tree level and one loop using novel applications of recursion relations and unitarity. In particular, we determine the expression of the one-loop form factors with two scalars and an arbitrary number of positive-helicity gluons. These quantities resemble closely the MHV scattering amplitudes, including holomorphicity of the tree-level form factor, and the expansion in terms of two-mass easy box functions of the one-loop result. Next, we compare our result for these form factors to the calculation of a particular periodic Wilson loop at one loop, finding agreement. This suggests a novel duality relating form factors to periodic Wilson loops.Comment: 26 pages, 10 figures. v2: typos fixed, comments adde

WIMP-nucleus scattering in chiral effective theory

We discuss long-distance QCD corrections to the WIMP-nucleon(s) interactions in the framework of chiral effective theory. For scalar-mediated WIMP-quark interactions, we calculate all the next-to-leading-order corrections to the WIMP-nucleus elastic cross-section, including two-nucleon amplitudes and recoil-energy dependent shifts to the single-nucleon scalar form factors. As a consequence, the scalar-mediated WIMP-nucleus cross-section cannot be parameterized in terms of just two quantities, namely the neutron and proton scalar form factors at zero momentum transfer, but additional parameters appear, depending on the short-distance WIMP-quark interaction. Moreover, multiplicative factorization of the cross-section into particle, nuclear and astro-particle parts is violated. In practice, while the new effects are of the natural size expected by chiral power counting, they become very important in those regions of parameter space where the leading order WIMP-nucleus amplitude is suppressed, including the so-called "isospin-violating dark matter" regime. In these regions of parameter space we find order-of-magnitude corrections to the total scattering rates and qualitative changes to the shape of recoil spectra.Comment: 23 pages, 6 figures, 1 tabl

Fermion Masses in Emergent Electroweak Symmetry Breaking

We consider the generation of fermion masses in an emergent model of electroweak symmetry breaking with composite $W,Z$ gauge bosons. A universal bulk fermion profile in a warped extra dimension is used for all fermion flavors. Electroweak symmetry is broken at the UV (or Planck) scale where boundary mass terms are added to generate the fermion flavor structure. This leads to flavor-dependent nonuniversality in the gauge couplings. The effects are suppressed for the light fermion generations but are enhanced for the top quark where the $Zt{\bar t}$ and $Wt{\bar b}$ couplings can deviate at the $10-20$ level in the minimal setup. By the AdS/CFT correspondence our model implies that electroweak symmetry is not a fundamental gauge symmetry. Instead the Standard Model with massive fermions and $W,Z$ gauge bosons is an effective chiral Lagrangian for some underlying confining strong dynamics at the TeV scale, where mass is generated without a Higgs mechanism.Comment: modified discussion in Sec 3.1, version published in JHE

Radiation effects in glasses used for immobilization of high-level waste and plutonium disposition

This paper is a comprehensive review of the state-of-knowledge in the field of radiation effects in glasses that are to be used for the immobilization of high-level nuclear waste and plutonium disposition. The current status and issues in the area of radiation damage processes, defect generation, microstructure development, theoretical methods and experimental methods ase reviewed. Questions of fundamental and technological interest that offer opportunities for research are identified