20 research outputs found
Determinants of Credit Risk: Empirical Evidence from Asia-Pacific Banking Industry
This thesis carries out an empirical analysis of the determinants of credit risk based on Asia-Pacific banks. It has been debated for a number of years that the banks in that region are healthier than those in the US and the Europe. Presently, there are many papers available on the topic of credit risk determinants, but only a limited number of them focus on Asia-Pacific banks. Furthermore, these papers are generally based on some particular Asia-Pacific countries and none of these papers successfully identify the impact of the recent financial crisis to the whole region. Motivated by this, the author conducts a brief introduction and presents some background information on the Asia-Pacific history and the banking industry, followed by a review of the recent literature. While discovering gaps between previous studies, the author proposes three stages of the research, and carries out an empirical analysis. The first stage of the research contains only bank-level and macroeconomic variables. The author finds that loan quality, management efficiency, and bank size are significant at the bank level, and country‟s unemployment rate and inflation rate are significant at the macroeconomic level. To examine the contrasting views on the impact of financial crisis in Asia-Pacific banking industry, this thesis gives a further analysis and concludes that the recent economic downturn has no significant impact to banks in that region. The author also takes an additional research with a group of country dummy variables, and it turns out that only Philippines and Pakistan are subjective to the non-performing loans. Based on this result, the author concludes that banks in these two countries are more exposed to credit risk than any other Asia-Pacific countries
Use of Traditional Chinese Medicine and Its Impact on Medical Cost among Urban Ischemic Stroke Inpatients in China: A National Cross-Sectional Study
Background. Traditional Chinese medicine (TCM) has long been widely adopted by the Chinese people and has been covered by China’s basic medical insurance schemes to treat ischemic stroke. Previous research has mainly highlighted the therapy effect of TCM on ischemic stroke patients. Some studies have demonstrated that employing TCM can reduce the medical burden on other diseases. But no research has explored whether using TCM could reduce inpatient medical cost for ischemic stroke in mainland China. The purpose of this study is to investigate the impact of the use of TCM on the total inpatient cost of ischemic stroke and to explore whether TCM has played the role of being complementary to, or an alternative for, conventional medicine to treat ischemic stroke. Methods. We conducted a national cross-sectional analysis based on a 5% random sample from claims data of China Urban Employee Basic Medical Insurance (UEBMI) and Urban Resident Basic Medical Insurance (URBMI) schemes in 2015. Mann–Whitney test was used to compare unadjusted total inpatient cost, conventional medication cost, and nonpharmacy cost estimates. Ordinary least square regression analysis was performed to compare demographics-adjusted total inpatient cost and to examine the association between TCM cost and conventional medication cost. Results. A total of 47321 urban inpatients diagnosed with ischemic stroke were identified in our study, with 92.6% (43843) of the patients using TCM in their inpatient treatment. Total inpatient cost for TCM users was significantly higher than TCM nonusers (USD 1217 versus USD 1036, P<0.001). Conventional medication cost was significantly lower for TCM users (USD 335 versus USD 436, P<0.001). The average cost of TCM per patient among TCM users was USD 289. Among TCM users, conventional medication costs were found to be positively associated with TCM cost after adjusting for confounding factors (Coef. = 0.144, P<0.001). Conclusion. Although the use of TCM reduced the cost of conventional medicine compared with TCM nonusers, TCM imposed an extra financial component on the total inpatient cost on TCM users. Our study suggests that TCM mainly played a complementary role to conventional medicine in ischemic stroke treatment in mainland China
Medical insurance payment schemes and patient medical expenses: a cross-sectional study of lung cancer patients in urban China
BackgroundAs the main cause of cancer death, lung cancer imposes seriously health and economic burdens on individuals, families, and the health system. In China, there is no national study analyzing the hospitalization expenditures of different payment methods by lung cancer inpatients. Based on the 2010-2016 database of insured urban resident lung cancer inpatients from the China Medical Insurance Research Association (CHIRA), this paper aims to investigate the characteristics and cost of hospitalized lung cancer patient, to examine the differences in hospital expenses and patient out-of-pocket (OOP) expenses under four medical insurance payment methods: fee-for-service (FFS), per-diem payments, capitation payments (CAP) and case-based payments, and to explore the medical insurance payment method that can be conducive to controlling the cost of lung cancer.MethodThis is a 2010-2016, 7-year cross-sectional study. CHIRA data are not available to researchers after 2016. The Medical Insurance Database of CHIRA was screened using the international disease classification system to yield 28,200 inpatients diagnosed with lung cancer (ICD-10: C34, C34.0, C34.1, C34.2, C34.3, C34.8, C34.9). The study includes descriptive analysis and regression analysis based on generalized linear models (GLM).ResultsThe average patient age was 63.4 years and the average length of hospital stay (ALOS) was 14.2 day; 60.7% of patients were from tertiary hospitals; and 45% were insured by FFS. The per-diem payment had the lowest hospital expenses (RMB7496.00/US208.52). Compared with FFS hospital expenses, per-diem was 21.3% lower (95% CI = -0.265, -0.215) and case-based payment was 8.4% lower (95% CI = -0.151, -0.024). Compared with the FFS, OOP expenses, per-diem payments were 9.2% lower (95% CI = -0.130, -0.063) and CAP was 15.1% lower (95% CI = -0.151, -0.024).ConclusionFor lung cancer patients, per-diem payment generated the lowest hospital expenses, while CAP meant patients bore the lowest OOP costs. Policy makers are suggested to give priority to case-based payments to achieve a tripartite balance among medical insurers, hospitals, and insured members. We also recommend future studies comparing the disparities of various diseases for the cause of different medical insurance schemes
Qingchang Wenzhong Decoction Attenuates DSS-Induced Colitis in Rats by Reducing Inflammation and Improving Intestinal Barrier Function via Upregulating the MSP/RON Signalling Pathway
Ulcerative colitis (UC) is a chronic, nonspecific, inflammatory disease for which an effective treatment is lacking. Our previous study found that Qingchang Wenzhong Decoction (QCWZD) can significantly improve the clinical symptoms of UC and ameliorate dextran sulphate sodium- (DSS-) induced ulcerative colitis in rats by downregulating the IP10/CXCR3 axis–mediated inflammatory response. The purpose of the present study was to further explore the mechanism of QCWZD for UC in rats models, which were established by 7-day administration of 4.5% dextran sulphate sodium solution. QCWZD was administered daily for 7 days; then we determined the serum macrophage-stimulating protein concentration (MSP) and recepteur d’origine nantais (RON) expression and its downstream proteins (protein kinase B [Akt], phosphorylated [p] Akt, occludin, zona occluden- [ZO-] 1, and claudin-2) in colon tissue using Western blotting and quantitative polymerase chain reaction. In DSS-induced UC, QCWZD significantly alleviated colitis-associated inflammation, upregulated serum MSP expression and RON expression in the colon, reduced the pAkt levels, promoted colonic occluding and ZO-1 expression, and depressed claudin-2 expression. In conclusion, the MSP/RON signalling pathway plays an important role in the pathogenesis of UC by involving the inflammatory response and improving intestinal barrier function. QCWZD appears to attenuate DSS-induced UC in rats by upregulating the MSP/RON signalling pathway
Determinants of Credit Risk: Empirical Evidence from Asia-Pacific Banking Industry
This thesis carries out an empirical analysis of the determinants of credit risk based on Asia-Pacific banks. It has been debated for a number of years that the banks in that region are healthier than those in the US and the Europe. Presently, there are many papers available on the topic of credit risk determinants, but only a limited number of them focus on Asia-Pacific banks. Furthermore, these papers are generally based on some particular Asia-Pacific countries and none of these papers successfully identify the impact of the recent financial crisis to the whole region. Motivated by this, the author conducts a brief introduction and presents some background information on the Asia-Pacific history and the banking industry, followed by a review of the recent literature. While discovering gaps between previous studies, the author proposes three stages of the research, and carries out an empirical analysis. The first stage of the research contains only bank-level and macroeconomic variables. The author finds that loan quality, management efficiency, and bank size are significant at the bank level, and country‟s unemployment rate and inflation rate are significant at the macroeconomic level. To examine the contrasting views on the impact of financial crisis in Asia-Pacific banking industry, this thesis gives a further analysis and concludes that the recent economic downturn has no significant impact to banks in that region. The author also takes an additional research with a group of country dummy variables, and it turns out that only Philippines and Pakistan are subjective to the non-performing loans. Based on this result, the author concludes that banks in these two countries are more exposed to credit risk than any other Asia-Pacific countries
A Data Fusion Method for Generating Hourly Seamless Land Surface Temperature from Himawari-8 AHI Data
High temporal resolution and spatially complete (seamless) land surface temperature (LST) play a crucial role in numerous geoscientific aspects. This paper proposes a data fusion method for producing hourly seamless LST from Himawari-8 Advanced Himawari Imager (AHI) data. First, the high-quality hourly clear-sky LST was retrieved from AHI data by an improved temperature and emissivity separation algorithm; then, the hourly spatially complete China Land Data Assimilation System (CLDAS) LST was calibrated by a bias correction method. Finally, the strengths of the retrieved AHI LST and bias-corrected CLDAS LST were combined by the multiresolution Kalman filter (MKF) algorithm to generate hourly seamless LST at different spatial scales. Validation results showed the bias and root mean square error (RMSE) of the fused LST at a finer scale (0.02°) were −0.65 K and 3.38 K under cloudy sky conditions, the values were −0.55 K and 3.03 K for all sky conditions, respectively. The bias and RMSE of the fused LST at the coarse scale (0.06°) are −0.46 K and 3.11 K, respectively. This accuracy is comparable to the accuracy of all-weather LST derived by various methods reported in the published literature. In addition, we obtained the consistent LST images across different scales. The seamless finer LST data over East Asia can not only reflect the spatial distribution characteristics of LST during different seasons, but also exactly present the diurnal variation of the LST. With the proposed method, we have produced a 0.02° seamless LST dataset from 2016 through 2021 that is freely available at the National Tibetan Plateau Data Center. It is the first time that we can obtain the hourly seamless LST data from AHI
A Data Fusion Method for Generating Hourly Seamless Land Surface Temperature from Himawari-8 AHI Data
High temporal resolution and spatially complete (seamless) land surface temperature (LST) play a crucial role in numerous geoscientific aspects. This paper proposes a data fusion method for producing hourly seamless LST from Himawari-8 Advanced Himawari Imager (AHI) data. First, the high-quality hourly clear-sky LST was retrieved from AHI data by an improved temperature and emissivity separation algorithm; then, the hourly spatially complete China Land Data Assimilation System (CLDAS) LST was calibrated by a bias correction method. Finally, the strengths of the retrieved AHI LST and bias-corrected CLDAS LST were combined by the multiresolution Kalman filter (MKF) algorithm to generate hourly seamless LST at different spatial scales. Validation results showed the bias and root mean square error (RMSE) of the fused LST at a finer scale (0.02°) were −0.65 K and 3.38 K under cloudy sky conditions, the values were −0.55 K and 3.03 K for all sky conditions, respectively. The bias and RMSE of the fused LST at the coarse scale (0.06°) are −0.46 K and 3.11 K, respectively. This accuracy is comparable to the accuracy of all-weather LST derived by various methods reported in the published literature. In addition, we obtained the consistent LST images across different scales. The seamless finer LST data over East Asia can not only reflect the spatial distribution characteristics of LST during different seasons, but also exactly present the diurnal variation of the LST. With the proposed method, we have produced a 0.02° seamless LST dataset from 2016 through 2021 that is freely available at the National Tibetan Plateau Data Center. It is the first time that we can obtain the hourly seamless LST data from AHI
Simultaneous retrieval of land surface temperature and emissivity from the FengYun-4A advanced geosynchronous radiation imager
This paper extends a new temperature and emissivity separation (TES) algorithm for retrieving land surface temperature and emissivity (LST and LSE) to the Advanced Geosynchronous Radiation Imager (AGRI) onboard Fengyun-4A, China’s newest geostationary meteorological satellite. The extended TES algorithm was named the AGRI TES algorithm. The AGRI TES algorithm employs a modified water vapor scaling (WVS) method and a recalibrated empirical function over vegetated surfaces. In situ validation and cross-validation are utilized to investigate the accuracy of the retrieved LST and LSE. LST validation using the collected field measurements showed that the mean bias and RMSE of AGRI TES LST are 0.58 and 2.93 K in the daytime and −0.30 K and 2.18 K at nighttime, respectively; the AGRI official LST is systematically underestimated. Compared with the MODIS LST and LSE products (MYD21), the average bias and RMSE of AGRI TES LST are −0.26 K and 1.65 K, respectively. The AGRI TES LSE outperforms the AGRI official LSE in terms of accuracy and spatial integrity. This study demonstrates the good performance of the AGRI TES algorithm for the retrieval of high-quality LST and LSE, and the potential of the AGRI TES algorithm in producing operational LST and LSE products
Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors
Pyrrolizidine alkaloids (PAs) present distinct toxicity potencies depending on their metabolites and in vivo toxicokinetics. To represent the potency differences of various PAs, the interim relative potency (REP) factors have been derived. However, little is known about the risk assessment for (herbal) teas when taking REP factors into account. In this study, a set of 68 individual 1,2-unsaturated PA in 21 types of (herbal) teas was analyzed using LC-MS/MS. The REP factors for these PAs were applied on the PA levels. The margin of exposure (MOE) approach was employed to assess the risks of the exposure to PAs due to consumption of (herbal) teas. The results show that the total PA levels ranged from 13.4 to 286,682.2 μg/kg d.m., which were decreased by REP correction in most of the teas. The MOE values for tephroseris, borage and lemon balm (melissa) tea based on REP-corrected PA levels were below 10,000, assuming daily consumption of one cup of tea during a lifetime, indicating that consuming these teas may raise a concern. Our study also indicates a priority for risk management for tephroseris tea, as having nephrosis tea for more than 11.2 weeks during a 75-year lifetime would result in an MOE of 10,000