4,894 research outputs found
A novel approach to design low-cost two-stage frequency-response masking filters
The multistage frequency-response masking (FRM) technique is widely used to reduce the complexity of a filter when the transition bandwidth is extremely small. In this brief, a real generalized two-stage FRM filter without any constraint on the subfilters or the interpolation factors was proposed. New principles and equations were deduced to determine the design parameters. The subfilters were then jointly optimized using non-linear optimization. Experiential results show that when the proposed algorithm obtains different solutions with the conventional algorithm, the solution of the proposed approach is better with less number of filter coefficients and sometimes with lower delay as well than the conventional two-stage FRM, which can lead to a reduced hardware cost in applications
Poly[bis[chloridocopper(I)]-μ4-1,4-bis[1-(3-pyridylmethyl)-1H-benzimidazol-2-yl]butane]
The title CuI coordination polymer, [Cu2Cl2(C30H28N6)]n, was obtained by reaction of CuCl2·2H2O and 1,4-bis[1-(3-pyridylmethyl)-1H-benzimidazol-2-yl]butane. Each CuI cation is three-coordinated by a ClN2 donor set. The anion acts as a tetradentate ligand, linking CuI centres into a polymeric chain
A reconfigurable sound wave decomposition filterbank for hearing aids based on nonlinear transformation
Hearing impaired people have their own hearing loss characteristics and listening preferences. Therefore hearing aid system should become more natural, humanized and personalized, which requires the filterbank in hearing aids provides flexible sound wave decomposition schemes, so that patients are likely to use the most suitable scheme for their own hearing compensation strategy. In this paper, a reconfigurable sound wave decomposition filterbank is proposed. The prototype filter is first cosine modulated to generate uniform subbands. Then by non-linear transformation the uniform subbands are mapped to nonuniform subbands. By changing the control parameters, the nonlinear transformation changes which leads to different subbands allocations. It provides four different sound wave decomposition schemes without changing the structure of the filterbank. The performance of the proposed reconfigurable filterbank was compared with that of fixed filerbanks, fully customizable filterbanks and other existing reconfigurable filterbanks. It is shown that the proposed filterbank provides satisfactory matching performance as well as low complexity and delay, which make it suitable for real hearing aid applications
Fractional Denoising for 3D Molecular Pre-training
Coordinate denoising is a promising 3D molecular pre-training method, which
has achieved remarkable performance in various downstream drug discovery tasks.
Theoretically, the objective is equivalent to learning the force field, which
is revealed helpful for downstream tasks. Nevertheless, there are two
challenges for coordinate denoising to learn an effective force field, i.e. low
coverage samples and isotropic force field. The underlying reason is that
molecular distributions assumed by existing denoising methods fail to capture
the anisotropic characteristic of molecules. To tackle these challenges, we
propose a novel hybrid noise strategy, including noises on both dihedral angel
and coordinate. However, denoising such hybrid noise in a traditional way is no
more equivalent to learning the force field. Through theoretical deductions, we
find that the problem is caused by the dependency of the input conformation for
covariance. To this end, we propose to decouple the two types of noise and
design a novel fractional denoising method (Frad), which only denoises the
latter coordinate part. In this way, Frad enjoys both the merits of sampling
more low-energy structures and the force field equivalence. Extensive
experiments show the effectiveness of Frad in molecular representation, with a
new state-of-the-art on 9 out of 12 tasks of QM9 and on 7 out of 8 targets of
MD17
(E)-N′-(4-Methoxybenzylidene)-3-nitrobenzohydrazide
In the title compound, C15H13N3O4, the two substituted benzene rings form a dihedral angle of 5.0 (3)°. In the crystal, intermolecular N—H⋯O hydrogen bonds link molecules into chains along the b axis
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