Young people's participation in the development of a self-care intervention--a multi-site formative research study.

The poor outcomes of young people with chronic health conditions indicate that current services and self-care programmes are not meeting the needs of young people. How young people self-manage their condition impacts on long-term health outcomes, but there is little published evidence that details the development of self-care programmes and their most effective components. This article reports on an innovative formative research study, the purpose of which was to develop a self-care intervention prototype. Participants were 87 young people, aged 12-17, and seven young adult facilitators, aged 18-25, with type 1 diabetes or asthma. Each contributed to talking groups exploring themes that young people wanted to be addressed within a self-care programme. Instead of being focused on 'illness', young people's main concerns were directed toward 'life as an adolescent', while at the same time building sustainable daily routines of self-care. Overall, this article illustrates the process of initiating and implementing a developmental approach focused on young people, while also demonstrating the tailored self-care intervention that the process developed. This approach can be used to involve young people in the design and development of other conditions that rely on self-care interventions

Epidemiological Interactions between Urogenital and Intestinal Human Schistosomiasis in the Context of Praziquantel Treatment across Three West African Countries

© 2015 Knowles et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The attached file is the published version of the article

First-principles calculation of the intersublattice exchange interactions and Curie temperatures of full Heusler alloys Ni2MnX (X=Ga, In, Sn, Sb)

The interatomic exchange interactions and Curie temperatures in Ni-based full Heusler alloys Ni2MnX with X=Ga, In, Sn and Sb are studied within the framework of the density-functional theory. The calculation of the exchange parameters is based on the frozen-magnon approach. Despite closeness of the experimental Curie temperatures for all four systems their magnetism appeared to differ strongly. This difference involves both the Mn-Mn and Mn-Ni exchange interactions. The Curie temperatures, Tc, are calculated within the mean-field approximation by solving a matrix equation for a multi-sublattice system. Good agreement with experiment for all four systems is obtained. The role of different exchange interactions in the formation of Tc of the systems is discussed.Comment: 6 pages, 4 figure

Unravelling Active Galactic Nuclei

A complete flat-spectrum radio-loud sample of AGN includes a significant fraction of Seyfert-like AGN including a NLS1. Analysis of their optical spectra suggests that the reddest continuum colours are either associated with AGN in nearby resolved galaxies, or distant quasars showing relatively narrow permitted emission lines.Comment: Poster contribution presented at the Joint MPE,AIP,ESO workshop on NLS1s, Bad Honnef, Dec. 1999, to appear in New Astronomy Reviews; also available at http://wave.xray.mpe.mpg.de/conferences/nls1-worksho

Non-functional immunoglobulin G transcripts in a case of hyper-immunoglobulin M syndrome similar to type 4

86% of immunoglobulin G (IgG) heavy-chain gene transcripts were found to be non-functional in the peripheral blood B cells of a patient initially diagnosed with common variable immunodeficiency, who later developed raised IgM, whereas no non-functionally rearranged transcripts were found in the cells of seven healthy control subjects. All the patient's IgM heavy-chain and κ light-chain transcripts were functional, suggesting that either non-functional rearrangements were being selectively class-switched to IgG, or that receptor editing was rendering genes non-functional after class-switching. The functional γ-chain sequences showed a normal rate of somatic hypermutation while non-functional sequences contained few somatic mutations, suggesting that most came from cells that had no functional gene and therefore were not receiving signals for hypermutation. However, apoptosis of peripheral blood lymphocytes was not impaired. No defects have been found in any of the genes currently known to be responsible for hyper-IgM syndrome but the phenotype fits best to type 4

Black Hole Mass Estimates of Radio Selected Quasars

The black hole (BH) mass in the centre of AGN has been estimated for a sample of radio-selected flat-spectrum quasars to investigate the relationship between BH mass and radio properties of quasars. We have used the virial assumption with measurements of the H$\beta$ FWHM and luminosity to estimate the central BH mass. In contrast to previous studies we find no correlation between BH mass and radio power in these AGN. We find a range in BH mass similar to that seen in radio-quiet quasars from previous studies. We believe the reason that the low BH mass radio-loud quasars have not been measured in previous studies is due to optical selection effects which tend to miss the less optically luminous radio-loud sources.Comment: 22 pages, 7 figures, accepted for publication in Ap

Space Telescope Imaging Spectrograph slitless observations of Small Magellanic Cloud Planetary Nebulae: a study on morphology, emission line intensity, and evolution

A sample of 27 Planetary Nebulae (PNs) in the Small Magellanic Clouds (SMC) have been observed with the Hubble Space Telescope Imaging Spectrograph (HST/STIS) to determine their morphology, size, and the spatial variation of the ratios of bright emission lines. The morphologies of SMC PNs are similar to those of LMC and Galactic PNs. However, only a third of the resolved SMC PNs are asymmetric, compared to half in the LMC. The low metallicity environment of the SMC seems to discourage the onset of bipolarity in PNs. We measured the line intensity, average surface brightness (SB), and photometric radius of each nebula in halpha, hbeta, [O III] lambda4959 and 5007, [NII] 6548 and 6584, [S II] lambda6716 and 5731, He I 6678, and [OI] 6300 and 6363. We show that the surface brightness to radius relationship is the same as in LMC PNs, indicating its possible use as a distance scale indicator for Galactic PNs. We determine the electron densities and the ionized masses of the nebulae where the [S II] lines were measured accurately, and we find that the SMC PNs are denser than the LMC PNs by a factor of 1.5. The average ionized mass of the SMC PNs is 0.3 Msun. We also found that the median [O III]/hbeta intensity ratio in the SMC is about half than the corresponding LMC median. We use Cloudy to model the dependence of the [O III]/hbeta ratio on the oxygen abundance. Our models encompass very well the average observed physical quantities. We suggest that the SMC PNs are principally cooled by the carbon lines, making it hard to study their excitation based on the optical lines at our disposal.Comment: Accepted for publication in the Astrophysical Journal, 30 pages, 13 figures, 6 tables. For high resolution version of Figs 1 to 6, see http://archive.stsci.edu/hst/mcpn/home.htm