Regional Supply Chains: Strengthening Urban-Rural Connections Around the Benefits from Natural Areas

Report of the 2017 Berkley Workshop Held at the Inn at Shelburne Farms, Shelburne, VT - June 201

Who’s Who in the Zoo: Defining Roles and Responsibilities of a Collaborative Health Care Team Abstract

In 2017, 10,748 patients in the acute care setting experienced a sentinel event (The Joint Commission, 2017). As reported by the Joint Commission, 70% of these events could be avoided with a clear understanding and proper communication of the roles and responsibilities of each member of the healthcare team. With clearly defined roles and responsibilities of each team member, nurses can better utilize each member to increase the quality of patient-centered care delivery. To facilitate rich interprofessional communication among students of various health care disciplines (nursing, social work, nutrition, pre-OT/PT, and child life), an Interprofessional Case Study Event was conducted. Participants worked through three phases of care from a case study scenario in which fostering effective communication among the students was vital. We hypothesize that participation in an Interprofessional Case Study Event at the undergraduate level will increase students’ knowledge of the roles and responsibilities of the various health care team members.  Design: A quantitative one-group, pre/post test case study event was conducted with various undergraduate health care students enrolled at Tennessee Technological University. Data were collected using the SPICE-R2 self-report questionnaire.  Results: Our analysis supports a statistically significant difference in students’ perceptions of the roles and responsibilities for collaborative practice pre/post Interprofessional Case Study Event. Conclusion: The implications of this study suggests that providing collaborative learning opportunities for students of health disciplines will increase the understanding of roles and responsibilities of each health professional, resulting in more effective interdisciplinary communication that will lead to improved patient care

The Grizzly, December 2, 2021

How Should We Eat Together? • December Editor\u27s Letter • Mail Center Mishap • Dancing in the Lenfest Once More • Meet Will McCoy • Opinions: Holiday Season on Campus; Growing Concern Over Course Registration • UC Men\u27s Rugby is Back • Field Hockey\u27s Huge Successhttps://digitalcommons.ursinus.edu/grizzlynews/1975/thumbnail.jp

Escaping High Viral Load Exhaustion: CD8 Cells with Altered Tetramer Binding in Chronic Hepatitis B Virus Infection

Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in the face of a high quantity of viral antigen. Although they do not appear to exert immunological pressure in vivo, these CD8 cells are not classically “tolerant” since they proliferate, lyse, and produce antiviral cytokines in vitro. They are characterized by altered HLA/peptide tetramer reactivity, which is not explained by TCR down-regulation or reduced functional avidity and which can be reversed with repetitive stimulation. CD8 cells with altered tetramer binding appear to have a specificity restricted to envelope antigen and not to other HBV antigens, suggesting that mechanisms of CD8 cell dysfunction are differentially regulated according to the antigenic form and presentation of individual viral antigens

City of Cuero Site Analysis and Redevelopment Recommendations

Cuero is a small south Texas town which prides itself on preserving the history and heritage of its community while providing southern hospitality to its residents and visitors.Cuero Development Corporation Master Plan- Developed a plan for the best use of a 4.519-acre property. Conducted a comprehensive assessment of options for the development of the property.Texas Target Communitie

Leaving no one behind? Addressing inequitable HIV outcomes by attending to diversity: A qualitative study exploring the needs of LGBTQI+ young people living with HIV in Zimbabwe

Leaving nobody behind in the fight to end the HIV epidemic as a public health threat depends on addressing inequities in optimal HIV outcomes. Consistently overlooked in research, policy and programming are young lesbian, gay, bisexual, transgender, queer/questioning and intersex (LGBTQI+) people who are living with HIV. This study engaged young LGBTQI+ people in Zimbabwe to better understand their experiences of living with HIV and the support they need. Between September 2022 and February 2023, we conducted qualitative research with 14 LGBTQI+ young people (18–24 years), (two focus group discussions and in-depth interviews with 5/14). All 14 participants were accessing a LGBTQI+ HIV support group at Zvandiri (‘As I Am’), a well-established community-based HIV program. We conducted thematic analysis and key findings informed the collaborative development of internal activities to further enhance inclusivity of LGBTQI+ young people within Zvandiri’s programs. There was consensus among participants that being LGBTQI+ and living with HIV leads to “double stigma and double trouble”, involving physical and verbal harassment, social exclusion and family rejection. Participants concealed their LGBTQI+ identity and HIV status in most situations, and many withheld their HIV status in LGBTQI+ social spaces, including community-led LGBTQI+ services. This negatively impacted their psychosocial well-being and social connectedness. Participants described positive experiences of Zvandiri. Interacting with others living with HIV in a destigmatising environment promoted self-acceptance. However, reflecting their prevailing experiences, participants were cautious about revealing their sexuality and/or gender identity at Zvandiri outside of their support group. Ensuring equitable access to HIV care, including mental health support, relies on understanding the challenges experienced by those most marginalised. Critically important is understanding the impact of intersectional stigma on LGBTQI+ young peoples’ social lives, and their access to services. Community-based HIV support programs are well-positioned to support and advance this group’s health rights

Cross Sectional Survey of Antenatal Educators' Views About Current Antenatal Education Provision

Antenatal education (ANE) is part of National Health Service (NHS) care and is recommended by The National Institute for Health and Care Excellence (NICE) to increase birth preparedness and help pregnant women/birthing people develop coping strategies for labour and birth. We aimed to understand antenatal educator views about how current ANE supports preparedness for childbirth, including coping strategy development with the aim of identifying targets for improvement. A United Kingdom wide, cross-sectional online survey was conducted between October 2019 and May 2020. Antenatal educators including NHS midwives and private providers were purposively sampled. Counts and percentages were calculated for closed responses and thematic analysis used for open text responses. Ninety-nine participants responded, 62% of these did not believe that ANE prepared women for labour and birth. They identified practical barriers to accessing ANE, particularly for marginalised groups, including financial and language barriers. Educators believe class content is medically focused, and teaching is of variable quality with some midwives being ill-prepared to deliver antenatal education. 55% of antenatal educators believe the opportunity to develop coping strategies varies between location and educators and only those women who can pay for non-NHS classes are able to access all the coping strategies that can support them with labour and birth. Antenatal educators believe current NHS ANE does not adequately prepare women for labour and birth, leading to disparities in birth preparedness for those who cannot access non-NHS classes. To reduce this healthcare inequality, NHS classes need to be standardised, with training for midwives in delivering ANE enhanced. [Abstract copyright: © 2024. The Author(s).

Moult cycle specific differential gene expression profiling of the crab Portunus pelagicus

Background: Crustacean moulting is a complex process involving many regulatory pathways. A holistic approach to examine differential gene expression profiles of transcripts relevant to the moulting process, across all moult cycle stages, was used in this study. Custom cDNA microarrays were constructed for Portunus pelagicus. The printed arrays contained 5000 transcripts derived from both the whole organism, and from individual organs such as the brain, eyestalk, mandibular organ and Y-organ from all moult cycle stages.Results: A total of 556 clones were sequenced from the cDNA libraries used to construct the arrays. These cDNAs represented 175 singletons and 62 contigs, resulting in 237 unique putative genes. The gene sequences were classified into the following biological functions: cuticular proteins associated with arthropod exoskeletons, farnesoic acid O-methyltransferase (FaMeT), proteins belonging to the hemocyanin gene family, lectins, proteins relevant to lipid metabolism, mitochondrial proteins, muscle related proteins, phenoloxidase activators and ribosomal proteins. Moult cycle-related differential expression patterns were observed for many transcripts. Of particular interest were those relating to the formation and hardening of the exoskeleton, and genes associated with cell respiration and energy metabolism.Conclusions: The expression data presented here provide a chronological depiction of the molecular events associated with the biological changes that occur during the crustacean moult cycle. Tracing the temporal expression patterns of a large variety of transcripts involved in the moult cycle of P. pelagicus can provide a greater understanding of gene function, interaction, and regulation of both known and new genes with respect to the moulting process