23,454 research outputs found
Novelty and Collective Attention
The subject of collective attention is central to an information age where
millions of people are inundated with daily messages. It is thus of interest to
understand how attention to novel items propagates and eventually fades among
large populations. We have analyzed the dynamics of collective attention among
one million users of an interactive website -- \texttt{digg.com} -- devoted to
thousands of novel news stories. The observations can be described by a
dynamical model characterized by a single novelty factor. Our measurements
indicate that novelty within groups decays with a stretched-exponential law,
suggesting the existence of a natural time scale over which attention fades
Spreading and shortest paths in systems with sparse long-range connections
Spreading according to simple rules (e.g. of fire or diseases), and
shortest-path distances are studied on d-dimensional systems with a small
density p per site of long-range connections (``Small-World'' lattices). The
volume V(t) covered by the spreading quantity on an infinite system is exactly
calculated in all dimensions. We find that V(t) grows initially as t^d/d for
t>t^*$,
generalizing a previous result in one dimension. Using the properties of V(t),
the average shortest-path distance \ell(r) can be calculated as a function of
Euclidean distance r. It is found that
\ell(r) = r for r<r_c=(2p \Gamma_d (d-1)!)^{-1/d} log(2p \Gamma_d L^d), and
\ell(r) = r_c for r>r_c.
The characteristic length r_c, which governs the behavior of shortest-path
lengths, diverges with system size for all p>0. Therefore the mean separation s
\sim p^{-1/d} between shortcut-ends is not a relevant internal length-scale for
shortest-path lengths. We notice however that the globally averaged
shortest-path length, divided by L, is a function of L/s only.Comment: 4 pages, 1 eps fig. Uses psfi
Watch Out for the Beast: Fear Information and Attentional Bias in Children
Although valenced information about novel animals changes the implicit and explicit fear beliefs of children (Field & Lawson, 2003), how it might lead to anxiety is unknown. One possibility, based on cognitive models of anxiety, is that fear information creates attentional biases similar to those seen in anxiety disorders. Children between 7 and 9 years old were given positive information about 1 novel animal, negative information about another, and no information about the 3rd. A pictorial dot-probe task was used, immediately or with a 24-hr delay, to test for attentional biases to the different animals. The results replicated the finding that fear information changes children's fear beliefs. Regardless of whether there was a delay, children acquired an attentional bias in the left visual field toward the animal about which they held negative beliefs compared to the control animal. These results imply a possible way in which fear information might contribute to acquired fear
Superburst oscillations: ocean and crustal modes excited by Carbon-triggered Type I X-ray bursts
Accreting neutron stars (NS) can exhibit high frequency modulations in their
lightcurves during thermonuclear X-ray bursts, known as burst oscillations. The
frequencies can be offset from the spin frequency of the NS by several Hz, and
can drift by 1-3 Hz. One possible explanation is a mode in the bursting ocean,
the frequency of which would decrease (in the rotating frame) as the burst
cools, hence explaining the drifts. Most burst oscillations have been observed
during H/He triggered bursts, however there has been one observation of
oscillations during a superburst; hours' long Type I X-ray bursts caused by
unstable carbon burning deeper in the ocean. This paper calculates the
frequency evolution of an oceanic r-mode during a superburst. The rotating
frame frequency varies during the burst from 4-14 Hz, and is sensitive to the
background parameters, in particular the temperature of the ocean and ignition
depth. This calculation is compared to the superburst oscillations observed on
4U-1636-536. The predicted mode frequencies ( 10 Hz) would require a spin
frequency of 592 Hz to match observations; 6 Hz higher than the spin
inferred from an oceanic r-mode model for the H/He triggered burst
oscillations. This model also over-predicts the frequency drift during the
superburst by 90 %.Comment: Accepted for publication in MNRA
Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia
The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI) (LA) on plasma levels of pentraxin 3 (PTX3), an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(a)lipoproteinemia and angiographically defined atherosclerosis/coronary artery disease. Eleven patients, aged 55 ± 9.3 years (mean ± SD), were enrolled in the study. PTX3 soluble protein levels in plasma were unchanged by 2 sessions of LA; however, a downregulation of mRNA expression for PTX3 was observed, starting with the first session of LA (p < 0.001). The observed reduction was progressively increased in the interval between the first and second LA sessions to achieve a maximum decrease by the end of the second session. A statistically significantly greater treatment-effect correlation was observed in patients undergoing weekly treatments, compared with those undergoing treatment every 15 days. A progressive reduction in plasma levels of C-reactive protein was also seen from the first session of LA, with a statistically significant linear correlation for treatment-effect in the change in plasma levels of this established inflammatory marker (R(2) = 0.99; p < 0.001). Our findings suggest that LA has anti-inflammatory and endothelium protective effects beyond its well-established efficacy in lowering apoB100-containing lipoproteins
Screening for familial hypercholesterolaemia in primary care: Time for general practice to play its part
Fifty per cent of first-degree relatives of index cases with familial hypercholesterolemia (FH) inherit the disorder. Despite cascade screening being the most cost-effective method for detecting new cases, only a minority of individuals with FH are currently identified. Primary care is a key target area to increase identification of new index cases and initiate cascade screening, thereby finding close relatives of all probands. Increasing public and health professional awareness about FH is essential.
In the United Kingdom and in Australia, most of the population are reviewed by a General Practitioner (GP) at least once over a three-year period, offering opportunities to check for FH as part of routine clinical consultations. Such opportunistic approaches can be supplemented by systematically searching electronic health records with information technology tools that identify high risk patients. GPs can help investigate and implement results of this data retrieval.
Current evidence suggests that early detection of FH and cascade testing meet most of the criteria for a worthwhile screening program. Among heterozygous patients the long latent period before the expected onset of coronary artery disease provides an opportunity for initiating effective drug and lifestyle changes. The greatest challenge for primary care is to implement an efficacious model of care that incorporates sustainable identification and management pathways
Evidence from satellite altimetry for small-scale convection in the mantle
Small scale convection can be defined as that part of the mantle circulation in which upwellings and downwellings can occur beneath the lithosphere within the interiors of plates, in contrast to the large scale flow associated with plate motions where upwellings and downwellings occur at ridges and trenches. The two scales of convection will interact so that the form of the small scale convection will depend on how it arises within the large scale flow. Observations based on GEOS-3 and SEASAT altimetry suggest that small scale convection occurs in at least two different ways
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