31,519 research outputs found

    Constraints on Neutron Star Crusts From Oscillations in Giant Flares

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    We show that the fundamental seismic shear mode, observed as a quasi-periodic oscillation in giant flares emitted by highly-magnetized neutron stars, is particularly sensitive to the nuclear physics of the crust. The identification of an oscillation at ~ 30 Hz as the fundamental crustal shear mode requires a nuclear symmetry energy that depends very weakly on density near saturation. If the nuclear symmetry energy varies more strongly with density, then lower frequency oscillations, previously identified as torsional Alfven modes of the fluid core, could instead be associated with the crust. If this is the case, then future observations of giant flares should detect oscillations at around 18 Hz. An accurate measurement of the neutron skin thickness of lead will also constrain the frequencies predicted by the model.Comment: 5 pages, 3 figures; Version to appear in Phys. Rev. Let

    Modelling and simulation of a biomimetic underwater vehicle

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    This paper describes work carried out at the University of Glasgow investigating biomimetic fish-like propulsion systems for underwater vehicles. The development of a simple mathematical model is described for a biomimetic fish like vehicle which utilizes a tendon drive propulsion system. This model is then compared with a model of a vehicle of similar size but with a propeller for main propulsion. Simulation results for both models are shown and compared

    Immediate versus water-storage performance of Class V flowable composite restoratives

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    Objectives The aims of this investigation were to clarify the effects of 24 h water-storage and finishing time on mechanical properties and marginal adaptation to a Class V cavity of eight modern flowable resin-composites. Methods Eight flowable composites, plus two controls (one microfilled and one hybrid composite), were investigated with specimen sub-groups (n = 10) for each property measured. The principal series of experiments was conducted in model Class V cavities with interfacial polishing either immediately (3 min) after setting or after 24 h water-storage. After the finishing procedure, each tooth was sectioned in a buccolingual direction through the center of the restoration, and the presence or absence of marginal-gaps was measured (and then summed for each cavity) at 14 points (each 0.5 mm apart) along the cavity restoration interface (n = 10 per group; total points measured = 140). The shear bond-strengths to enamel and to dentin, and flexural strengths and moduli data were also measured at 3 min and after 24 h water-storage. Results For all flowable composites, polished immediately after setting, 14–30 summed gaps were observed (controls: 64 and 42). For specimens polished after 24 h, a significantly (p &#60; 0.05) reduced number of 8–17 summed gaps occurred for only 3 flowable composites; whereas for 5 flowable composites there were non-significantly-different (p &#62; 0.05) numbers (11–17) of summed gaps (controls: 28 and 22). After 24 h storage, shear bond-strengths to enamel and to dentin, flexural strengths and moduli increased highly significantly (p &#60; 0.001) for all materials, except Silux Plus. Significance A post-cure interval of 24 h resulted in enhanced mechanical and adhesive properties of flowable dental composites. In a minority of cases there was also a reduced incidence of marginal-gap formation. However the latter effect may be partly attributed to 24 h delayed polishing, even though such a delay is not usual clinical practice.</p

    Experience of domestic violence by women attending an inner city accident and emergency department.

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    OBJECTIVES: To identify the prevalence of domestic violence (DV) (defined as physical abuse perpetrated by intimate partners) in women attending an inner city accident and emergency department and to elicit women's response about being asked routinely about domestic violence in this setting. METHODS: 22 nursing shifts were purposefully sampled to be representative of day, night, and weekends. A questionnaire was administered to 198 consenting women who were not intoxicated, confused, or critically ill. RESULTS: The prevalence of acute trauma in women attributable to DV was 1% (95%CI 0.14 to 3.6), the prevalence of lifetime physical abuse was 34.8% (95%CI 28.2 to 41.5), of past year physical abuse was 6.1% (95%CI 3.2 to 10.3), and of lifetime life threatening physical abuse was 10.6% (95%CI 6.3 to 14.9). Seventy six per cent of women felt comfortable about being asked about DV and 60.5% of women felt that they should always or usually be asked about DV in this setting. CONCLUSION: This cross sectional survey adds to the body of knowledge showing that the prevalence of DV in women attending an accident and emergency department is high. Most women were in favour of being asked, and disclosure was associated with discomfort in few women. This sensitive area of history taking and referral could be undertaken by health professionals using a supportive approach

    Spatial clusters of gonorrhoea in England with particular reference to the outcome of partner notification: 2012 and 2013

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    Background: This study explored spatial-temporal variation in diagnoses of gonorrhoea to identify and quantify endemic areas and clusters in relation to patient characteristics and outcomes of partner notification (PN) across England, UK. Methods: Endemic areas and clusters were identified using a two-stage analysis with Kulldorff’s scan statistics (SaTScan). Results Of 2,571,838 tests, 53,547 diagnoses were gonorrhoea positive (positivity = 2.08%). The proportion of diagnoses in heterosexual males was 1.5 times that in heterosexual females. Among index cases, men who have sex with men (MSM) were 8 times more likely to be diagnosed with gonorrhoea than heterosexual males (p<0.0001). After controlling for age, gender, ethnicity and deprivation rank, 4 endemic areas were identified including 11,047 diagnoses, 86% of which occurred in London. 33 clusters included 17,629 diagnoses (34% of total diagnoses in 2012 and 2013) and spanned 21 locations, some of which were dominated by heterosexually acquired infection, whilst others were MSM focused. Of the 53,547 diagnoses, 14.5% (7,775) were the result of PN. The proportion of patients who attended services as a result of PN varied from 0% to 61% within different age, gender and sexual orientation cohorts. A third of tests resulting from PN were positive for gonorrhoea. 25% of Local Authorities (n = 81, 95% CI: 20.2, 29.5) had a higher than expected proportion for female PN diagnoses as compared to 16% for males (n = 52, 95% CI: 12.0, 19.9). Conclusions: The English gonorrhoea epidemic is characterised by spatial-temporal variation. PN success varied between endemic areas and clusters. Greater emphasis should be placed on the role of PN in the control of gonorrhoea to reduce the risk of onward transmission, re-infection, and complications of infection

    Forebody and vertical stabilizer effects on directional stability of a reusable LOX/RP (061) booster AR 12161-2

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    Results are presented of a wind tunnel test on the directional stability of space shuttle booster configurations. The test was conducted at the 14-inch trisonic tunnel starting 6 December 1971 and continued through 11 December 1971 for a total of 66 occupancy hours. Configurations tested included a cylindrical body with two axisymmetrical noses, one with and without canopy, one delta wing, located in two positions, five vertical tails (including a V tail), two having split rudders, ventral fins, two sets of chines, three airbreathing engine pods, and rocket engine shrouds. The model scale was 0.003366

    Magnetar giant flare high-energy emission

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    High energy (>250> 250 keV) emission has been detected persisting for several tens of seconds after the initial spike of magnetar giant flares. It has been conjectured that this emission might arise via inverse Compton scattering in a highly extended corona generated by super-Eddington outflows high up in the magnetosphere. In this paper we undertake a detailed examination of this model. We investigate the properties of the required scatterers, and whether the mechanism is consistent with the degree of pulsed emission observed in the tail of the giant flare. We conclude that the mechanism is consistent with current data, although the origin of the scattering population remains an open question. We propose an alternative picture in which the emission is closer to that star and is dominated by synchrotron radiation. The RHESSIRHESSI observations of the December 2004 flare modestly favor this latter picture. We assess the prospects for the Fermi Gamma-Ray Space Telescope to detect and characterize a similar high energy component in a future giant flare. Such a detection should help to resolve some of the outstanding issues.Comment: 20 pages, 14 figure

    Social Policy Interventions to Enhance the HIV/AIDS Response in Sub-Saharan Africa

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    Asymptotically scale-invariant occupancy of phase space makes the entropy Sq extensive

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    Phase space can be constructed for NN equal and distinguishable subsystems that could be (probabilistically) either {\it weakly} (or {\it "locally"}) correlated (e.g., independent, i.e., uncorrelated), or {\it strongly} (or {\it globally}) correlated. If they are locally correlated, we expect the Boltzmann-Gibbs entropy SBGkipilnpiS_{BG} \equiv -k \sum_i p_i \ln p_i to be {\it extensive}, i.e., SBG(N)NS_{BG}(N)\propto N for NN \to\infty. In particular, if they are independent, SBGS_{BG} is {\it strictly additive}, i.e., SBG(N)=NSBG(1),NS_{BG}(N)=N S_{BG}(1), \forall N. However, if the subsystems are globally correlated, we expect, for a vast class of systems, the entropy Sqk[1ipiq]/(q1)S_q\equiv k [1- \sum_i p_i^q]/(q-1) (with S1=SBGS_1=S_{BG}) for some special value of q1q\ne1 to be the one which extensive (i.e., Sq(N)NS_q(N)\propto N for NN \to\infty).Comment: 15 pages, including 9 figures and 8 Tables. The new version is considerably enlarged with regard to the previous ones. New examples and new references have been include

    Evolutionary descent of prion genes from a ZIP metal ion transport ancestor

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    In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic. Insights into the function of PrP may be obtained through a characterization of its molecular neighborhood. Quantitative interactome data revealed the spatial proximity of a subset of metal ion transporters of the ZIP family to mammalian prion proteins. A subsequent bioinformatic analysis revealed the presence of a prion-like protein sequence within the N-terminal, extracellular domain of a phylogenetic branch of ZIPs. Additional structural threading and ortholog sequence alignment analyses consolidated the conclusion that the prion protein gene family is phylogenetically derived from a ZIP-like ancestor molecule. Our data explain structural and functional features found within mammalian prion proteins as elements of an ancient involvement in the transmembrane transport of divalent cations. The connection to ZIP proteins is expected to open new avenues to elucidate the biology of the prion protein in health and disease
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