A critical assessment of marine aquarist biodiversity data and commercial aquaculture:identifying gaps in culture initiatives to inform local fisheries managers

It is widely accepted that if well managed, the marine aquarium trade could provide socio-economic stability to local communities while incentivising the maintenance of coral reefs. However, the trade has also been implicated as having potentially widespread environmental impacts that has in part driven developments in aquaculture to relieve wild collection pressures. This study investigates the biodiversity in hobbyist aquaria (using an online survey) and those species currently available from an aquaculture source (commercial data and hobbyist initiatives) in the context of a traffic light system to highlight gaps in aquaculture effort and identify groups that require fisheries assessments. Two hundred and sixty nine species including clown fish, damsels, dotty backs, angelfish, gobies, sea horses and blennies, have reported breeding successes by hobbyists, a pattern mirrored by the European and US commercial organisations. However, there is a mismatch (high demand and low/non-existent aquaculture) for a number of groups including tangs, starfish, anemones and hermit crabs, which we recommend are priority candidates for local stock assessments. Hobbyist perception towards the concept of a sustainable aquarium trade is also explored with results demonstrating that only 40% of respondents were in agreement with industry and scientists who believe the trade could be an exemplar of a sustainable use of coral reefs. We believe that a more transparent evidence base, including the publication of the species collected and cultured, will go some way to align the concept of a sustainable trade across industry stakeholders and better inform the hobbyist when purchasing their aquaria stock. We conclude by proposing that a certification scheme established with government support is the most effective way to move towards a self-regulating industry. It would prevent industry "greenwashing" from multiple certification schemes, alleviate conservation concerns, and, ultimately, support aquaculture initiatives alongside well managed ornamental fisheries

Tensile strength of simulated and welded butt joints in W-Cu composite sheet

The weldability of W-Cu composite sheet was investigated using simulated and welded joints. The welded joints were produced in a vacuum hot press. Tensile test results showed that simulated joints can provide strength and failure mode data which can be used in joint design for actual weldments. Although all of the welded joints had flaws, a number of these joints were as strong as the W-Cu composite base material

Signalling C-Type lectin receptors, microbial recognition and immunity

This work was supported in part by the Wellcome Trust, Medical Research Council (UK) and the University of Cape Town. J.C. Hoving is a Carnegie Corporation postdoctoral researcher at the University of Cape Town. We apologize of all our colleagues whose important contributions we could not cite due to space constraints.Peer reviewedPublisher PD

Is the PAMELA Positron Excess Winos?

Recently the PAMELA satellite-based experiment reported an excess of galactic positrons that could be a signal of annihilating dark matter. The PAMELA data may admit an interpretation as a signal from a wino-like LSP of mass about 200 GeV, normalized to the local relic density, and annihilating mainly into W-bosons. This possibility requires the current conventional estimate for the energy loss rate of positrons be too large by roughly a factor of five. Data from anti-protons and gamma rays also provide tension with this interpretation, but there are significant astrophysical uncertainties associated with their propagation. It is not unreasonable to take this well-motivated candidate seriously, at present, in part because it can be tested in several ways soon. The forthcoming PAMELA data on higher energy positrons and the FGST (formerly GLAST) data, should provide important clues as to whether this scenario is correct. If correct, the wino interpretation implies a cosmological history in which the dark matter does not originate in thermal equilibrium.Comment: 7 pages, 4 figue

More on the Narrowing of Impact Broadened Radio Recombination Lines at High Principal Quantum Number

Recently Alexander and Gulyaev have suggested that the apparent decrease in impact broadening of radio recombination lines seen at high principal quantum number n may be a product of the data reduction process, possibly resulting from the presence of noise on the telescope spectra that is not present on the calculated comparison spectra. This is an interesting proposal. However, there are serious problems with their analysis that need to be pointed out. Perhaps the most important of these is the fact that for principal quantum numbers below n = 200, where the widths are not in question, their processed generated profile widths do not fit the widths of the processed lines obtained at the telescope. After processing, the halfwidths of the generated and telescope profiles must agree below n = 200 if we are to believe that the processed generated linewidths above n = 200 are meaningful. Theirs do not. Furthermore, we find that after applying the linewidth reduction factors found by Alexander and Gulyaev for their noise added profiles to our generated profiles to simulate their noise adding effect, the processed widths we obtain still do not come close to explaining the narrowing seen in the telescope lines for n values in the range 200 < n < 250. It is concluded that what is needed to solve this mystery is a completely new approach using a different observing technique instead of simply a further manipulation of the frequency-switched data.Comment: Six pages with 4 figures. Accepted for publication in Astrophysics and Space Scienc

Neutralino Dark Matter from Indirect Detection Revisited

We revisit indirect detection possibilities for neutralino dark matter, emphasizing the complementary roles of different approaches. While thermally produced dark matter often requires large astrophysical "boost factors" to observe antimatter signals, the physically motivated alternative of non-thermal dark matter can naturally provide interesting signals, for example from light wino or Higgsino dark matter. After a brief review of cosmic ray propagation, we discuss signals for positrons, antiprotons, synchrotron radiation and gamma rays from wino annihilation in the galactic halo, and examine their phenomenology. For pure wino dark matter relevant to the LHC, PAMELA and GLAST should report signals.Comment: 23 pages, 9 figures: v2. Corrected typos, fixed synchrotron bounds in light of bugs in progra

Renewing the Exploration Approach for Mid-Enthalpy Systems: Examples from Northern England and Scotland

After a promising start in the 1970s and 80s, the UK rather fell behind other countries in the search for viable mid-enthalpy geothermal resources. This situation began to turn around in 2004, when the first of three deep geothermal exploration boreholes were drilled in northern England. What distinguished these from earlier drilling in Cornwall was the deliberate search for naturallyhigh permeability associated with major faults, especially those that have undergone strike-slip reactivation during the Cenozoic. Boreholes at Eastgate in the North Pennines targeted buried radiothermal granite, whereas the 1,821m-deep Science Central Borehole in Newcastle upon Tyne targeted a postulated deep sedimentary aquifer (the Fell Sandstones), which were inferred to be connected laterally to the granitic heat source by a major fault (the reactivation of the Iapetus geo-suture). The drilling was in both cases rewarded with impressive heat flows, and in the case of Eastgate with what is believed to be the highest permeability yet found in a deep granite batholith anywhere in the world. In parallel with these developments, a re-assessment was made of the preexisting geothermal heat flow database for the UK, applying newly-standardised correction protocols for palaeoclimatic and topographic distortions, which were found to be particularly marked in Scotland (where only shallow boreholes had been used to establish geothermal gradients in the original 1980s analysis), Similar prospects in northern England (similar to that drilled at Science Central) are now the focus of commercial exploration efforts. Appraisal of fault dispositions relative to the present-day maximum compressive stress azimuth are being used to identify the most promising areas for intersecting fault-related permeability at depth. New geophysical tools – most notably atomic dielectric resonance scanning – are also being appraised for their ability to directly detect features (such as hot brines) which are indicative of localised convection in target fault zones and aquifers

Risk and protective factors for transgender youths' substance use.

Research at the intersection of substance use and protective factors among transgender youth is scarce; emerging evidence suggests high risk for substance use for transgender youth. We analyzed data from 323 transgender youth aged 14-18 (Mₐₑ = 16.67) to investigate the extent that risk (enacted stigma) and protective factors (support from family, school, friends) were related to substance use (i.e., cannabis and tobacco use, binge drinking). Enacted stigma was linked to higher odds of substance use behaviors, family connectedness was related to lower levels of tobacco and cannabis use, and more than one protective factor significantly lowered the probability of engaging in substance use behaviors. Support from multiple sources may be differentially protective against substance use for transgender youth

Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in doberman pinschers with preclinical dilated cardiomyopathy (the PROTECT study)

&lt;p&gt;Background: The benefit of pimobendan in delaying the progression of preclinical dilated cardiomyopathy (DCM) in Dobermans is not reported.&lt;/p&gt; &lt;p&gt;Hypothesis: That chronic oral administration of pimobendan to Dobermans with preclinical DCM will delay the onset of CHF or sudden death and improve survival.&lt;/p&gt; &lt;p&gt;Animals: Seventy-six client-owned Dobermans recruited at 10 centers in the UK and North America.&lt;/p&gt; &lt;p&gt;Methods: The trial was a randomized, blinded, placebo-controlled, parallel group multicenter study. Dogs were allocated in a 1:1 ratio to receive pimobendan (Vetmedin capsules) or visually identical placebo.&lt;/p&gt; &lt;p&gt;The composite primary endpoint was prospectively defined as either onset of CHF or sudden death. Time to death from all causes was a secondary endpoint.&lt;/p&gt; &lt;p&gt;Results: The proportion of dogs reaching the primary endpoint was not significantly different between groups (P = .1). The median time to the primary endpoint (onset of CHF or sudden death) was significantly longer in the pimobendan (718 days, IQR 441–1152 days) versus the placebo group (441 days, IQR 151–641 days) (log-rank P = 0.0088). The median survival time was significantly longer in the pimobendan (623 days, IQR 491–1531 days) versus the placebo group (466 days, IQR 236–710 days) (log-rank P = .034).&lt;/p&gt; &lt;p&gt;Conclusion and Clinical Importance: The administration of pimobendan to Dobermans with preclinical DCM prolongs the time to the onset of clinical signs and extends survival. Treatment of dogs in the preclinical phase of this common cardiovascular disorder with pimobendan can lead to improved outcome.&lt;/p&gt