ショウガッコウ サンスウカ ノ モンダイ カイケツ カテイ ニ オケル ハッケン ホウ heuristics ニ ツイテ ノ ケンキュウ

Orientador: Prof. Dr. Alvino MoserDissertação (mestrado) - Universidade Federal do Paraná, Setor de Educação, Programa de Pós-Graduação em EducaçãoInclui referências: p. 127-131Resumo: A formação profissional do cirurgião-dentista enfatiza o tecnicismo e não apresenta conteúdos didáticos para a capacitação no relacionamento interpessoal. Este trabalho busca apresentar em que nível de entendimento e informação se processa o relacionamento do estagiário com o paciente; compará-lo com o relacionamento do profissional em exercício há mais de cinco anos, com o intuito de verificar as mudanças do relacionamento interpessoal que ocorreram após um período de tempo no exercício da profissão. Ficaram demonstradas as diferenças existentes nas três populações envolvidas na pesquisa. O universo de entendimento frente a um a mesma ação odontológica varia segundo o entendimento dos pacientes, profissionais e estagiários. Os itens mais significativos são indicados como subsídios para a reforma do currículo de Odontologia, Ficando explícita a necessidade de um currículo com conteúdos formadores ou centrados no relacionamento interpessoal. Desta forma, ficará compensada a diferença excessiva da carga horária de disciplinas essencialmente técnicas, em relação à carga horária das disciplinas humanísticas. Trata-se de qualificar o profissional como técnico e como ser de relações empáticas.Abstract: A dentist professional formation gives emphasis to the technicist elements, while its contents related to the process of learning, are kept away. This dissertation tries to put up the relationship of an intern-dentist with his patient, to compare it with a five years dentist experience in order to cheek up the changes during his professional practice, Some differences were found among the responding populations to the research, as the following: one same dentistry action received varied responses; coming from the professional dentists, coming from the patients and coming from the dentists holding practice. Those responses are being indicated significantly as elements for a possible reformulation of their curriculum centred onwards on their interpersonal relationship, in this way the exceeding hours in the technic matters will be exchanged with those fulfilling empathic relationship standards

The Inhibitory Effect of Conjugated and Polyunsaturated Fatty Acids on the Growth of Human Cancer Cell Lines

arachidonic acidconjugated fatty acidcytotoxicitydocosahexaenoic acideicosapentaenoic acidhuman cancer cerllpolyunsaturated fatty aci

非線形性を考慮したフリーク波の数値的再現

学位の種別: 課程博士審査委員会委員 : （主査）東京大学教授 早稲田 卓爾, 東京大学教授 高木 健, 東京大学教授 林 昌奎, 東京大学教授 山本 昌宏, 岐阜大学教授 田中 光宏University of Tokyo(東京大学

Activation of PPARγ inhibits cell growth and induces apoptosis in human gastric cancer cells

AbstractWe investigated the expression of peroxisome proliferator-activated receptor γ (PPARγ) and the role of PPARγ in cell growth in human gastric cancer cells. Reverse transcription-polymerase chain reaction, Northern blot and Western blot analyses showed that a human gastric cancer cell line, MKN45, expressed PPARγ mRNA and protein. Luciferase assay in MKN45 cells showed that troglitazone, a selective ligand for PPARγ, transactivated the transcription of a peroxisome proliferator response element-driven promoter. Troglitazone or pioglitazone, selective ligands for PPARγ, inhibited the growth of MKN45 cells in a dose-dependent manner. Co-incubation of MKN45 cells with troglitazone induced DNA ladder formation. These results suggest that human gastric cancer cells express PPARγ and that activation of PPARγ inhibits cell growth and induces apoptosis in gastric cancer cells

Expression of retinoic acid receptor genes in keratinizing front of skin

AbstractWe found, by an in situ hybridization method with riboprobes synthesized from human cDNA of the retinoic acid receptor (RAR), that the RAR genes (predominantly γ-subtype) are intensively expressed in the epidermis of normal and psoriasic human skins, and also in keratinizing fronts of 4-day-old mouse skins, nail matrices and hair follicles. Thus, target cells of retinoic acid in the skins are concluded to be keratinocytes, which is quite consistent with the fact that retinoic acid regulates keratinization of epidermis in vivo and also modulates expression of the keratin gene in vitro