Diaqua­bis(2,4-dichloro-6-formyl­phenolato)zinc(II)–bis­(μ-2,4-dichloro-6-formyl­phenolato)bis­[aqua­(2,4-dichloro-6-formyl­phenolato)zinc(II)] (2/1)

The crystal of the title compound, [Zn(C7H3Cl2O2)2(H2O)2]2·[Zn2(C7H3Cl2O2)4(H2O)2], consists of monomeric and dimeric ZnII complexes. Both complexes afford a six-coordinated coordination environment about the Zn atoms with cis-configuration ligands. The deprotonated hydr­oxy groups of the 3,5-dichloro­salicylaldehyde ligands bridge two metal cations, forming a centrosymmetric dimeric complex. Inter­molecular O—H⋯O hydrogen bonding occurs between the coordinated water mol­ecules and deprotonated hydr­oxy groups in the crystal structure

3次元ストレインエコーと電気解剖学的マッピングシステムを用いた、発作性心房細動患者における左房壁運動・基質異常の評価

内容の要旨 , 審査の要旨広島大学(Hiroshima University)博士(医学)Doctor of Philosophy in Medical Sciencedoctora

Sign change in c-axis thermal expansion and lattice collapse by Ni substitution in Co1-xNixZr2 superconductors

We investigated the structural, electronic, and superconducting properties of Co1-xNixZr2, in which c-axis thermal expansion is systematically controlled. At x (smaller than) 0.3, c-axis negative thermal expansion (NTE) was observed, and the thermal expansion constant {\alpha}c approached zero with increasing x. At x = 0.4-0.6, zero thermal expansion was observed, and positive thermal expansion (PTE) appeared for x (greater than) 0.7. By analyzing the c/a ratio, we observed a possible collapsed transition in the tetragonal lattice at around x = 0.6-0.8. The lattice collapse results in c-axis PTE and the suppression of bulk superconductivity.Comment: 16 pages, 5 figures, 1 table, Supporting material

Observation of superconductivity and enhanced upper critical field of η{\eta}-carbide-type oxide Zr4{_\mathrm{4}}Pd2_{\mathrm{2}}O

We report the first observation of bulk superconductivity of a ${\eta}$-carbide-type oxide Zr$_{4}$Pd$_{2}$O. The crystal structure and the superconducting properties were studied through synchrotron X-ray diffraction, magnetization, electrical resistivity, and specific heat measurement. The superconducting transition was observed at $T_{\mathrm{c}}$ = 2.73 K. Our measurement revealed that the ${\eta}$-carbide-type oxide superconductor Zr$_{4}$Pd$_{2}$O shows an enhanced upper critical field ${\mu_{\mathrm{0}}H_{\mathrm{c2}}\mathrm{(0)}}$ = 6.72 T, which violates the Pauli-Clogston limit ${\mu_{\mathrm{0}}H_{\mathrm{P}}}$ = 5.29 T. On the other hand, we found that the enhanced upper critical field is absent in a Rh analogue Zr$_{4}$Rh$_{2}$O. The large ${\mu_{\mathrm{0}}H_{\mathrm{c2}}\mathrm{(0)}}$ of Zr$_{4}$Pd$_{2}$O would be raised from strong spin-orbit coupling with Pd-4$d$ electrons. The discovery of new superconducting properties for Zr$_{4}$Pd$_{2}$O would shed light on the further development of ${\eta}$-carbide-type oxide superconductors.Comment: 12 pages, 4 figures, 3 table

Cross-breed comparisons identified a critical 591-kb region for bovine carcass weight QTL (CW-2) on chromosome 6 and the Ile-442-Met substitution in NCAPG as a positional candidate

<p>Abstract</p> <p>Background</p> <p>Growth-related traits have been mapped on bovine chromosome 6 (BTA 6) in various bovine breed populations. We previously mapped a significant quantitative trait locus (QTL) for carcass and body weight (<it>CW-2</it>) between 38 and 55 cM on BTA 6 using a Japanese Black half-sib family. Additional QTL mapping studies detected four QTL for body or carcass weight that overlapped with <it>CW-2 </it>in Japanese Black and Japanese Brown half-sib families. To map the region in greater detail, we applied cross-breed comparisons of haplotypes that have been shown to be powerful in canine.</p> <p>Results</p> <p>We used 38 microsatellite markers to search for a shared <it>Q </it>(increasing carcass and/or body weight) haplotype within the 17-cM <it>CW-2 </it>region among five sires. Linkage disequilibrium mapping using maternal alleles of the offspring showed that an 815-kb shared <it>Q </it>haplotype was associated with body or carcass weight in both breeds. The addition of 43 single nucleotide polymorphism (SNP) markers narrowed the region to 591 kb containing 4 genes. The SNP changing Ile-442 to Met in <it>NCAPG </it>(chromosome condensation protein G) was significantly associated with carcass weight (<it>p </it>< 1.2 × 10^-11) in a large Japanese Black population as well as in the five families. The <it>Q </it>allele of the SNP was also associated with a larger longissimus muscle area and thinner subcutaneous fat thickness in steers of all five families, indicating that the <it>CW-2 </it>locus is pleiotropic and favorable for marker-assisted selection of beef cattle.</p> <p>Conclusion</p> <p>A 591-kb critical region for <it>CW-2 </it>was identified. The SNP changing Ile-442 to Met in <it>NCAPG </it>(chromosome condensation protein G) can be used as a positional candidate of <it>CW-2 </it>for marker-assisted selection.</p

Mitochondria-specific RNA-modifying Enzymes Responsible for the Biosynthesis of the Wobble Base in Mitochondrial tRNAs

Human mitochondrial (mt) tRNALys has a taurine-containing modified uridine, 5-taurinomethyl-2-thiouridine (τm5s2U), at its anticodon wobble position. We previously found that the mt tRNALys, carrying the A8344G mutation from cells of patients with myoclonus epilepsy associated with ragged-red fibers (MERRF), lacks the τm5s2U modification. Here we describe the identification and characterization of a tRNA-modifying enzyme MTU1 (mitochondrial tRNA-specific 2-thiouridylase 1) that is responsible for the 2-thiolation of the wobble position in human and yeast mt tRNAs. Disruption of the yeast MTU1 gene eliminated the 2-thio modification of mt tRNAs and impaired mitochondrial protein synthesis, which led to reduced respiratory activity. Furthermore, when MTO1 or MSS1, which are responsible for the C5 substituent of the modified uridine, was disrupted along with MTU1, a much more severe reduction in mitochondrial activity was observed. Thus, the C5 and 2-thio modifications act synergistically in promoting efficient cognate codon decoding. Partial inactivation of MTU1 in HeLa cells by small interference RNA also reduced their oxygen consumption and resulted in mitochondria with defective membrane potentials, which are similar phenotypic features observed in MERRF.This work was supported by grants-in-aid for scientific research on priority areas from the Ministry of Education, Science, Sports, and Culture of Japan, and by a grant from the New Energy and Industrial Technology Development Organization (to T. S.)

Experimental characterization and performance improvement evaluation of an electromagnetic transducer utilizing a tuned inerter

This research reports on the experimental verification of an enhanced energy conversion device utilizing a tuned inerter called a tuned inertial mass electromagnetic transducer (TIMET). The TIMET consists of a motor, a rotational mass, and a tuning spring. The motor and the rotational mass are connected to a ball screw and the tuning spring interfaced to the ball screw is connected to the vibrating structure. Thus, vibration energy of the structure is absorbed as electrical energy by the motor. Moreover, the amplified inertial mass can be realized by rotating relatively small physical masses. Therefore, by designing the tuning spring stiffness and the inertial mass appropriately, the motor can rotate more effectively due to the resonance effect, leading to more effective energy generation. The authors designed a prototype of the TIMET and conducted tests to validate the effectiveness of the tuned inerter for electromagnetic transducers. Through excitation tests, the property of the hysteresis loops produced by the TIMET is investigated. Then a reliable analytical model is developed employing a curve fitting technique to simulate the behavior of the TIMET and to assess the power generation accurately. In addition, numerical simulation studies on a structure subjected to a seismic loading employing the developed model are conducted to show the advantages of the TIMET over a traditional electromagnetic transducer in both vibration suppression capability and energy harvesting efficiency

4-Phenyl­diazenyl-2-[(R)-(1-phenyl­ethyl)imino­meth­yl]phenol

The title chiral photochromic Schiff base compound, C21H19N3O, was synthesized from (R)-1-phenyl­ethyl­amine and the salicylaldehyde of an azobenzene derivative. The mol­ecule corresponds to the phenol–imine tautomer, the C=N and N—C bond distances being 1.279 (3) and 1.477 (3) Å, respectively. An intra­molecular O—H⋯N hydrogen bond occurs. The diazenyl group adopts a trans form with an N=N distance of 1.243 (3) Å