Pengaruh Kepuasan Kerja dan Komitmen Organisasi terhadap Prestasi Kerja Karyawan pada Dinas Perhubungan Komunikasi dan Informatika Kabupaten Agam

This study aims to reveal: 1) How does the influence of job satisfaction on employee performance Transport Department of Communication and Information Agam; 2) How does organisasit commitment on employee performance Transport Department of Communication and Information Agam; 3) How does the influence of job satisfaction and organisasit commitment on performance Department of Transportation employee Agam Communications and Information Technology.Object of study is the Department of Transportation employee Agam Communication and Information. The study population was all employees of the Department of Communication and Information Agam numbering 70 people. The data analysis technique used is multiple regression.Results of the study are: 1) There is a positive and significant effect between job satisfaction on job performance at the Department of Communication and Information Agam with regression coefficient 0.206. Means to increase employee performance can be done by improving the job satisfaction at the Department of Communication and Information Agam, 2) There is a positive and significant effect between organizational commitment on job performance at the Department of Communication and Information Agam with regression coefficient 0.109. Means to increase employee performance can be done by improving the organizations commitment to the Department of Transportation, Communication and Information Agam. To achieve high performance, the employee job satisfaction and organizational commitment of employees in Agam District should be improved. Keyword: Job Satisfaction, Organisasit Commitment, Employee Performance multiple regression

Cytotoxicity and variant cellular internalization behavior of water-soluble sulfonated nanographene sheets in liver cancer cells

Highly exfoliated sulfonated graphene sheets (SGSs), an alternative to graphene oxide and graphene derivatives, were synthesized, characterized, and applied to liver cancer cells in vitro. Cytotoxicity profiles were obtained using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, WST-1[2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, and lactate dehydrogenase release colorimetric assays. These particles were found to be non-toxic across the concentration range of 0.1 to 10 μg/ml. Internalization of SGSs was also studied by means of optical and electron microscopy. Although not conclusive, high-resolution transmission and scanning electron microscopy revealed variant internalization behaviors where some of the SGS became folded and compartmentalized into tight bundles within cellular organelles. The ability for liver cancer cells to internalize, fold, and compartmentalize graphene structures is a phenomenon not previously documented for graphene cell biology and should be further investigated

Unraveling diffusion and other shape selectivity effects in ZSM5 using n-Hexane hydroconversion single-event microKinetics

Potentially dominant factors governing the shape selectivity in n-hexane hydroconversion over a Pt/H-ZSM5 catalyst were evaluated by means of single-event microkinetic (SEMK) model regression against experimental data. The observed product distribution could be adequately modeled, and a corresponding physically meaningful interpretation could be made only when accounting for intracrystalline diffusion limitations for each hexane isomer involved in the reaction network, rather than considering physisorption effects or transition-state shape selectivity. Simultaneous diffusion and reaction inside the catalyst crystallites were expressed via Ficks second law, while the alkane Fick diffusion coefficients were assessed by explicitly accounting for mixture nonideality effects. A 3-fold lower diffusion coefficient was found to be required for 3-methylpentane compared with 2-methylpentane to explain the typically high selectivity toward the latter alkane. Once formed inside the catalyst crystallite, dimethylbutane isomers remained nearly immobile as was evident from their significantly lower diffusion coefficients. Reaction at the crystallite external surface was primarily responsible for the marginal conversion toward the former species, as observed experimentally