548 research outputs found
Participatory Irrigation Management and its Financial Viability: A Case Study
Water is a key input of agriculture. In the past, the area under cultivation was small and there was less stress on farmers to grow more and more of each crop. Water was considered a free good. The situation has changed since. The increase in cropping intensity has led to a rise in the demand for irrigation water. Water is not a free good any more. The provision of irrigation water to the farmer’s fields is going to be costlier. The Government of Pakistan is spending heavily on the operation and maintenance of the irrigation system yet shortage of funds is a major reason for deferred maintenance, which threatens the operational integrity of the irrigation system [World Bank (1988) and Haq (1995)]. The shortfall in O&M funding was estimated to be more than 24 percent in 1993 [World Bank (1994)]. As poor O&M has direct effect on the productivity of agriculture, indirectly it affects the whole economy [Carruthers (1981)]. The allocation of funds for the increasing O&M costs is becoming a problem for the Government of Pakistan with every successive year. One logical answer to this problem is to increase abiana1 fees from the users of irrigation water supplies. The revenue collected through abiana may be used for O&M purposes, but it has been reported that the revenue collection is far less than the expenditures incurred. Resultantly the gap has been increasing every year [Chaudhry (1989)]. This situation demands investigation of abiana recovery and increasing O&M costs to know the real situation which in turn will help in deciding whether it is feasible to divert the financing of O&M activities towards farmer organisations (completely or partially). This paper aims at estimating the present level of operation and maintenance expenditures of the H-4-R Distributary and the present situation of the abiana collection and the extent of its leakage through different means.
Flowfield-dependent variant method for moving-boundary problems
A novel numerical scheme using the combination of flowfield-dependent variation method and arbitrary Lagrangian–Eulerian method is developed. This method is a mixed explicit–implicit numerical scheme, and its implicitness is dependent on the physical properties of the flowfield. The scheme is discretized using the finite-volume method to give flexibility in dealing with complicated geometries. The formulation itself yields a sparse matrix, which can be solved by using any iterative algorithm. Several benchmark problems in two-dimensional inviscid and viscous flow have been selected to validate the method. Good agreement with available experimental and numerical data in the literature has been obtained, thus showing its promising application in complex fluid–structure interaction problems
Estimation and separation of N-acetyl-beta-D-glucosaminidase isoenzymes in urine
N-acetyl-beta-D-glucosaminidase is a lysosomal enzyme made up of two isoenzymes (A and B). It has been used extensively as a marker for kidney damage. However, its estimation in urine has not been standardized. We have established a method for the estimation and separation of NAG isoenzymes by ion-exchange chromatography. In 19 experiments done so far, this method has given reproducible results. The significance of this method is that with a single experiment, one can estimate total as well as individual isoenzyme activity. Furthermore, urine constituents do not appear to interfere in this assay
Participatory Irrigation Management and its Financial Viability: A Case Study
Water is a key input of agriculture. In the past, the area
under cultivation was small and there was less stress on farmers to grow
more and more of each crop. Water was considered a free good. The
situation has changed since. The increase in cropping intensity has led
to a rise in the demand for irrigation water. Water is not a free good
any more. The provision of irrigation water to the farmer’s fields is
going to be costlier. The Government of Pakistan is spending heavily on
the operation and maintenance of the irrigation system yet shortage of
funds is a major reason for deferred maintenance, which threatens the
operational integrity of the irrigation system [World Bank (1988) and
Haq (1995)]. The shortfall in O&M funding was estimated to be more
than 24 percent in 1993 [World Bank (1994)]. As poor O&M has direct
effect on the productivity of agriculture, indirectly it affects the
whole economy [Carruthers (1981)]. The allocation of funds for the
increasing O&M costs is becoming a problem for the Government of
Pakistan with every successive year. One logical answer to this problem
is to increase abiana1 fees from the users of irrigation water supplies.
The revenue collected through abiana may be used for O&M purposes,
but it has been reported that the revenue collection is far less than
the expenditures incurred. Resultantly the gap has been increasing every
year [Chaudhry (1989)]
Urinary N-acetyl-beta-D-glucosaminidase in rheumatoid arthritis
Excretion of urinary N-acetyl beta-D-glucosaminidase (NAG) and its isoenzyme patterns were studied in two groups of patients with rheumatoid arthritis (RA) and in normal control subjects. Urine samples were collected from 30 seropositive RA patients, 19 seronegative RA patients, and 15 normal healthy subjects. All the patients and normal subjects were assessed to have normal liver and kidney functions. A small portion of the urine sample was dialyzed against 0.01 M phosphate buffer, pH 7.0 and NAG activity was monitored. Mean +/- SD values of urinary NAG in seropositive RA patients, in seronegative RA patients and in normal healthy subjects were found to be 4.20 +/- 3.73 U/g creatinine, 2.96 +/- 2.11 U/gm creatinine, and 1.71 +/- 0.6 U/g creatinine, respectively. The mean urinary, NAG value in RA patients was found to be significantly higher (P \u3c 0.05) in seropositive RA compared to the mean NAG value in normal healthy subjects and patients with seronegative RA when analyzed by one way ANOVA and Tukey-HSD test. The mean proportion of isoenzyme form B to isoenzyme form A in seropositive RA patients was also found to be significantly different (P \u3c 0.05) from the mean proportion of these forms in normal healthy subjects and seronegative RA patients. There also appears to be a correlation between the concentration of urinary NAG and severity of the disease in seropositive RA
Banti\u27s syndrome: case report and review of literature.
In 1898 Banti described a disorder characterized by splenomegaly and hypersplenism, resulting in portal hypertension and anemia in the absence of hematological disease. 1 Banti\u27s syndrome is also known as non-cirrhotic portal hypertension (NCPH) in India and Idiopathic Portal Hypertension (IPH) in Japan. Hepatoportal sclerosis seems to be its counterpart in the United States. 2,3 Banti\u27s syndrome is a disorder of unknown etiology, clinically characterized by portal hypertension (varices and portosystemic collateral vessels), splenomegaly, and anemia (hypersplenism). 3 It has been reported from Indian subcontinent. 4-6 In a Pakistani case series of portal hypertension, 18 out of 37 patients were found to have IPH as the etiology. 6 We report a case of Banti\u27s syndrome in an 20-year old girl presenting to us with anemia and splenomegaly
Heterogeneity of methotrexate binding in human colon tumor cells
[3H]-methotrexate binding at pH 5.0 and pH 7.2 by the cytosol of tumor tissues and the surrounding normal areas of the gastrointestinal tract of patients suffering from colon or gastric cancer has been used to identify in these cells the presence of a binder of methotrexate having low-affinity for this drug in addition to the enzyme dihydrofolate reductase. Scatchard analysis of the [3H]-methotrexate binding data by a colon tumor sample also reveals that there are two binders of this drug present in the cytosol of these cells. The association constant (Kass) for one binder of methotrexate is = 5.6 x 10(7) M-1 while the Kass for the second binder is = 1.0 x 10(6) M-1. The two binders do not differ very much in their apparent molecular weight. Upon isoelectric focusing, the tumor cell cytosol resolves into 4 major isoproteins each having the ability not only to bind [3H]-methotrexate but also reduce [3H]-pteroylglutamic acid to [3H]-tetrahydropteroylglutamic acid. This suggests that the two binders of methotrexate may be the two forms of dihydrofolate reductase having different affinities for this anticancer drug
Unsteady slip flow of amicropolarnanofluid over an impulsively stretched vertical surface
The unsteady mixed convective flow of micropolarnanofluid over an impulsively stretched vertical surface has been examined. A model has been developed to analyze the behavior of nanofluids in presentmicropolar fluids studied numerically for both cases of assisting and opposing flow taking into account the thermal convective boundary condition. A model has been developed to analyze the behavior of nanofluids containing metallic nanoparticles as copper (Cu)and nonmetallic nanoparticles as alumina (A in water-micropolarnanofluidhave been considered. The governing partial differential equations have been transformed to non-similar differential equations then have been solved numerically by using theRunge-Kutta-Fehlberg method of seventh order (RKF7). The results have been compared with the published results and are found in excellent agreement
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