Learning Emotion Representations from Verbal and Nonverbal Communication

Emotion understanding is an essential but highly challenging component of artificial general intelligence. The absence of extensively annotated datasets has significantly impeded advancements in this field. We present EmotionCLIP, the first pre-training paradigm to extract visual emotion representations from verbal and nonverbal communication using only uncurated data. Compared to numerical labels or descriptions used in previous methods, communication naturally contains emotion information. Furthermore, acquiring emotion representations from communication is more congruent with the human learning process. We guide EmotionCLIP to attend to nonverbal emotion cues through subject-aware context encoding and verbal emotion cues using sentiment-guided contrastive learning. Extensive experiments validate the effectiveness and transferability of EmotionCLIP. Using merely linear-probe evaluation protocol, EmotionCLIP outperforms the state-of-the-art supervised visual emotion recognition methods and rivals many multimodal approaches across various benchmarks. We anticipate that the advent of EmotionCLIP will address the prevailing issue of data scarcity in emotion understanding, thereby fostering progress in related domains. The code and pre-trained models are available at https://github.com/Xeaver/EmotionCLIP.Comment: CVPR 202

Porosity Engineering of Dried Smart Poly(N-isopropylacrylamide) Hydrogels for Gas Sensing

A recent study unveiled the potential of acrylamide-based stimulus-responsive hydrogels for volatile organic compound detection in gaseous environments. However, for gas sensing, a large surface area, that is, a highly porous material, offering many adsorption sites is crucial. The large humidity variation in the gaseous environment constitutes a significant challenge for preserving an initially porous structure, as the pores tend to be unstable and irreversibly collapse. Therefore, the present investigation focuses on enhancing the porosity of smart PNiPAAm hydrogels under the conditions of a gaseous environment and the preservation of the structural integrity for long-term use. We have studied the influence of polyethylene glycol (PEG) as a porogen and the application of different drying methods and posttreatment. The investigations lead to the conclusion that only the combination of PEG addition, freeze-drying, and subsequent conditioning in high relative humidity enables a long-term stable formation of a porous surface and inner structure of the material. The significantly enhanced swelling response in a gaseous environment and in the test gas acetone is confirmed by gravimetric experiments of bulk samples and continuous measurements of thin films on piezoresistive pressure sensor chips. These measurements are furthermore complemented by an in-depth analysis of the morphology and microstructure. While the study was conducted for PNiPAAm, the insights and developed processes are general in nature and can be applied for porosity engineering of other smart hydrogel materials for VOC detection in gaseous environments

Stress‐Actuated Spiral Microelectrode for High‐Performance Lithium‐Ion Microbatteries

Miniaturization of batteries lags behind the success of modern electronic devices. Neither the device volume nor the energy density of microbatteries meets the requirement of microscale electronic devices. The main limitation for pushing the energy density of microbatteries arises from the low mass loading of active materials. However, merely pushing the mass loading through increased electrode thickness is accompanied by the long charge transfer pathway and inferior mechanical properties for long‐term operation. Here, a new spiral microelectrode upon stress‐actuation accomplishes high mass loading but short charge transfer pathways. At a small footprint area of around 1 mm2, a 21‐fold increase of the mass loading is achieved while featuring fast charge transfer at the nanoscale. The spiral microelectrode delivers a maximum area capacity of 1053 µAh cm−2 with a retention of 67% over 50 cycles. Moreover, the energy density of the cylinder microbattery using the spiral microelectrode as the anode reaches 12.6 mWh cm−3 at an ultrasmall volume of 3 mm3. In terms of the device volume and energy density, the cylinder microbattery outperforms most of the current microbattery technologies, and hence provides a new strategy to develop high‐performance microbatteries that can be integrated with miniaturized electronic devices

Alkaline Plasma-Activated Water (PAW) as an Innovative Therapeutic Avenue for Cancer Treatment

Plasma-activated water (PAW) is considered to be an effective anticancer agent due to the diverse aqueous reactive oxygen and nitrogen species (RONS: ROS and RNS), but the drawback of low dose and short duration of RONS in acidified PAW limits their clinical application. Herein, this Letter presents an innovative therapeutic avenue for cancer treatment with highly-effective alkaline PAW prepared by air surface plasma. This anticancer alkaline formulation is comprised of a rich mixture of highly chemical RONS and exhibited a prolonged half-life compared to acidified PAW. The H2O2, NO2-, and ONOO-/O2- concentrations in the alkaline PAW can reach up to 18-, 16-, and 14-fold higher than that in acidic PAW, and the half-life of these species was extended over 8-, 10-, and 26-fold, respectively. The synergistic potent redox action between these RONS with alkaline pH was shown to be more potent than acidic PAW for cancer cell inhibition in vitro. Furthermore, the alkaline PAW injection treatment also significantly inhibited tumor growth in tumor-bearing mice. The possible reasons are that the alkaline PAW would disturb the acid extracellular milieu leading to the inhibition of tumor growth and progression; moreover, the efficient and durable RONS with alkaline pH could induce significant cell apoptosis by altering cell biomolecules and participating apoptosis-related signaling pathways. These findings offer promising applications for developing a strategy with real potential for tumor treatment in clinical applications

Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

Mutations in the Cockayne Syndrome group B (CSB) gene cause cancer in mice, but premature aging and severe neurodevelopmental defects in humans. CSB, a member of the SWI/SNF family of chromatin remodelers, plays diverse roles in regulating gene expression and transcription-coupled nucleotide excision repair (TC-NER); however, these functions do not explain the distinct phenotypic differences observed between CSB-deficient mice and humans. During investigating Cockayne Syndrome-associated genome instability, we uncover an intrinsic mechanism that involves elongating RNA polymerase II (RNAPII) undergoing transient pauses at internal T-runs where CSB is required to propel RNAPII forward. Consequently, CSB deficiency retards RNAPII elongation in these regions, and when coupled with G-rich sequences upstream, exacerbates genome instability by promoting R-loop formation. These R-loop prone motifs are notably abundant in relatively long genes related to neuronal functions in the human genome, but less prevalent in the mouse genome. These findings provide mechanistic insights into differential impacts of CSB deficiency on mice versus humans and suggest that the manifestation of the Cockayne Syndrome phenotype in humans results from the progressive evolution of mammalian genomes

Market Stakeholder Analysis of the Practical Implementation of Carbonation Curing on Steel Slag for Urban Sustainable Governance

Carbonation curing on steel slag is one of the most promising technologies for the iron and steel industry to manage its solid waste and carbon emissions. However, the technology is still in its demonstration stage. This paper investigates the market stakeholders of carbonation curing on steel slag for construction materials for its effective application by taking China as a case study. A holistic analysis of the competition, market size, and stakeholders of carbonation curing on steel slag was carried out through a literature review, a survey, a questionnaire, and interviews. The results showed that carbonation curing on steel slag had the advantages of high quality, high efficiency, low cost, and carbon reduction compared with other technologies. Shandong province was the most suitable province for the large-scale primary application of the technology. Stakeholder involvement to establish information platforms, enhance economic incentives, and promote adequate R&D activities would promote carbonation curing of steel slag into practice. This paper provides a reference for the commercialization of carbonation curing on similar calcium- and magnesium-based solid waste materials

Identification and on-site application of the main hazard-causing stratum of overlying strata in coal mines

In response to the challenging task of accurately identifying the main hazard-causing layer of overlying strata in the coal mine surface hydraulic fracturing construction, this study focuses on the industrial test of ground hydraulic fracturing at the 401102 working face of the Mengcun Coal Mine. The research is conducted using the methods of theoretical analysis, microseismic monitoring, and on-site investigation to reveal the dynamic disaster mechanism of mine earthquakes and rock bursts induced by the movement of thick and hard overlying strata in the coal mines. The relationship between the movement characteristics of thick and hard overlying strata based on a three-zone structure loading model of overlying strata and induced dynamic disasters is analyzed, and a prediction model for mining seismic energy and an estimation model for equivalent additional stress in mining areas based on the movement state of key layers are established. A coal mine identification technology for the main hazard-causing layer of overlying strata is proposed based on the K-means clustering algorithm and the elbow rule. The construction layer for hydraulic fracturing is determined, and an industrial test is carried out on-site. The effectiveness is verified based on the microseismic monitoring data and theoretical analysis results, leading to the following conclusions. In the Mengcun Coal Mine’s 401102 working face, both the key stratum responsible for rock bursts and mine seismic activities can be traced to the R9 key stratum of the Anding Group, situated 66 meters away from the coal seam. The primary fracturing movement of this critical stratum R9 imparts an equivalent supplementary disturbance stress value of 7.23 MPa, with the seismic energy liberated by this initial rupture motion quantifying to 6.08×105 J, thereby indicating a pronounced susceptibility towards catastrophic occurrences. After fracturing the key layer which induces mining earthquakes and rock bursts, the theoretical value of the mine earthquake energy is reduced by 94%, and the theoretical value of the equivalent disturbance stress of the working face is reduced by 76%. High-energy microseismic events above the working face with an energy of 5×103 J show a noticeable upward trend, with an upward movement of approximately 15 m. The frequency ratio of microseismic events with an energy level of 103 J or higher significantly decreases from 60.39% to 17.89%, and the maximum microseismic event energy decreases from 6.65×105 J to 9.75×103 J. The proportion of microseismic events with an energy level of 102 J and below significantly increases from 39.61% to 82.11%