4,406 research outputs found

    Experimental Analysis of an Automotive Air Conditioning System With Two-Phase Flow Measurements

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    Environmental influences on the intensity changes of tropical cyclones over the western North Pacific

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    The influence of environmental conditions on the intensity changes of tropical cyclones (TCs) over the western North Pacific (WNP) is investigated through examination of 37 TCs during 2000–2011 that interacted directly with the western North Pacific subtropical high (WNPSH). Comprehensive composite analysis of the environmental conditions is performed for two stages of storms: one is categorized as intensifying events (maximum wind speed increases by 15 kn over 48 h) and the other is categorized as weakening events (maximum wind speed decreases by 15 kn over 48 h). Comparison of the composite analysis of these two cases show that environmental conditions associated with the WNPSH play important roles in the intensity changes of TCs over the WNP. When a TC moves along the southern periphery of the WNPSH, the relatively weaker easterly environmental vertical wind shear helps bring warm moist air from the south and southeast to its southeast quadrant within 500 km, which is favorable for the TC to intensify. However, when a TC moves along the western edge of the WNPSH, under the combined influences of the WNPSH and an upper-level westerly trough, a strong westerly vertical shear promotes the intrusion of dry environmental air associated with the WNPSH from the north and northwest, which may lead to the inhibition of moisture supply and convection over the western half of the TC and thus its weakening. These composite results are consistent with those with additional geographic restrictions, suggesting that the dry air intrusion and the vertical wind shear (VWS) associated with the WNPSH, indeed affect the intensity changes of TCs over the WNP beyond the difference related solely to variations in geographical locations. The average sea surface temperature (SST) of 27.6 °C for the weakening events is also lower than an average of 28.9 °C for the strengthening events, but remains above the critical value of 27 °C for TC intensification, suggesting that the SST may be regarded as a less positive factor for the weakening events

    Mechanical Character of Typica1 Plant Leaf Surfaces

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    The hardness of typical plant leaves surfaces was investigated and analyzed by nano-hardness tester. Results show that the mechanical character of varied texture and varied surface morphologies shows regularity. The hardness of coriaceous fresh leaves (Bambusa phyllostachys pubescens etc.) and ligneous leaves is great. Waxiness leaves′ hardness (such as Nelumbo nucifera Gaertn, Canna indica Linn (generalis) is little. The hardness of convex morphology part is better than that of concave morphology part on non-smooth morphology leaf surfaces. And that the hardness of surface layer is better than that of internal layer in the same leaf. This study may be important biological foundation for design and fabrication of bionic engineering surface and composite materials. Key words: engineering bionic; plant leaf; hardness; mechanical characte

    Potential biomarkers relating pathological proteins, neuroinflammatory factors and free radicals in PD patients with cognitive impairment: a cross-sectional study

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    BACKGROUND: Cognitive impairment strikingly reduces the quality of life of Parkinson’s disease (PD) patients. Studies find that pathological proteins, neuroinflammatory factors and free radicals may involve in the pathogenesis of cognitive impairment of PD, however, results are inconclusive. METHODS: We recruited 62 PD patients and 31 healthy controls. PD patients were identified with cognitive impairment, including PD with mild cognitive impairment (PD-MCI) and PD with dementia (PDD) according to the diagnostic criteria for PD-MCI and PDD issued by Movement Disorder Society Task Force. The levels of pathological proteins, including β-amyloid 1–42 (Aβ1-42),Total-tau (T-tau) and phosphorelated tau (P-tau), neuroinflammatory factors,including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), interferon-γ (INF-γ) and prostaglandin E(2) (PGE(2)), free radicals, including hydroxyl radical (·OH), hydrogen peroxide (H(2)O(2)) and nitric oxide (NO) in cerebrospinal fluid(CSF) were detected. The levels of above factors in CSF were compared among healthy controls and patients with and without cognitive impairment. Correlation analyses were performed between Montreal Cognitive Assessment (MoCA) score and the levels of above factors in CSF. RESULTS: T-tau level in CSF from PD-CI patients are significantly elevated comparing with those without cognitive impairment and controls (P = 0.016 and 0.004, respectively). The levels of P-tau (S396) and · OH in PD-CI patients are significantly higher than controls (P = 0.001 and 0.014, respectively). IL-6 levels in PD-CI patients are strikingly enhanced comparing with those without cognitive impairment (P = 0.005). MoCA score is negatively correlated with the levels of T-tau (r = -0.340), P-tau (S396) (r = -0.448), IL-6 (r = -0.489) and · OH (r = -0.504) in PD-CI patients. CONCLUSIONS: Elevated levels of T-tau, P-tau (S396), IL-6 and · OH in CSF are significantly correlated with cognitive impairment in PD patients. This investigation may suggest the potential biomarkers relating pathological proteins, neuroinflammatory factors and free radicals in PD patients with cognitive impairment
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