131 research outputs found
Face Anti-Spoofing by Learning Polarization Cues in a Real-World Scenario
Face anti-spoofing is the key to preventing security breaches in biometric
recognition applications. Existing software-based and hardware-based face
liveness detection methods are effective in constrained environments or
designated datasets only. Deep learning method using RGB and infrared images
demands a large amount of training data for new attacks. In this paper, we
present a face anti-spoofing method in a real-world scenario by automatic
learning the physical characteristics in polarization images of a real face
compared to a deceptive attack. A computational framework is developed to
extract and classify the unique face features using convolutional neural
networks and SVM together. Our real-time polarized face anti-spoofing (PAAS)
detection method uses a on-chip integrated polarization imaging sensor with
optimized processing algorithms. Extensive experiments demonstrate the
advantages of the PAAS technique to counter diverse face spoofing attacks
(print, replay, mask) in uncontrolled indoor and outdoor conditions by learning
polarized face images of 33 people. A four-directional polarized face image
dataset is released to inspire future applications within biometric
anti-spoofing field.Comment: 14pages,8figure
Effects of SOCS3 on the development of colon cancer via regulation of HIF-1α
Purpose: To investigate the influence of suppressor of cytokine signaling 3 (SOCS3) on rats with colon cancer (CC).
Methods: Sprague-Dawley (SD) rats were randomly divided into CC group and control group, and then CC rat model was constructed. The expression of SOCS3 in CC tissues was determined by quantitative real time-polymerase chain reaction (qRT-PCR). Hematoxylin-eosin staining (H&E) was used to examine colon tissue morphology. Immunohistochemistry (IHC) staining assay was performed to determine the expression of SOCS3 protein in colon tissues. The contents of HIF-1α, phosphorylated phosphatidylinositol 3-hydroxy kinase (p-PI3K), and phosphorylated protein kinase B (p-AKT) proteins were determined by Western blotting (WB).
Results: Compared with that in the control group, the number of tumors in CC group was significantly increased (p < 0.05). 2). On the other hand, protein and message ribonucleic acid (mRNA) expressions of SOCS3 were down-regulated in CC group (p < 0.05). 3), while protein expressions of p-PI3K, p-AKT and HIF-1α were raised in CC group (p < 0.05).
Conclusion: SOCS3 is lowly expressed in CC rats, and promotes the expression of HIF-1α by activating PI3K/AKT signaling pathway. Thus, SOCS3 provides a therapeutic strategy for the management of colon cancer.
Keywords: Colon cancer; Suppressor of cytokine signaling protein 3 (SOCS3); Hypoxia inducible factor-1
Effects of suppressor of cytokine signaling 3 (SOCS3) on the development of colon cancer via regulation of HIF-1α
Purpose: To investigate the influence of suppressor of cytokine signaling 3 (SOCS3) on rats with colon cancer (CC).
Methods: Sprague-Dawley (SD) rats were randomly divided into CC group and control group. CC models were constructed. The expression of SOCS3 in CC tissues was determined by quantitative real time-polymerase chain reaction (qRT-PCR). Hematoxylin-eosin staining (H&E) was used to examine colon tissue morphology, while immunohistochemistry (IHC) staining assay was performed to determine the expression of SOCS3 protein in colon tissues. The content of HIF-1α, phosphorylated phosphatidylinositol 3-hydroxy kinase (p-PI3K), and phosphorylated protein kinase B (p-AKT) proteins was determined by Western blotting (WB).
Results: Compared with that in the control group, the number of tumors in the CC group was significantly increased (p < 0.05). Protein and messenger ribonucleic acid (mRNA) expressions of SOCS3 were down-regulated in CC group (p < 0.05), while protein expressions of p-PI3K, p-AKT and HIF-1α were significantly elevated in CC group (p < 0.05).
Conclusion: SOCS3 is poorly expressed in CC rats, and promotes the expression of HIF-1α by activating PI3K/AKT signaling pathway. The findings, thus, provide a probable strategy for management of colon cancer
Construction and characterization of a bacterial artificial chromosome library for Gossypium mustelinum
A bacterial artificial chromosome (BAC) library for G. mustelinum Miers ex G. Watt (AD4)
was constructed. Intact nuclei from G. mustelinum (AD4) were used to isolate high molecular
weight DNA, which was partially cleaved with Hind III and cloned into pSMART BAC (Hind
III) vectors. The BAC library consisted of 208,182 clones arrayed in 542 384-microtiter
plates, with an average insert size of 121.72 kb ranging from 100 to 150 kb. About 2% of the
clones did not contain inserts. Based on an estimated genome size of 2372 Mb for G. mustelinum, the BAC library was estimated to have a total coverage of 10.50 × genome equivalents. The high capacity library of G. mustelinum will serve as a giant gene resource for
map-based cloning of quantitative trait loci or genes associated with important agronomic
traits or resistance to Verticillium wilt, physical mapping and comparative genome analysis
Comparison of Quality and Antioxidant Activity of Fu Brick Tea in Different Regions, and Its "Golden Flower" Fungi Morphological Characteristics
The chemical composition, quality characteristics, antioxidant activity, and "golden flower" fungi morphology of Fu brick tea from Hunan, Hubei, Shaanxi, Guizhou, and Zhejiang provinces of China had been researched in this study. The results revealed significant differences in the contents of chemical components in different Fu brick tea (P<0.05). Among them, Fu brick tea from Guizhou had the highest contents of free amino acids and total catechins (9.03, 63.12 mg/g, respectively), while Zhejiang Fu brick tea standed out with the most elevated content of tea polyphenols and flavonoids (132.93, 8.63 mg/g, respectively). According to the electronic taste evaluation, the Fu brick tea from Hunan and Shaanxi exhibited the strongest bitterness and astringency, respectively. Meanwhile,the Zhejiang sample had the most powerful aftertaste bitterness and saltiness, whereas the Guizhou sample demonstrated the strongest umami and richness. Different Fu brick teas had different antioxidant activities, with samples from Hubei and Zhejiang showing higher levels of antioxidant activity. Correlation analysis revealed a significant positive correlation between the main chemical components and taste attributes, and tea polyphenols contributed to the antioxidant activity of Fu brick tea. Additionally, morphology indicated that the five strains of "golden flower" fungi from different origins showed slight differences in the same medium, while the Hunan strain grew faster than the others. This study taked an important role in comprehending the chemical quality of Fu brick tea from different origins
- …