44,914 research outputs found
Towards Faithful Neural Table-to-Text Generation with Content-Matching Constraints
Text generation from a knowledge base aims to translate knowledge triples to
natural language descriptions. Most existing methods ignore the faithfulness
between a generated text description and the original table, leading to
generated information that goes beyond the content of the table. In this paper,
for the first time, we propose a novel Transformer-based generation framework
to achieve the goal. The core techniques in our method to enforce faithfulness
include a new table-text optimal-transport matching loss and a table-text
embedding similarity loss based on the Transformer model. Furthermore, to
evaluate faithfulness, we propose a new automatic metric specialized to the
table-to-text generation problem. We also provide detailed analysis on each
component of our model in our experiments. Automatic and human evaluations show
that our framework can significantly outperform state-of-the-art by a large
margin.Comment: Accepted at ACL202
Design and Implementation of a FPGA and DSP Based MIMO Radar Imaging System
The work presented in this paper is aimed at the implementation of a real-time multiple-input multiple-output (MIMO) imaging radar used for area surveillance. In this radar, the equivalent virtual array method and time-division technique are applied to make 16 virtual elements synthesized from the MIMO antenna array. The chirp signal generater is based on a combination of direct digital synthesizer (DDS) and phase locked loop (PLL). A signal conditioning circuit is used to deal with the coupling effect within the array. The signal processing platform is based on an efficient field programmable gates array (FPGA) and digital signal processor (DSP) pipeline where a robust beamforming imaging algorithm is running on. The radar system was evaluated through a real field experiment. Imaging capability and real-time performance shown in the results demonstrate the practical feasibility of the implementation
N-Phenylcyclohexanecarboxamide
In the title compound, C13H17NO, the cyclohexane ring adopts a chair conformation and the amide C(=O)—N moiety is almost coplanar with the phenyl ring [C—N—C—O = 4.1 (2)°]. In the crystal, molecules are linked to form a C(4) infinite [001] chain via N—H⋯O hydrogen bonds, unlike the cyclic motif seen in related structures
XL-NBT: A Cross-lingual Neural Belief Tracking Framework
Task-oriented dialog systems are becoming pervasive, and many companies
heavily rely on them to complement human agents for customer service in call
centers. With globalization, the need for providing cross-lingual customer
support becomes more urgent than ever. However, cross-lingual support poses
great challenges---it requires a large amount of additional annotated data from
native speakers. In order to bypass the expensive human annotation and achieve
the first step towards the ultimate goal of building a universal dialog system,
we set out to build a cross-lingual state tracking framework. Specifically, we
assume that there exists a source language with dialog belief tracking
annotations while the target languages have no annotated dialog data of any
form. Then, we pre-train a state tracker for the source language as a teacher,
which is able to exploit easy-to-access parallel data. We then distill and
transfer its own knowledge to the student state tracker in target languages. We
specifically discuss two types of common parallel resources: bilingual corpus
and bilingual dictionary, and design different transfer learning strategies
accordingly. Experimentally, we successfully use English state tracker as the
teacher to transfer its knowledge to both Italian and German trackers and
achieve promising results.Comment: 13 pages, 5 figures, 3 tables, accepted to EMNLP 2018 conferenc
Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer.
Summary: CDK4/6 inhibitors are effective against cancer cells expressing the tumor suppressor RB1, but not RB1-deficient cells, posing the challenge of how to target RB1 loss. In triple-negative breast cancer (TNBC), RB1 and PTEN are frequently inactivated together with TP53. We performed kinome/phosphatase inhibitor screens on primary mouse Rb/p53-, Pten/p53-, and human RB1/PTEN/TP53-deficient TNBC cell lines and identified CDC25 phosphatase as a common target. Pharmacological or genetic inhibition of CDC25 suppressed growth of RB1-deficient TNBC cells that are resistant to combined CDK4/6 plus CDK2 inhibition. Minimal cooperation was observed in vitro between CDC25 antagonists and CDK1, CDK2, or CDK4/6 inhibitors, but strong synergy with WEE1 inhibition was apparent. In accordance with increased PI3K signaling following long-term CDC25 inhibition, CDC25 and PI3K inhibitors effectively synergized to suppress TNBC growth both in vitro and in xenotransplantation models. These results provide a rationale for the development of CDC25-based therapies for diverse RB1/PTEN/TP53-deficient and -proficient TNBCs. : Liu et al. report that inhibition of the protein phosphatase CDC25 kills diverse triple-negative breast cancer (TNBC) cells. Moreover, CDC25 antagonists cooperate with other drugs, such as PI3K inhibitors, to efficiently suppress growth of human TNBC engrafted into mice. Keywords: triple negative breast cancer, basal-like breast cancer, therapy, RB1, PTEN, TP53, CDC25, WEE1, CHK1, checkpoint contro
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