7 research outputs found
Exploring Browsing Behavior of Product Information in an M-commerce Application: a Transaction Log Analysis
This research aims to describe the information browsing and merchandise purchasing behaviors of the users in an M-commerce application. Data used in this research comes from the transaction logs of 290 heavy users in March 2015. We established the mapping between the request parameters in the log and the user information behavior to future analyze the pattern of user behavior. People are most concerned about the details of items, and actively share their favorite items and shops to others. The times of view is power-law distribution. We also find that the items which are viewed 9 times and are included in the submitted order are most likely to be bought. There is a positive correlation between the purchase of items and the numbers of browsing and sharing behaviors
Sources and Eco-toxicological Effects of Ultrafine Particle Matters
Environmental air pollution has become an important threat to human health. As one of the major air pollutants, atmospheric particulates have received attention widely. In which, ultrafine particulate matters (UPM) with diameter below 0.1μm have become the main components of ambient air particulates, posing a serious threat to the health of the organism. Therefore, this paper investigated and summarized the research on ultrafine particles at home and abroad, systematically analysed the sources of UPM in ambient air, investigated its toxicological effects of ultrafine particles on the respiratory system, cardiovascular system, and central nervous system of organisms. This study will provide a theoretical reference for environmental air protection and pollution control in China
IL‐1/IL‐1R signaling induced by all‐ trans ‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium
Soluble CD24 is an inflammatory biomarker in early and seronegative rheumatoid arthritis
AbstractIntroduction: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterized by autoantibody production, joint inflammation and bone destruction. Nearly 1/3 of RA patients with the active disease also exhibit a normal range of ESR and CRP. Here we assessed the performance and clinical significance of soluble CD24 (sCD24) as a biomarker of disease activity in RA.Methods: A total of 269 RA patients, 59 primary Sjogren’s syndrome (SS) patients, 81 systematic lupus erythematosus (SLE) patients, 76 osteoarthritis (OA) patients and 97 healthy individuals (HC) were included in this study. Soluble CD24 in sera were detected by ELISA. Therefore, the concentration of sCD24 was analyzed in RA patients with different disease activity statuses.Results: The sCD24 was significantly increased in RA (2970 pg/mL), compared to other rheumatic diseases (380-520 pg/mL) and healthy individuals (320 pg/mL). Moreover, sCD24 was elevated in 66.67% of early RA and 61.11% of seronegative RA patients. In addition, sCD24 was significantly correlated with the disease duration and inflammatory indicators.Conclusion: The sCD24 could be an inflammatory biomarker in RA patients, especially in early and seronegative patients
Soluble CD24 is an inflammatory biomarker in early and seronegative rheumatoid arthritis
Introduction: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterized by autoantibody production, joint inflammation and bone destruction. Nearly 1/3 of RA patients with the active disease also exhibit a normal range of ESR and CRP. Here we assessed the performance and clinical significance of soluble CD24 (sCD24) as a biomarker of disease activity in RA. Methods: A total of 269 RA patients, 59 primary Sjogren’s syndrome (SS) patients, 81 systematic lupus erythematosus (SLE) patients, 76 osteoarthritis (OA) patients and 97 healthy individuals (HC) were included in this study. Soluble CD24 in sera were detected by ELISA. Therefore, the concentration of sCD24 was analyzed in RA patients with different disease activity statuses. Results: The sCD24 was significantly increased in RA (2970 pg/mL), compared to other rheumatic diseases (380-520 pg/mL) and healthy individuals (320 pg/mL). Moreover, sCD24 was elevated in 66.67% of early RA and 61.11% of seronegative RA patients. In addition, sCD24 was significantly correlated with the disease duration and inflammatory indicators. Conclusion: The sCD24 could be an inflammatory biomarker in RA patients, especially in early and seronegative patients.</p