2,091 research outputs found

    Progress in Californium-252 Neutron Brachytherapy

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    Influence of an aperture on the performance of a two-degree-of-freedom iron-cored spherical permanent-magnet actuator

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    Abstract—This paper describes a computational and experimental study of a two-degree-of-freedom spherical permanent-magnet actuator equipped with an iron stator. In particular, it considers the effect of introducing an aperture in the stator core to facilitate access to the armature. The resultant magnetic field distribution in the region occupied by the stator windings, the net unbalanced radial force, and the resulting reluctance torque are determined by three-dimensional magnetostatic finite-element analysis. The predicted reluctance torque is validated experimentally, and its implications on actuator performance are described

    Clinician-targeted interventions to reduce antibiotic prescribing for acute respiratory infections in primary care:An overview of systematic reviews

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    This is the protocol for a review and there is no abstract. The objectives are as follows: To systematically review the literature and appraise the existing evidence from systematic reviews regarding the effects of interventions, aimed at changing clinician behaviour, to reduce antibiotic prescribing for ARIs in primary care

    Sex differences in white matter development during adolescence: A DTI study

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    Adolescence is a complex transitional period in human development, composing physical maturation, cognitive and social behavioral changes. The objective of this study is to investigate sex differences in white matter development and the associations between intelligence and white matter microstructure in the adolescent brain using diffusion tensor imaging (DTI) and tract-based spatial statistics (TBSS). In a cohort of 16 typically-developing adolescents aged 13 to 17 years, longitudinal DTI data were recorded from each subject at two time points that were one year apart. We used TBSS to analyze the diffusion indices including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD). Our results suggest that boys (13–18 years) continued to demonstrate white matter maturation, whereas girls appeared to reach mature levels earlier. In addition, we identified significant positive correlations between FA and full-scale intelligence quotient (IQ) in the right inferior fronto-occipital fasciculus when both sexes were looked at together. Only girls showed significant positive correlations between FA and verbal IQ in the left cortico-spinal tract and superior longitudinal fasciculus. The preliminary evidence presented in this study supports that boys and girls have different developmental trajectories in white matter microstructure

    Star Formation and Gas Kinematics of Quasar Host Galaxies at z~6: New insights from ALMA

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    We present ALMA observations of the [C II] 158 micron fine structure line and dust continuum emission from the host galaxies of five redshift 6 quasars. We also report complementary observations of 250 GHz dust continuum and CO (6-5) line emission from the z=6.00 quasar SDSS J231038.88+185519.7. The ALMA observations were carried out in the extended array at 0.7" resolution. We have detected the line and dust continuum in all five objects. The derived [C II] line luminosities are 1.6x10^{9} to 8.8x10^{9} Lsun and the [C II]-to-FIR luminosity ratios are 3.0-5.6x10^{-4}, which is comparable to the values found in other high-redshift quasar-starburst systems and local ultra-luminous infrared galaxies. The sources are marginally resolved and the intrinsic source sizes (major axis FWHM) are constrained to be 0.3" to 0.6" (i.e., 1.7 to 3.5 kpc) for the [C II] line emission and 0.2" to 0.4" (i.e., 1.2 to 2.3 kpc) for the continuum. These measurements indicate that there is vigorous star formation over the central few kpc in the quasar host galaxies. The ALMA observations also constrain the dynamical properties of the atomic gas in the starburst nuclei. The intensity-weighted velocity maps of three sources show clear velocity gradients. Such velocity gradients are consistent with a rotating, gravitationally bound gas component, although they are not uniquely interpreted as such. Under the simplifying assumption of rotation, the implied dynamical masses within the [C II]-emitting regions are of order 10^{10} to 10^{11} Msun. Given these estimates, the mass ratios between the SMBHs and the spheroidal bulge are an order of magnitude higher than the mean value found in local spheroidal galaxies, which is in agreement with results from previous CO observations of high redshift quasars.Comment: 25 pages, 5 figures, accepted for publication in Ap

    The Apparent Host Galaxy of PKS 1413+135: HST, ASCA and VLBA Observations

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    PKS 1413+135 (z=0.24671) is one of very few radio-loud AGN with an apparent spiral host galaxy. Previous authors have attributed its nearly exponential infrared cutoff to heavy absorption but have been unable to place tight limits on the absorber or its location in the optical galaxy. In addition, doubts remain about the relationship of the AGN to the optical galaxy given the observed lack of re-emitted radiation. We present new HST, ASCA and VLBA observations which throw significant new light on these issues. The HST observations reveal an extrremely red color (V-H = 6.9 mag) for the active nucleus of PKS 1413+135, requiring both a spectral turnover at a few microns due to synchrotron aging and a GMC-sized absorber. We derive an intrinsic column N_H = 4.6^{+2.1}_{-1.6} times 10^{22}cm^{-2} and covering fraction f = 0.12^{+0.07}_{-0.05}. As the GMC is likely in the disk of the optical galaxy, our sightline is rather unlikely (P ~ 2 times 10^{-4}). The properties of the GMC typical of GMCs in our own galaxy. The HI absorber appears centered 25 milliarcseconds away from the nucleus, while the X-ray and nearly all of the molecular absorbers must cover the nucleus, implying a complicated geometry and cloud structure, with a molecular core along our line of sight to the nucleus. Interestingly, the HST/NICMOS data require the AGN to be decentered relative to the optical galaxy by 13 +/- 4 milliarcseconds. This could be interpreted as suggestive of an AGN location far in the background compared to the optical galaxy, but it can also be explained by obscuration and/or nuclear structure, which is more consistent with the observed lack of multiple images.Comment: 27 pages, 8 figures; accepted to A

    Self-assembly of Microcapsules via Colloidal Bond Hybridization and Anisotropy

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    Particles with directional interactions are promising building blocks for new functional materials and may serve as models for biological structures. Mutually attractive nanoparticles that are deformable due to flexible surface groups, for example, may spontaneously order themselves into strings, sheets and large vesicles. Furthermore, anisotropic colloids with attractive patches can self-assemble into open lattices and colloidal equivalents of molecules and micelles. However, model systems that combine mutual attraction, anisotropy, and deformability have---to the best of our knowledge---not been realized. Here, we synthesize colloidal particles that combine these three characteristics and obtain self-assembled microcapsules. We propose that mutual attraction and deformability induce directional interactions via colloidal bond hybridization. Our particles contain both mutually attractive and repulsive surface groups that are flexible. Analogous to the simplest chemical bond, where two isotropic orbitals hybridize into the molecular orbital of H2, these flexible groups redistribute upon binding. Via colloidal bond hybridization, isotropic spheres self-assemble into planar monolayers, while anisotropic snowman-like particles self-assemble into hollow monolayer microcapsules. A modest change of the building blocks thus results in a significant leap in the complexity of the self-assembled structures. In other words, these relatively simple building blocks self-assemble into dramatically more complex structures than similar particles that are isotropic or non-deformable

    New Frontiers for Terrestrial-sized to Neptune-sized Exoplanets In the Era of Extremely Large Telescopes

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    Surveys reveal that terrestrial- to Neptune-sized planets (1 <R<< R < 4 REarth_{\rm{Earth}}) are the most common type of planets in our galaxy. Detecting and characterizing such small planets around nearby stars holds the key to understanding the diversity of exoplanets and will ultimately address the ubiquitousness of life in the universe. The following fundamental questions will drive research in the next decade and beyond: (1) how common are terrestrial to Neptune-sized planets within a few AU of their host star, as a function of stellar mass? (2) How does planet composition depend on planet mass, orbital radius, and host star properties? (3) What are the energy budgets, atmospheric dynamics, and climates of the nearest worlds? Addressing these questions requires: a) diffraction-limited spatial resolution; b) stability and achievable contrast delivered by adaptive optics; and c) the light-gathering power of extremely large telescopes (ELTs), as well as multi-wavelength observations and all-sky coverage enabled by a comprehensive US ELT Program. Here we provide an overview of the challenge, and promise of success, in detecting and comprehensively characterizing small worlds around the very nearest stars to the Sun with ELTs. This white paper extends and complements the material presented in the findings and recommendations published in the National Academy reports on Exoplanet Science Strategy and Astrobiology Strategy for the Search for Life in the Universe.Comment: Astro2020 Science White Pape
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