395 research outputs found
On the spectrum of operators concerned with the reduced singular Cauchy integral
We investigate spectrums of the reduced singular Cauchy operator and its real and imaginary components
Structure-Aware Generation Network for Recipe Generation from Images
Sharing food has become very popular with the development of social media.
For many real-world applications, people are keen to know the underlying
recipes of a food item. In this paper, we are interested in automatically
generating cooking instructions for food. We investigate an open research task
of generating cooking instructions based on only food images and ingredients,
which is similar to the image captioning task. However, compared with image
captioning datasets, the target recipes are long-length paragraphs and do not
have annotations on structure information. To address the above limitations, we
propose a novel framework of Structure-aware Generation Network (SGN) to tackle
the food recipe generation task. Our approach brings together several novel
ideas in a systematic framework: (1) exploiting an unsupervised learning
approach to obtain the sentence-level tree structure labels before training;
(2) generating trees of target recipes from images with the supervision of tree
structure labels learned from (1); and (3) integrating the inferred tree
structures with the recipe generation procedure. Our proposed model can produce
high-quality and coherent recipes, and achieve the state-of-the-art performance
on the benchmark Recipe1M dataset.Comment: Published at ECCV 202
Learning Structural Representations for Recipe Generation and Food Retrieval
Food is significant to human daily life. In this paper, we are interested in
learning structural representations for lengthy recipes, that can benefit the
recipe generation and food cross-modal retrieval tasks. Different from the
common vision-language data, here the food images contain mixed ingredients and
target recipes are lengthy paragraphs, where we do not have annotations on
structure information. To address the above limitations, we propose a novel
method to unsupervisedly learn the sentence-level tree structures for the
cooking recipes. Our approach brings together several novel ideas in a
systematic framework: (1) exploiting an unsupervised learning approach to
obtain the sentence-level tree structure labels before training; (2) generating
trees of target recipes from images with the supervision of tree structure
labels learned from (1); and (3) integrating the learned tree structures into
the recipe generation and food cross-modal retrieval procedure. Our proposed
model can produce good-quality sentence-level tree structures and coherent
recipes. We achieve the state-of-the-art recipe generation and food cross-modal
retrieval performance on the benchmark Recipe1M dataset.Comment: Accepted at IEEE Transactions on Pattern Analysis and Machine
Intelligence. arXiv admin note: substantial text overlap with
arXiv:2009.0094
Sca-1+ Cardiac Stem Cells Mediate Acute Cardioprotection via Paracrine Factor SDF-1 following Myocardial Ischemia/Reperfusion
Cardiac stem cells (CSCs) promote myocardial recovery following ischemia through their regenerative properties. However, little is known regarding the implication of paracrine action by CSCs in the setting of myocardial ischemia/reperfusion (I/R) injury although it is well documented that non-cardiac stem cells mediate cardioprotection via the production of paracrine protective factors. Here, we studied whether CSCs could initiate acute protection following global myocardial I/R via paracrine effect and what component from CSCs is critical to this protection.A murine model of global myocardial I/R was utilized to investigate paracrine effect of Sca-1+ CSCs on cardiac function. Intracoronary delivery of CSCs or CSC conditioned medium (CSC CM) prior to ischemia significantly improved myocardial function following I/R. siRNA targeting of VEGF in CSCs did not affect CSC-preserved myocardial function in response to I/R injury. However, differentiation of CSCs to cardiomyocytes (DCSCs) abolished this protection. Through direct comparison of the protein expression profiles of CSCs and DCSCs, SDF-1 was identified as one of the dominant paracrine factors secreted by CSCs. Blockade of the SDF-1 receptor by AMD3100 or downregulated SDF-1 expression in CSCs by specific SDF-1 siRNA dramatically impaired CSC-induced improvement in cardiac function and increased myocardial damage following I/R. Of note, CSC treatment increased myocardial STAT3 activation after I/R, whereas downregulation of SDF-1 action by blockade of the SDF-1 receptor or SDF-1 siRNA transfection abolished CSC-induced STAT3 activation. In addition, inhibition of STAT3 activation attenuated CSC-mediated cardioprotection following I/R. Finally, post-ischemic infusion of CSC CM was shown to significantly protect I/R-caused myocardial dysfunction.This study suggests that CSCs acutely improve post-ischemic myocardial function through paracrine factor SDF-1 and up-regulated myocardial STAT3 activation
Online multimodal distance metric learning with application to image retrieval
Ministry of Education, Singapore under its Academic Research Funding Tier
Control scheme for LTI systems with Lipschitz non‐linearity and unknown time‐varying input delay
A human monoclonal antibody blocking SARS-CoV-2 infection
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19
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