Algebraic Cayley Graphs over Finite Fields

A new algebraic Cayley graph is constructed using finite fields. Its connectedness and diameter bound are studied via Weil's estimate for character sums. These graphs provide a new source of expander graphs, extending classical results of Chung

Diagnosis of the Coenosia pedella-group (Diptera: Muscidae), with descriptions of three new species from China

The Coenosia pedella-group is established and defined by the combination of the following characters: most species have one presutural dorsocentral seta, costa reaching the tip of media vein, abdomen with distinct spots, hind tibia with dorsal setae, lower calypter at least subequal in length to upper calypter, basis of cerci and surstyli of male short, length of cerci at most four times as long as its width, most of cerci enlarged in distal 1/3 and surstyli subtriangular with width of basal part longer than 1/3 of length. Three new species are described: C. disclambosa Xue & Wang sp. n., C. maoershanensis Xue & Wang sp. n. and C. sublacteipennis Xue&Wang sp. n. A key to the males of Palaearctic Region species of the Coenosia pedella-group is given

Searching for Charged Higgs Boson in Polarized Top Quark

The charged Higgs boson is quite common in many new physics models. In this study we examine the potential of observing a heavy charged Higgs boson in its decay mode of top-quark and bottom-quark in the Type-II Two-Higgs-Doublet-Model. In this model, the chirality structure of the coupling of charged Higgs boson to the top- and bottom-quark is very sensitive to the value of $\tan\beta$. As the polarization of the top-quark can be measured experimentally from the top-quark decay products, one could make use of the top-quark polarization to determine the value of $\tan\beta$. We preform a detailed analysis of measuring top-quark polarization in the production channels $gb\to tH^-$ and $g\bar{b}\to \bar{t}H^+$. We calculate the helicity amplitudes of the charged Higgs boson production and decay.Our calculation shows that the top-quark from the charged Higgs boson decay provides a good probe for measuring $\tan\beta$, especially for the intermediate $\tan\beta$ region. On the contrary, the top-quark produced in association with the charged Higgs boson cannot be used to measure $\tan\beta$ because its polarization is highly contaminated by the $t$-channel kinematics.Comment: 21 pages, 12 figures, 2 table

Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds.

Previously, we only apply a traditional Chinese medicine (TCM) Danshen-Chuanxiong-Honghua (DCH) for cardioprotection via anti-inflammation in rats of acute myocardial infarction by occluding coronary artery. Presently, we select not only DCH but also its main absorbed compound ferulic acid (FA) for cerebra protection via similar action of mechanism above in animals of the transient middle cerebral artery occlusion (tMCAO). We investigated whether oral administration of DCH and FA could ameliorate MCAO-induced brain lesions in animals. By using liquid chromatography-tandem mass spectrometry (LC-MS/MS), we analyzed four compounds, including tanshinol, salvianolic acid B, hydroxysafflor yellow A and especially FA as the putative active components of DCH extract in the plasma, cerebrospinal fluid and injured hippocampus of rats with MCAO. In our study, it was assumed that FA played a similar neuroprotective role to DCH. We found that oral pretreatment with DCH (10 or 20 g/kg) and FA (100 mg/kg) improved neurological function and alleviated the infarct volume as well as brain edema in a dose-dependent manner. These changes were accompanied by improved ischemia-induced apoptosis and decreased the inflammatory response. Additionally, chronic treatment with DCH reversed MCAO-induced spatial cognitive deficits in a manner associated with enhanced neurogenesis and increased the expression of brain-derived neurotrophic factor in lesions of the hippocampus. These findings suggest that DCH has the ability to recover cognitive impairment and offer neuroprotection against cerebral ischemic injury via inhibiting microenvironmental inflammation and triggering of neurogenesis in the hippocampus. FA could be one of the potential active compounds

Genome-wide transcriptome analysis of gametophyte development in Physcomitrella patens

<p>Abstract</p> <p>Background</p> <p>Regulation of gene expression plays a pivotal role in controlling the development of multicellular plants. To explore the molecular mechanism of plant developmental-stage transition and cell-fate determination, a genome-wide analysis was undertaken of sequential developmental time-points and individual tissue types in the model moss <it>Physcomitrella patens </it>because of the short life cycle and relative structural simplicity of this plant.</p> <p>Results</p> <p>Gene expression was analyzed by digital gene expression tag profiling of samples taken from <it>P. patens </it>protonema at 3, 14 and 24 days, and from leafy shoot tissues at 30 days, after protoplast isolation, and from 14-day-old caulonemal and chloronemal tissues. In total, 4333 genes were identified as differentially displayed. Among these genes, 4129 were developmental-stage specific and 423 were preferentially expressed in either chloronemal or caulonemal tissues. Most of the differentially displayed genes were assigned to functions in organic substance and energy metabolism or macromolecule biosynthetic and catabolic processes based on gene ontology descriptions. In addition, some regulatory genes identified as candidates might be involved in controlling the developmental-stage transition and cell differentiation, namely MYB-like, HB-8, AL3, zinc finger family proteins, bHLH superfamily, GATA superfamily, GATA and bZIP transcription factors, protein kinases, genes related to protein/amino acid methylation, and auxin, ethylene, and cytokinin signaling pathways.</p> <p>Conclusions</p> <p>These genes that show highly dynamic changes in expression during development in <it>P. patens </it>are potential targets for further functional characterization and evolutionary developmental biology studies.</p