4,905 research outputs found

    Online-to-offline (O2O) Platforms, Proprietary Platforms and Firm Performance

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    This paper studies the impact of O2O (Online-to-offline) platforms on the performance of participating firms. Specifically, the study uses a sample of 3406 cinemas to investigate the moderating effect of O2O platforms, particularly proprietary platforms, on the relationship between cinemas’ resources and their performance. Resources are measured in two dimensions. One dimension is physical resources, measured by the number of seats, while the other dimension is intangible resources, measured by the operating duration of a cinema. The findings show that both O2O platforms and proprietary platforms have significantly positive impact on the relationship between the number of seats and firm performance. O2O platforms negatively moderate the relationship between duration and firm performance, while proprietary platforms positively moderate the relationship. Implications of the findings are discussed

    Anti-thrombotic and anti-tumor effect of water extract of caulis of Sargentodoxa cuneata (Oliv) Rehd et Wils (Lardizabalaceae) in animal models

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    Purpose: To investigate the anti-thrombosis and anti-tumor effect of the water extract of the caulis of Sargentodoxa cuneata (Oliv.) Rehd. et Wils. (WCSW) in rat and mouse models.Methods: WCSW extract was prepared and the main constituents were determined by high pressure liquid chromatography (HPLC). The acute toxicity of the extract was determined in mice. Platelet aggregation in rat platelet-rich plasma (PRP) was examined to evaluate the effect of the extract on platelet function. Thereafter, the cytotoxic activity of WCSW on HL60, A549, S180 and H22 cells was determined by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. In vivo antitumor effect of WCSW was further evaluated on H22 cells transplanted in mice, while the expression of caspase-3, caspase-9, Bcl-2 and Bax proteins were assayed by Western blot analysis.Results: Protocatechuic acid, rhodiola glucoside and chlorogenic acid were identified as the main constituents of WCSW. Platelet aggregation was significantly inhibited by treatment with the extract at concentrations of 1, 5 and 10 mg/mL. WCSW also showed significant inhibitory effect on HL60, A549, S180 and H22 cells in vitro with half maximal inhibitory concentration (IC50 value of 321.9, 285.0, 130.3 and 76.1 μg/mL, respectively. Furthermore, WCSW exhibited obvious anti-tumor effect on H22 transplanted tumor in vivo. After treatment with WCSW, caspase-3, caspase-9 and Bax were significantly (p < 0.05) up-regulated, whereas Bcl-2 was significantly (p < 0.05) down-regulated in the tumor tissues.Conclusion: WCSW possesses significant antithrombosis and anti-tumor effect, and therefore, has the potentials to be developed into effective drugs for clinical treatment of cancer and thrombosis diseases.Keywords: Sargentodoxa cuneata, Anti-thrombosis, Anti-tumor, Platelet aggregation, Apoptosis, Caspase, Protocatechuic acid, Rhodiola glucoside, Chlorogenic aci

    Diagnosis of the Coenosia pedella-group (Diptera: Muscidae), with descriptions of three new species from China

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    The Coenosia pedella-group is established and defined by the combination of the following characters: most species have one presutural dorsocentral seta, costa reaching the tip of media vein, abdomen with distinct spots, hind tibia with dorsal setae, lower calypter at least subequal in length to upper calypter, basis of cerci and surstyli of male short, length of cerci at most four times as long as its width, most of cerci enlarged in distal 1/3 and surstyli subtriangular with width of basal part longer than 1/3 of length. Three new species are described: C. disclambosa Xue & Wang sp. n., C. maoershanensis Xue & Wang sp. n. and C. sublacteipennis Xue&Wang sp. n. A key to the males of Palaearctic Region species of the Coenosia pedella-group is given

    Three new species of the Phaonia acerba group (Diptera: Muscidae) from Palaearctic and Oriental Regions

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    Three new species of the Phaonia acerba group fromthe Palaearctic and Oriental Regions are described: P. gaoligongshanensis Xue & Yu, sp. n., P. zhangxianggi Xue & Yu, sp. n. and P. hongkuii Xue & Yu, sp. n. An identification key to the males of 8 species of the Phaonia acerba group from the Palaearctic and Oriental Regions is provided

    Research Progress and Future Prospect of Dance Movement Therapy in China Based on a Citespace Visual Analysis

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    The purpose of this study was to (1) explore the research progress of dance movement therapy in China and (2) reveal future development trend of dance movement therapy. With the methods of literature review, logical induction and scientific knowledge mapping, the research results of dance movement therapy in China were analyzed visually. The co-occurrence chart of key words and timeline analysis chart of key words of dance movement therapy in China were created based on the data. The co-occurrence chart of key words showed that the research hotspots centered on dance therapy , psychotherapy , Parkinson\u27s disease , autism , special children , teenagers , college students and college students . The subjects of dance therapy were mainly special children, teenagers and college students. The diseases of dance therapy focused on Parkinson\u27s disease , schizophrenia , autism , social anxiety . Timeline analysis chart of key words showed that research subjects experienced trended from psychotherapy , autism to Parkinson\u27s disease and dance decompression . The patients in the study expanded from college students and autistic children to teenagers and college students . The auxiliary elements of dance therapy experienced the expansion from dance to music and art . On the basis of summarizing the experience gained from clinical practice, we should further clarify the operational definition and effect evaluation of dance therapy, and establish a complete and systematic dance analysis system. We should explore how to combine drug therapy with dance therapy, and study the best proportion of the two in the treatment. Under the background of the combination of medicine and sports, we should think about how to promote dance therapy, integrate dance therapy into disease prevention and treatment, and accelerate the advancement of the dance therapy industry
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