Demographic characteristics of study population.

<p>Demographic characteristics of study population.</p

Demographic characteristics of study population.

<p>Demographic characteristics of study population.</p

Association between body mass index z score at baseline and five-year change in pulse wave velocity (upper panel) and diastolic blood pressure (lower panel).

<p>Association between body mass index z score at baseline and five-year change in pulse wave velocity (upper panel) and diastolic blood pressure (lower panel).</p

Anthropometry and vascular measurements at baseline and five-year follow-up in obese/overweight and lean controls.

*<p> = p<0.05, † = p<0.01, ‡ = p<0.001 represents differences between baseline and follow-up within groups, p-values presented as numbers in the last column represents difference in change from baseline to follow-up between groups.</p><p>Wilcoxon signed ranks test was used for related samples, Independent samples median test was used for between – groups comparison. Values are presented as median (min–max). BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, IMT: intima media thickness.</p

sj-docx-1-tpp-10.1177_20451253221135363 – Supplemental material for Classic psychedelics, health behavior, and physical health

Supplemental material, sj-docx-1-tpp-10.1177_20451253221135363 for Classic psychedelics, health behavior, and physical health by Otto Simonsson, Peter S. Hendricks, Richard Chambers, Walter Osika and Simon B. Goldberg in Therapeutic Advances in Psychopharmacology</p

Comparison between burnout patients and controls regarding rated regulation success across task instructions.

<p>The burnout group rated themselves as generally less successful at implementing the task instruction after viewing negative pictures. * = p<.05, # = p<.1.</p

Demographics.

<p>Age and education are expressed in years; MBI-GS is a questionnaire to score perceived work-related stress. Raw 3 indicates the mean total score, raw 4–5 the sub-scores for the exhaustion and cynicism. MADRS = Montgomery Asberg Depression Scale. There was no overall group difference in cortisol levels (p = 0.56; F = 0.08, repeated measure ANOVA). Time of the day for cortisol samples: <i>Sample 1</i>: 06.30–07.30; <i>Sample 2</i>: 15 minutes after sample 1; <i>Sample 3</i>: 30 minutes after sample 1; <i>Sample 4</i>: 12.00–13.00; <i>Sample 5</i>: 15.00–16.00; <i>Sample 6</i>: 20.00–21.00. <i>Sample 7</i>: 22.30–23.30.</p><p>Demographics.</p

Group difference in resting state functional connectivity from the right amygdala (R amy).

<p>Red clusters were calculated from the burnout group - control-group contrast (A), and blue clusters from the reverse contrast (B), (p<0.05 FWE corrected). Clusters are superimposed on the grey matter template (in the MNI space) from the entire study group. (C) Within group connectivity (positive) from the right amygdala. Blue clusters show connectivity clusters in controls, red clusters in the burnout group.</p

Overview of one experimental trial with the maintain instruction.

<p>Participants were presented with a picture, which was replaced by an instruction cue. For negative picture trials, this cue indicated whether the participants' task was to maintain (horizontal arrow), down- regulate (downward arrow) or enhance (upward arrow) their emotional response. Immediately following the instruction cue, participants implemented the regulation instruction while being exposed to the same picture again. Lastly, participants rated how well they managed to implement the regulation instruction on a scale of 1–7.</p

Comparison between burnout patients and controls regarding startle reactions across task instructions.

<p>The burnout group displayed overall higher responses when implementing instructions during negative pictures and this pattern was particularly pronounced during down- regulation of negative emotion. Note that the y-axis represents post-instruction response – pre- instruction response; * = p<.05.</p