693 research outputs found

    Accessing network databases via SQL transactions in a multi-model database system

    Get PDF
    http://archive.org/details/accessingnetwork00walpN

    Unbound states of 32Cl and the 31S(p,\gamma)32Cl reaction rate

    Get PDF
    The 31S(p,\gamma)32Cl reaction is expected to provide the dominant break-out path from the SiP cycle in novae and is important for understanding enrichments of sulfur observed in some nova ejecta. We studied the 32S(3He,t)32Cl charge-exchange reaction to determine properties of proton-unbound levels in 32Cl that have previously contributed significant uncertainties to the 31S(p,\gamma)32Cl reaction rate. Measured triton magnetic rigidities were used to determine excitation energies in 32Cl. Proton-branching ratios were obtained by detecting decay protons from unbound 32Cl states in coincidence with tritons. An improved 31S(p,\gamma)32Cl reaction rate was calculated including robust statistical and systematic uncertainties

    RNAi suppression of xylan synthase genes in wheat starchy endosperm

    Get PDF
    The xylan backbone of arabinoxylan (AX), the major cell wall polysaccharide in the wheat starchy endosperm, is synthesised by xylan synthase which is a complex of three subunits encoded by the GT43_1, GT43_2 and GT47_2 genes. RNAi knock-down of either GT43_1 or all three genes (triple lines) resulted in decreased AX measured by digestion with endoxylanase (to 33 and 34.9% of the controls) and by monosaccharide analysis (to 45.9% and 47.4% of the controls) with greater effects on the amount of water-extractable AX (to 20.6 and 19.9% of the controls). Both sets of RNAi lines also had greater decreases in the amounts of substituted oligosaccharides released by digestion of AX with endoxylanase than in fragments derived only from the xylan backbone. Although the GT43_1 and triple lines had similar effects on AX they did differ in their contents of soluble sugars (increased in triple only) and on grain size (decreased in triple only). Both sets of transgenic lines had decreased grain hardness, indicating effects on cell wall mechanics. These results, and previously published studies of RNAi suppression of GT43_2 and GT47_2 and of a triple mutant of GT43_2, are consistent with the model of xylan synthase comprising three subunits one of which (GT47_2) is responsible for catalysis with the other two subunits being required for correct functioning but indicate that separate xylan synthase complexes may be responsible for the synthesis of populations of AX which differ in their structure and solubility

    Global health competencies in UK postgraduate medical training: a scoping review and curricular content analysis

    Get PDF
    ObjectiveTo assess global health (GH) training in all postgraduate medical education in the UK.DesignMixed methodology: scoping review and curricular content analysis using two GH competency frameworks.Setting and participantsA scoping review (until December 2017) was used to develop a framework of GH competencies for doctors. National postgraduate medical training curricula were analysed against this and a prior framework for GH competencies. The number of core competencies addressed and/or appearing in each programme was recorded.OutcomesThe scoping review identified eight relevant publications. A 16-competency framework was developed and, with a prior 5-competency framework, used to analyse each of 71 postgraduate medical curricula. Curricula were examined by a team of researchers and relevant learning outcomes were coded as one of the 5 or 16 core competencies. The number of core competencies in each programme was recorded.ResultsUsing the 5-competency and 16-competency frameworks, 23 and 20, respectively, out of 71 programmes contained no global health competencies, most notably the Foundation Programme (equivalent to internship), a compulsory programme for UK medical graduates. Of a possible 16 competencies, the mean number across all 71 programmes was 1.73 (95% CI 1.42 to 2.04) and the highest number were in paediatrics and infectious diseases, each with five competencies. Of the 16 core competencies, global burden of disease and socioeconomic determinants of health were the two most cited with 47 and 35 citations, respectively. 8/16 competencies were not cited in any curriculum.ConclusionsEquity of care and the challenges of practising in an increasingly globalised world necessitate GH competencies for all doctors. Across the whole of postgraduate training, the majority of UK doctors are receiving minimal or no training in GH. Our GH competency framework can be used to map and plan integration across postgraduate programmes.</jats:sec

    Guiding neutral atoms around curves with lithographically patterned current-carrying wires

    Get PDF
    Laser-cooled neutral atoms from a low-velocity atomic source are guided via a magnetic field generated between two parallel wires on a glass substrate. The atoms bend around three curves, each with a 15-cm radius of curvature, while traveling along a 10-cm-long track. A maximum flux of 2*10^6 atoms/sec is achieved with a current density of 3*10^4 A/cm^2 in the 100x100-micrometer-cross-section wires. The kinetic energy of the guided atoms in one transverse dimension is measured to be 42 microKelvin.Comment: 9 page

    Searching for Long Strings in CMB Maps

    Get PDF
    Using analytical methods and Monte Carlo simulations, we analyze new statistics designed to detect isolated step-like discontinuities which are coherent over large areas of Cosmic Microwave Background (CMB) pixel maps. Such coherent temperature discontinuities are predicted by the Kaiser-Stebbins effect to form due to long cosmic strings present in our present horizon. The background of the coherent step-like seed is assumed to be a scale invariant Gaussian random field which could have been produced by a superposition of seeds on smaller scales and/or by inflationary quantum fluctuations. We find that the proposed statistics can detect the presense of a coherent discontinuity at a sensitivity level almost an order of magnitude better compared to more conventional statistics like the skewness or the kurtosis.Comment: 10 pages, 3 Figures, Use RevTe

    Time to go global: a consultation on global health competencies for postgraduate doctors

    Get PDF
    BACKGROUND: Globalisation is having profound impacts on health and healthcare. We solicited the views of a wide range of stakeholders in order to develop core global health competencies for postgraduate doctors. METHODS: Published literature and existing curricula informed writing of seven global health competencies for consultation. A modified policy Delphi involved an online survey and face-to-face and telephone interviews over three rounds. RESULTS: Over 250 stakeholders participated, including doctors, other health professionals, policymakers and members of the public from all continents of the world. Participants indicated that global health competence is essential for postgraduate doctors and other health professionals. Concerns were expressed about overburdening curricula and identifying what is 'essential' for whom. Conflicting perspectives emerged about the importance and relevance of different global health topics. Five core competencies were developed: (1) diversity, human rights and ethics; (2) environmental, social and economic determinants of health; (3) global epidemiology; (4) global health governance; and (5) health systems and health professionals. CONCLUSIONS: Global health can bring important perspectives to postgraduate curricula, enhancing the ability of doctors to provide quality care. These global health competencies require tailoring to meet different trainees' needs and facilitate their incorporation into curricula. Healthcare and global health are ever-changing; therefore, the competencies will need to be regularly reviewed and updated

    CHERCAM: A Cherenkov imager for the CREAM experiment

    No full text
    International audienceThe CREAM experiment (Cosmic Ray Energetics and Mass) is dedicated to the measurement of the energy spectrum of nuclear elements in cosmic rays, over the range 1012^{12} to 1015^{15} eV. The individual elements separation, which is a key feature of CREAM, requires instruments with strong identification capabilities. A proximity focused type of Cherenkov imager, CHERCAM (CHERenkov CAMera), providing both a good signature of downgoing Z=1 particles and good single element separation through the whole range of nuclear charges [Buénerd et al. 28th ICRC, Tsukuba, OG 1.5, 2003, p. 2157], is under development. After a brief introduction, the main features and the construction status of the CHERCAM are being summarized

    CHERCAM: the Cherenkov imager of the CREAM experiment, results in Z=1 test beams

    No full text
    International audienceThe CREAM experiment investigates the high energy spectrum of nuclear elements from H to Fe in the cosmic ray flux up to 101510^{15} eV, with an instrument designed to achieve individual elements separation over the whole mass range. A proximity focused Cherenkov imager, CHERCAM (CHERenkov CAMera), will provide both a good topological signature (Cherenkov ring) for downgoing Z=1 particles, and a charge independent individual element separation through the considered range of nuclear charges. It will be implemented in the forthcoming CREAM flight 3. The contribution reports on the CHERCAM main features and on the preliminary results from in-beam tests at CERN
    • …
    corecore