Admissibility in the abstract dialectical framework

The aim of this paper is to study the concept of admissibility in abstract dialectical frameworks (ADFs). While admissibility is well-understood in Dung-style frameworks, a generalization to ADFs is not trivial. Indeed, the original proposal turned out to behave unintuitively at certain instances. A recent approach circumvented this problem by using a three-valued concept. In this paper, we propose a novel two-valued approach which more directly follows the original understanding of admissibility. We compare the two approaches and show that they behave differently on certain ADFs. Our results imply that for generalizations of Dung-style frameworks, establishing a precise correspondence between two-valued (i.e. extension-based) and three-value (i.e. labeling-based) characterizations of argumentation semantics is not easy and requires further investigations

Assessment of risks to honey bees posed by guttation

Background: Besides their nectar and pollen collecting activities, honey bees also forage water. Guttation droplets may be used as a water source. Measurements of high residue levels of some intrinsically highly toxic, systemic insecticides in guttation droplets triggered research activities on the potential risk for honey bees. Since 2009, a large number of studies have been conducted on the environmental conditions and factors favoring guttation, foraging of guttation, the occurrence of guttation in different crops, the frequency of guttation events and residue measurements in guttation droplets in different crops, at different growth stages and with different active ingredients. Different approaches of laboratory, semi-field and field studies were set up to address the potential risk of guttation to bees and to gain clarification whether and how this concern would need to be specifically addressed in the risk assessment for bees. Results: Occasionally increased mortalities of worker bees were reported from single events in some trials, when colonies were placed directly next to the sown maize crop treated with a systemic insecticide. However, there were no long-term colony effects (e.g. on colony strength and brood development) reported from any of the realistic worst case exposure trials conducted by either public research institutes or industry. Conclusion: The potential risk for bees is in the first instance dependent on the distance of the colonies to treated crops. Maize is considered as the worst case crop in terms of frequency, duration and intensity of guttation and of residue level of compounds found in guttation liquid. Though increased worker bee mortality on individual days was seen in some of the field studies where hives were placed directly at guttating maize fields, adverse effects to colony vitality, colony and brood development were never observed. Keywords: Guttation, risk assessment, pesticides, honey bees

Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice.

Objective Impaired cardiac efficiency is a hallmark of diabetic cardiomyopathy in models of type 2 diabetes. Adiponectin receptor 1 (AdipoR1) deficiency impairs cardiac efficiency in non-diabetic mice, suggesting that hypoadiponectinemia in type 2 diabetes may contribute to impaired cardiac efficiency due to compromised AdipoR1 signaling. Thus, we investigated whether targeting cardiac adiponectin receptors may improve cardiac function and energetics, and attenuate diabetic cardiomyopathy in type 2 diabetic mice. Methods A non-selective adiponectin receptor agonist, AdipoRon, and vehicle were injected intraperitoneally into Eight-week-old db/db or C57BLKS/J mice for 10 days. Cardiac morphology and function were evaluated by echocardiography and working heart perfusions. Results Based on echocardiography, AdipoRon treatment did not alter ejection fraction, left ventricular diameters or left ventricular wall thickness in db/db mice compared to vehicle-treated mice. In isolated working hearts, an impairment in cardiac output and efficiency in db/db mice was not improved by AdipoRon. Mitochondrial respiratory capacity, respiration in the presence of oligomycin, and 4-hydroxynonenal levels were similar among all groups. However, AdipoRon induced a marked shift in the substrate oxidation pattern in db/db mice towards increased reliance on glucose utilization. In parallel, the diabetes-associated increase in serum triglyceride levels in vehicle-treated db/db mice was blunted by AdipoRon treatment, while an increase in myocardial triglycerides in vehicle-treated db/db mice was not altered by AdipoRon treatment. Conclusion AdipoRon treatment shifts myocardial substrate preference towards increased glucose utilization, likely by decreasing fatty acid delivery to the heart, but was not sufficient to improve cardiac output and efficiency in db/db mice

Curvatures and Tolerances in the Euclidean Motion Group

We investigate the action of imprecisely defined a#ne and Euclidean transformations and compute tolerance zones of points and subspaces. Tolerance zones in the Euclidean motion group are analyzed by means of linearization and bounding the linearization error via the curvatures of that group with respect to an appropriate metric

Analyzing the Computational Complexity of Abstract Dialectical Frameworks via Approximation Fixpoint Theory

Abstract dialectical frameworks (ADFs) have recently been proposed as a versatile generalization of Dung''s abstract argumentation frameworks (AFs). In this paper, we present a comprehensive analysis of the computational complexity of ADFs. Our results show that while ADFs are one level up in the polynomial hierarchy compared to AFs, there is a useful subclass of ADFs which is as complex as AFs while arguably offering more modeling capacities. As a technical vehicle, we employ the approximation fixpoint theory of Denecker, Marek and Truszczyński, thus showing that it is also a useful tool for complexity analysis of operator-based semantics