1,191 research outputs found

    Intelligent systems in the context of surrounding environment

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    We investigate the behavioral patterns of a population of agents, each controlled by a simple biologically motivated neural network model, when they are set in competition against each other in the Minority Model of Challet and Zhang. We explore the effects of changing agent characteristics, demonstrating that crowding behavior takes place among agents of similar memory, and show how this allows unique `rogue' agents with higher memory values to take advantage of a majority population. We also show that agents' analytic capability is largely determined by the size of the intermediary layer of neurons. In the context of these results, we discuss the general nature of natural and artificial intelligence systems, and suggest intelligence only exists in the context of the surrounding environment (embodiment). Source code for the programs used can be found at http://neuro.webdrake.net/

    Open access in theory and practice : the theory-practice relationship and openness

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    Open Access in Theory and Practice investigates the theory-practice relationship in the domain of open access publication and dissemination of research outputs. Drawing on detailed analysis of the literature and current practice in OA, as well as data collected in detailed interviews with practitioners, policymakers, and researchers, the book discusses what constitutes ‘theory’, and how the role of theory is perceived by both theorists and practitioners. Exploring the ways theory and practice have interacted in the development of OA, the authors discuss what this reveals about the nature of the OA phenomenon itself and the theory-practice relationship. Open Access in Theory and Practice contributes to a better understanding of OA and, as such, should be of great interest to academics, researchers, and students working in the fields of information science, publishing studies, science communication, higher education policy, business, and economics. The book also makes an important contribution to the debate of the relationship between theory and practice in information science, and more widely across different fields of the social sciences and humanitie

    Pyrethroids and Their Effects on Ion Channels

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    Flight of the dragonflies and damselflies

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    This work is a synthesis of our current understanding of the mechanics, aerodynamics and visually mediated control of dragonfly and damselfly flight, with the addition of new experimental and computational data in several key areas. These are: the diversity of dragonfly wing morphologies, the aerodynamics of gliding flight, force generation in flapping flight, aerodynamic efficiency, comparative flight performance and pursuit strategies during predatory and territorial flights. New data are set in context by brief reviews covering anatomy at several scales, insect aerodynamics, neuromechanics and behaviour. We achieve a new perspective by means of a diverse range of techniques, including laser-line mapping of wing topographies, computational fluid dynamics simulations of finely detailed wing geometries, quantitative imaging using particle image velocimetry of on-wing and wake flow patterns, classical aerodynamic theory, photography in the field, infrared motion capture and multi-camera optical tracking of free flight trajectories in laboratory environments. Our comprehensive approach enables a novel synthesis of datasets and subfields that integrates many aspects of flight from the neurobiology of the compound eye, through the aeromechanical interface with the surrounding fluid, to flight performance under cruising and higher-energy behavioural modes

    Suppression of properties associated with malignancy in murine melanoma-melanocyte hybrid cells.

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    Murine and human melanoma cells differ relatively reliably from non-tumorigenic melanocytes in certain biological properties. When cultured at low pH, melanocytes tend to be pigmented and melanoma cells unpigmented. The growth of virtually all metastatic melanoma cells is inhibited by phorbol esters such as TPA (12-O-tetradecanoyl phorbol-13-acetate), which stimulate melanocyte growth. Melanocytes fail to grow in suspension culture or produce tumours when implanted in animals, while many melanoma lines can do both. Here we studied which of these properties were dominant in hybrid cells formed by fusion of drug-resistant murine B16-F10RR melanoma cells to melanocytes of the albino and brown lines, melan-c and melan-b. The albino melanocytes are unpigmented but well-differentiated, the brown melanocytes produce pale brown pigment and the melanoma cells are unpigmented under the conditions used. All hybrid colonies observed produced black pigment, except some melan-b/melanoma hybrids when growing sparsely with TPA. Thus pigmentation was generally dominant. 14/15 hybrid lines showed stimulation of proliferation by TPA, as do melanocytes. Most hybrid lines showed no or reduced capacity for growth in suspension, though some grew better in suspension when TPA was present. There was marked suppression of the tumorigenicity of the parental melanoma cells in 4/8 hybrids examined, and tumorigenicity was reduced in the others, despite considerable chromosome loss by the passage level tested. Thus most properties of the non-tumorigenic pigment cells were dominant, as often observed for other cell lineages, and providing further evidence for gene loss in the genesis of malignant melanoma

    Phasing of dragonfly wings can improve aerodynamic efficiency by removing swirl

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    Dragonflies are dramatic, successful aerial predators, notable for their flight agility and endurance. Further, they are highly capable of low-speed, hovering and even backwards flight. While insects have repeatedly modified or reduced one pair of wings, or mechanically coupled their fore and hind wings, dragonflies and damselflies have maintained their distinctive, independently controllable, four-winged form for over 300 Myr. Despite efforts at understanding the implications of flapping flight with two pairs of wings, previous studies have generally painted a rather disappointing picture: interaction between fore and hind wings reduces the lift compared with two pairs of wings operating in isolation. Here, we demonstrate with a mechanical model dragonfly that, despite presenting no advantage in terms of lift, flying with two pairs of wings can be highly effective at improving aerodynamic efficiency. This is achieved by recovering energy from the wake wasted as swirl in a manner analogous to coaxial contra-rotating helicopter rotors. With the appropriate fore–hind wing phasing, aerodynamic power requirements can be reduced up to 22 per cent compared with a single pair of wings, indicating one advantage of four-winged flying that may apply to both dragonflies and, in the future, biomimetic micro air vehicles

    A laterally-fused N-heterocyclic carbene framework from polysubstituted aminoimidazo[5,1-b]oxazol-6-ium salts

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    A polysubstituted 3-aminoimidazo[5,1-b]oxazol-6-ium framework has been accessed from a new nitrenoid reagent by a two-step ynamide annulation and imidazolium ring-formation sequence. Metalation with Au(I), Cu(I) and Ir(I) at the C2 position provides an L-shaped NHC ligand scaffold that has been validated in gold-catalysed alkyne hydration and arylative cyclisation reactions

    Close space sublimation of CdTe for solar cells and the effect of underlying layers

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    This work has focused on the design, construction and testing of a close space sublimation system for CdTe deposition. In addition, it also focused on variations to the treatment and fabrication procedures of the transparent conducting oxide and CdS layers prior to the CdTe deposition, in order to influence the structure and electrical properties of the CdTe/CdS interface. CdTe was deposited by the physical vapour process, close space sublimation. The equipment used was custom built for this work and is therefore described in detail. Some of the deposition parameters of the equipment were varied in order to allow a comparison between the equipment in this work and those reported in the literature. Bilayers of CdS have been created by depositing two individual CdS layers, on top of one another, whilst also varying the annealing treatment of the first layer. These bilayers were included in devices and which subsequently underwent a series of etches to allow analysis of the materials. The bilayers were shown to effect the preferred orientation of the CdTe layer deposited on top, but the results suggested the bilayers had a negative effect on the amount of current recombination in the depletion region. The roughness of the transparent conducting oxide coated glass substrates used in this work, was proposed as a way of influencing the roughness of the CdS layer deposited on top and therefore the roughness of the layer the CdTe is deposited on. It was proposed that the CdTe material deposited on a roughened substrate may have an increased grain size; no evidence for this was found for samples including CdS layers. A second phase of CdTe was observed and assigned to the presence of a CdSxTe1−x alloy. The sulphur content of the alloy was found to increase as the roughness of the substrate increased. CdS was deposited by the wet chemistry process chemical bath deposition. In situ monitoring of the deposition was carried out by studying the re ection of light from the interface at the end of an optical fibre placed within the solution. The results indicated that the in situ monitoring was sensitive to the initial deposition but the sensitivity reduced as the film thickness approached 150 nm. The in situ monitoring technique and ellipsometry measurements of the CdS showed good agreement with the theory of two deposition mechanisms occurring during the deposition. The results showed that CdS grown by chemical bath deposition has a two layer structure consistent with; a low density CdS grown by homogeneous deposition, on top of dense CdS grown by ion by ion deposition. An ellipsometry model for the CdS and CdTe layers is presented, along with its optical properties over the wavelength range 245 to 1690 nm.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
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