510 research outputs found

    Invertible Kernel PCA with Random Fourier Features

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    Kernel principal component analysis (kPCA) is a widely studied method to construct a low-dimensional data representation after a nonlinear transformation. The prevailing method to reconstruct the original input signal from kPCA -- an important task for denoising -- requires us to solve a supervised learning problem. In this paper, we present an alternative method where the reconstruction follows naturally from the compression step. We first approximate the kernel with random Fourier features. Then, we exploit the fact that the nonlinear transformation is invertible in a certain subdomain. Hence, the name \emph{invertible kernel PCA (ikPCA)}. We experiment with different data modalities and show that ikPCA performs similarly to kPCA with supervised reconstruction on denoising tasks, making it a strong alternative.Comment: This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessibl

    S. derby infection in Swedish pig herds

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    Within the Swedish salmonella control program any findings of salmonella is compulsory notifiable. In all Salmonella infected herds an official veterinary officer will perform an investigation and supervise the clearance of Salmonella infection/contamination from the farm (Wierup, M. 1991). Infected farms are subjected to restrictions including prohibition of movement of live animals except for transport to sanitary slaughter

    Salmonella Isolated from Animals and Feed Production in Sweden Between 1993 and 1997

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    This paper presents Salmonella data from animals, feedstuffs and feed mills in Sweden between 1993 and 1997. During that period, 555 isolates were recorded from animals, representing 87 serotypes. Of those, 30 serotypes were found in animals in Sweden for the first time. The majority of all isolates from animals were S. Typhimurium (n = 91), followed by S. Dublin (n = 82). There were 115 isolates from cattle, 21 from broilers, 56 from layers and 18 from swine. The majority of these isolates were from outbreaks, although some were isolated at the surveillance at slaughterhouses. The number of isolates from the feed industry was similar to that of the previous 5-year period. Most of those findings were from dust and scrapings from feed mills, in accordance with the HACCP programme in the feed control programme. It can be concluded that the occurrence of Salmonella in animals and in the feed production in Sweden remained favourable during 1993–97

    Fixed-Parameter Tractability of Multicut in Directed Acyclic Graphs

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    The Multicut problem, given a graph G, a set of terminal pairs T={(si,ti) ∣ 1≀i≀r}\mathcal{T}=\{(s_i,t_i)\ |\ 1\leq i\leq r\}, and an integer pp, asks whether one can find a cutset consisting of at most pp nonterminal vertices that separates all the terminal pairs, i.e., after removing the cutset, tit_i is not reachable from sis_i for each 1≀i≀r1\leq i\leq r. The fixed-parameter tractability of Multicut in undirected graphs, parameterized by the size of the cutset only, has been recently proved by Marx and Razgon [SIAM J. Comput., 43 (2014), pp. 355--388] and, independently, by Bousquet, Daligault, and ThomassĂ© [Proceedings of STOC, ACM, 2011, pp. 459--468], after resisting attacks as a long-standing open problem. In this paper we prove that Multicut is fixed-parameter tractable on directed acyclic graphs when parameterized both by the size of the cutset and the number of terminal pairs. We complement this result by showing that this is implausible for parameterization by the size of the cutset only, as this version of the problem remains W[1]W[1]-hard

    The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation

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    Proteolysis mediated by matrix metalloproteinases (MMPs) and serine proteinases is associated with cancer invasion and metastasis. Activation of latent proMMPs, and especially the proforms of the type IV collagen degrading gelatinases A and B (proMMP-2 and proMMP-9), is thought to be a critical step in this process. We have recently found that human tumour-associated trypsin-2 is a potent activator of proMMP-9 and it also activates proMMP-2 in vitro. Trypsinogen, MMP-2, and MMP-9 are expressed in ovarian cancer. To elucidate the function of trypsin in vivo, we studied whether high concentrations of trypsinogen-1, trypsinogen-2, their α1-proteinase inhibitor (API) complexes, and tumour-associated trypsin inhibitor (TATI) are associated with proMMP-2 and proMMP-9 activation in ovarian tumour cyst fluids. Zymography and immunofluorometric analysis of 61 cyst fluids showed a significant association between high trypsin concentrations and the activation of MMP-9 (P= 0.003–0.05). In contrast, the trypsin concentrations were inversely associated with the activation of MMP-2 (P= 0.01–0.02). Immunohistochemical analysis of ovarian tumour tissue demonstrated expression of trypsinogen-2 and TATI in the secretory epithelium. MMP-2 was detected both in stromal and epithelial cells whereas MMP-9 was detected in neutrophils and macrophage-like cells in stromal and epithelial areas. These results suggest that trypsin may play a role in the regulation of the MMP-dependent proteolysis associated with invasion and metastasis of ovarian cancer. © 2001 Cancer Research Campaign www.bjcancer.co

    Extreme ultraviolet interferometry measurements with high-order harmonics

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    We demonstrate that high-order harmonics generated by short, intense laser pulses in gases provide an interesting radiation source for extreme ultraviolet interferometry, since they are tunable, coherent, of short pulse duration, and simple to manipulate. Harmonics from the 9th to the 15th are used to measure the thickness of an aluminum layer. The 11th harmonic is used to determine the spatial distribution of the electron density of a plasma produced by a 300-ps laser. Electronic densities higher than 2-10(20) electrons/cm(3) are measured. (C) 2000 Optical Society of America. OCIS codes: 190.0190, 190.4160, 190.7110, 120.3180, 140.7240, 350.4500
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