1,929 research outputs found

    Teaching American Constitutional Law in Poland

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    Teaching American Constitutional Law in Poland

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    A survey of soil invertebrates in two aspen forests in northern Minnesota

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    Information Systems and Assemblages

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    International audienceThe theme for the 2014 IFIP WG 8.2 working conference was ‘Information Systems and Global Assemblages: (Re)Configuring Actors, Artefacts, Organizations’. The motivation behind the choice of the conference theme has been the increasing appreciation of notions of emergence, heterogeneity and temporality in IS studies. We found that the conference provided an opportune occasion for inviting scholars interested in exploring these notions, their relevance and promise for IS studies. The concept of the ‘assemblage’ [1], already referenced in IS studies, as will be discussed below, and with significant popularity in other fields, such as anthropology, geography and cultural studies, provided the stepping stone for approaching the heterogeneous, emergent and situated nature of information systems and organization. In particular, we opted for highlighting the ‘global assemblage’[2] as a metaphor to talk about challenging yet often creative tensions that emerge as global imperatives (geographical, intellectual, procedural and others) interact with local arrangements of actors, artefacts and organizations. Here ‘global’ does not mean universal or everywhere, but mobile, abstractable, and capable of recontextualization across diverse social and cultural situations.This book provides a collection of contributions by scholars who responded to our invitation, adding depth and breadth to our understanding of the concept and its value for IS studies. At the same time, some contributors chose to discuss emergence, heterogeneity and situatedness in different terms, drawing upon alternative theoretical traditions and concepts. The result has been an engaging and stimulating mix of ideas that points towards the ‘multiple’ trajectories - current and future - of this exciting stream of research

    The state of the art of teaching research methods in the social sciences : towards a pedagogical culture

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    No formal pedagogical culture for research methods in the social sciences seems to exist and, as part of the authors' endeavour to establish such a culture, this article reviews current literature about teaching research methods and identifies the gaps in the research. Articles in academic journals spanning a 10-year period were collected by searching academic catalogues and compiling a database of 195 articles published in 61 journals. These articles were reviewed and are discussed according to seven themes. Three specific gaps in research are identified that indicate some new agendas for research on teaching research methods in the social sciences. The implications for developing a pedagogical culture for research methods from the current literature reviewed are discussed

    Topotecan distribution in an anephric infant with therapy resistant bilateral Wilms tumor with a novel germline WT1 gene mutation

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    The therapeutic strategy for bilateral Wilms tumor (WT) remains a challenge. Especially in cases with chemotherapy resistant disease, bilateral nephrectomy is sometimes inevitable. For optimal cure rates stage V WT patients benefit from adjuvant treatment; however, there are limited data available on chemotherapy pharmacokinetics in anephric children. In this report, we describe a 10-month old girl with bilateral Wilms tumor and a novel germline WT1 gene mutation. This patient hardly showed any response on preoperative chemotherapy, and ultimately, underwent sequential bilateral tumor-nephrectomy. Subsequently, during peritoneal dialysis, she received topotecan as adjuvant chemotherapy based on plasma levels, indicating that this is a reasonable option as adjuvant treatment in therapy-resistant Wilms tumor patients after bilateral nephrectomy. This case showed a novel germline WT1 gene mutation of which the correlation with resistant phenotype has to be confirmed in larger cohorts of WT patients

    The phase relation between sunspot numbers and soft X-ray flares

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    To better understand long-term flare activity, we present a statistical study on soft X-ray flares from May 1976 to May 2008. It is found that the smoothed monthly peak fluxes of C-class, M-class, and X-class flares have a very noticeable time lag of 13, 8, and 8 months in cycle 21 respectively with respect to the smoothed monthly sunspot numbers. There is no time lag between the sunspot numbers and M-class flares in cycle 22. However, there is a one-month time lag for C-class flares and a one-month time lead for X-class flares with regard to sunspot numbers in cycle 22. For cycle 23, the smoothed monthly peak fluxes of C-class, M-class, and X-class flares have a very noticeable time lag of one month, 5 months, and 21 months respectively with respect to sunspot numbers. If we take the three types of flares together, the smoothed monthly peak fluxes of soft X-ray flares have a time lag of 9 months in cycle 21, no time lag in cycle 22 and a characteristic time lag of 5 months in cycle 23 with respect to the smoothed monthly sunspot numbers. Furthermore, the correlation coefficients of the smoothed monthly peak fluxes of M-class and X-class flares and the smoothed monthly sunspot numbers are higher in cycle 22 than those in cycles 21 and 23. The correlation coefficients between the three kinds of soft X-ray flares in cycle 22 are higher than those in cycles 21 and 23. These findings may be instructive in predicting C-class, M-class, and X-class flares regarding sunspot numbers in the next cycle and the physical processes of energy storage and dissipation in the corona.Comment: 8 pages, 3 figures, Accepted for publication in Astrophysics & Space Scienc

    Counter-Mapping as Assemblage: Reconfiguring Indigeneity

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    Part 2: Ethnographic Accounts of IS UseInternational audienceThis paper explores the utility of assemblage theory for intergenerational counter-mapping and, through this, for reconfigurations of indigeneity. Counter-mapping is theorised as a kind of assemblage that, through intergenerational learning, is fundamentally memetic (composed of evolving units of information) in nature. Assemblage is theorised as having three aspects (relations of exteriority, meshworks and memes) for reconfiguring indigeneity in line with spatio-temporal aspects of memes. Counter-mapping assemblages are explored with examples of First Nations’ (indigenous peoples residing in Canada) political and commemorative activity. Kaachewaapechuu, a long commemorative walk in the northern Quebec Cree village of Wemindji, acts as a case study for exploring how assemblages-as-memes can be used to theorise new kinds of counter-mapping that reconfigure indigenous commemoration precisely as political, and therefore as not separate from more media-driven aspects of Canadian politics, including those concerning its First Nations. Global positioning systems and Google Earth mapping platforms were used during the primary author’s participation in kaachewaapechuu, providing for the exploration of new media platforms upon which such a re-theorised politics might be envisioned

    Detection of antibacterial activity of essential oil components by TLC-bioautography using luminescent bacteria

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    The aim of the present study was the chemical characterization of some medically relevant essential oils (tea tree, clove, cinnamon bark, thyme and eucalyptus) and the investigation of antibacterial effect of the components of these oils by use of a direct bioautographic method. Thin layer chromatography (TLC) was combined with biological detection in this process. The chemical composition of the oils was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Eucalyptol (84.2%) was the main component of the essential oil of eucalyptus, eugenol (83.7%) of clove oil, and trans-cinnamic aldehyde (73.2%), thymol (49.9%) and terpinen-4-ol (45.8%) of cinnamon bark, thyme and tea tree oils, respectively. Antibacterial activity of the separated components of these oils, as well as their pure main components (eucalyptol, eugenol, trans-cinnamic aldehyde and thymol) was observed against the Gram-negative luminescence tagged plant pathogenic bacterium Pseudomonas syringae pv. maculicola (Psmlux) and the Gram-negative, naturally luminescent marine bacterium Vibrio fischeri. On the whole, the antibacterial activity of the essential oils could be related to their main components, but the minor constituents may be involved in this process. Trans-cinnamic aldehyde and eugenol were the most active compounds in TLC-bioautography. The sensitivity of TLC-bioautographic method can be improved with using luminescent test bacteria. This method is more cost-effective and provides more reliable results in comparison with conventional microbiological methods, e.g. disc-diffusion technique
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