The Tennessee Death Penalty: Prosecutors, Juries and the Impact of Race

The impact of race within the American criminal justice system has seen long-term debate and has been studied by numerous social scientists. This dissertation examines the criminal justice system by analyzing data created by the Tennessee courts to determine whether race impacts the administration of Tennessee’s death penalty. This dissertation examines whether race impacts the overall administration of Tennessee’s death penalty, a Tennessee prosecutor’s decision to seek death, and a Tennessee jury’s decision to impose death. The impact of race at each stage is analyzed by logistic regression to isolate the defendant’s race, the victim’s race, and the racial interaction between them. Prior empirical research shows black defendants whose victims are white are more likely to receive death than white defendants whose victims are white. Prior research shows defendants whose victims are white, regardless of the race of the defendant, are more likely to receive death than when victims are black. The regression analyses reveal after controlling for heinousness of crime and the defendant’s dangerousness that race is not a predictive factor in whether defendants are sentenced to death in the overall application of the death penalty. The findings show that white victim murders, irrespective of the defendant’s race, have slight predictive power in whether prosecutors seek the death penalty, but white victim cases have the least predictive power of all variables that impact prosecutorial decisions. Murders involving black defendants and white victims, irrespective of their racial relationship, decrease the likelihood a jury will return a death sentence. When testing the racial interaction of defendants and victims, the only relationship that is a significant predictor in the Tennessee death penalty are murders with white defendants and white victims. Based on qualitative data from interviews with Knox County criminal court judges, this can be explained by heinousness of crime

Baker Center Journal of Applied Public Policy - Vol. IV, No. I

This is the 4th volume of the Baker Center Journal on Applied Public Policy. It includes articles on nuclear nonproliferation, American political development, election issues, Tennessee state trial courts, attitudes related to rich and poor people, and two student articles on science, innovation, technology and economic growth and explosive trace detection at airports

Imidazolium Salts as Small-Molecule Urinary Bladder Exfoliants in a Murine Model

We present a novel family of small-molecule urinary bladder exfoliants that are expected to be of great value in preclinical studies of urologic conditions and have improved potential for translation compared with prior agents. There is broad urologic interest in the therapeutic potential of such exfoliating agents. The primary agent used in preclinical models, the cationic peptide protamine sulfate (PS), has limited translational potential due to concerns including systemic adverse reactions and bladder tissue injury. Intravesical application of a safe, systemically nontoxic exfoliant would have potential utility in the eradication of Escherichia coli and other uropathogens that reside in the bladder epithelium following cystitis, as well as in chronic bladder pain and bladder cancer. Here, we introduce a family of imidazolium salts with potent and focused exfoliating activity on the bladder epithelium. Synthesis and purification were straightforward and scalable, and the compounds exhibited prolonged stability in lyophilized form. Most members of the compound family were cytotoxic to cultured uroepithelial cells, with >10-fold differences in potency across the series. Upon topical (intravesical) administration of selected compounds to the murine bladder, complete epithelial exfoliation was achieved with physiologically relevant imidazolium concentrations and brief contact times. The exfoliative activity of these compounds was markedly improved in comparison to PS, as assessed by microscopy, immunofluorescence, and immunoblotting for uroplakins. Bladder uroepithelium regenerated within days to yield a histologically normal appearance, and no toxicity was observed. Finally, the chemical scaffold offers an opportunity for inclusion of antimicrobials or conjugation with chemotherapeutic or other moieties

Radical Discrimination in the Death Penalty in Tennessee: An Empirical Assessment

The intense media coverage of the United States Supreme Court\u27s recent decisions in Baze v. Rees\u27 and Kennedy v. Louisiana highlights the ongoing saliency of the death penalty in American politics. In this article, we use empirical evidence to shed light on this controversy. Our analysis utilizes data from 1,068 first-degree murder convictions rendered in Tennessee between 1977 and 2007. The questions animating our research are: 1) What factors led prosecutors to seek the death penalty? and 2) What factors led juries to impose it? In particular, we are interested in the role that race plays in these decisions. Does the system operate in a racially-neutral fashion, or is it hopelessly infected with discrimination, as some prior studies in other states have suggested

Race and the Death Penalty: an Empirical Assessment of First Degree Murder Convictions in Tennessee after Gregg v. Georgia

We analyze over 1,000 first-degree murder convictions in the state of Tennessee from 1977 through 2007 to determine if either “race-of-defendant” or “race-of-victim” effects are present when it comes to the application of capital punishment. We control for numerous factors related to the demographics of offender and victim, as well as the circumstances of the crime itself and the availability of evidence. Our primary findings note that prosecutors are more likely to seek a death sentence when a victim is white, but we also find that juries are not affected by the race of the victim. We also find no systematic bias against African-American defendants from prosecutors or juries. We identify a number of other variables that do have strong relationship to the imposition of the death penalty, including presence of scientific evidence, prior criminal convictions, and the killing of a law enforcement officer

Preparation and <i>in Vitro</i> Antimicrobial Activity of Silver-Bearing Degradable Polymeric Nanoparticles of Polyphosphoester-<i>block</i>-Poly(l‑lactide)

The development of well-defined polymeric nanoparticles (NPs) as delivery carriers for antimicrobials targeting human infectious diseases requires rational design of the polymer template, an efficient synthetic approach, and fundamental understanding of the developed NPs, <i>e.g.,</i> drug loading/release, particle stability, and other characteristics. Herein, we developed and evaluated the <i>in vitro</i> antimicrobial activity of silver-bearing, fully biodegradable and functional polymeric NPs. A series of degradable polymeric nanoparticles (dNPs), composed of phosphoester and l-lactide and designed specifically for silver loading into the hydrophilic shell and/or the hydrophobic core, were prepared as potential delivery carriers for three different types of silver-based antimicrobials–silver acetate or one of two silver carbene complexes (SCCs). Silver-loading capacities of the dNPs were not influenced by the hydrophilic block chain length, loading site (<i>i.e.</i>, core or shell), or type of silver compound, but optimization of the silver feed ratio was crucial to maximize the silver loading capacity of dNPs, up to <i>ca.</i> 12% (w/w). The release kinetics of silver-bearing dNPs revealed 50% release at <i>ca.</i> 2.5–5.5 h depending on the type of silver compound. In addition, we undertook a comprehensive evaluation of the rates of hydrolytic or enzymatic degradability and performed structural characterization of the degradation products. Interestingly, packaging of the SCCs in the dNP-based delivery system improved minimum inhibitory concentrations up to 70%, compared with the SCCs alone, as measured <i>in vitro</i> against 10 contemporary epidemic strains of Staphylococcus aureus and eight uropathogenic strains of Escherichia coli. We conclude that these dNP-based delivery systems may be beneficial for direct epithelial treatment and/or prevention of ubiquitous bacterial infections, including those of the skin and urinary tract