939 research outputs found
Aerodynamic performance investigation of advanced mechanical suppressor and ejector nozzle concepts for jet noise reduction
Advanced Supersonic Transport jet noise may be reduced to Federal Air Regulation limits if recommended refinements to a recently developed ejector shroud exhaust system are successfully carried out. A two-part program consisting of a design study and a subscale model wind tunnel test effort conducted to define an acoustically treated ejector shroud exhaust system for supersonic transport application is described. Coannular, 20-chute, and ejector shroud exhaust systems were evaluated. Program results were used in a mission analysis study to determine aircraft takeoff gross weight to perform a nominal design mission, under Federal Aviation Regulation (1969), Part 36, Stage 3 noise constraints. Mission trade study results confirmed that the ejector shroud was the best of the three exhaust systems studied with a significant takeoff gross weight advantage over the 20-chute suppressor nozzle which was the second best
Occupation and three-year incidence of respiratory symptoms and lung function decline: the ARIC Study
<p>Abstract</p> <p>Background</p> <p>Specific occupations are associated with adverse respiratory health. Inhalation exposures encountered in these jobs may place workers at risk of new-onset respiratory disease.</p> <p>Methods</p> <p>We analyzed data from 8,967 participants from the Atherosclerosis Risk in Communities (ARIC) study, a longitudinal cohort study. Participants included in this analysis were free of chronic cough and phlegm, wheezing, asthma, chronic bronchitis, emphysema, and other chronic lung conditions at the baseline examination, when they were aged 45-64 years. Using data collected in the baseline and first follow-up examination, we evaluated associations between occupation and the three-year incidence of cough, phlegm, wheezing, and airway obstruction and changes in forced expiratory volume in one second (FEV<sub>1</sub>) and forced vital capacity (FVC) measured by spirometry. All associations were adjusted for age, cigarettes per day, race, smoking status, and study center.</p> <p>Results</p> <p>During the approximately three-year follow-up, the percentage of participants developing chronic cough was 3%; chronic phlegm, 3%; wheezing, 3%; and airway obstruction, defined as FEV<sub>1 </sub>< lower limit of normal (LLN) and FEV<sub>1</sub>/FVC < LLN, 2%. The average annual declines in FEV<sub>1 </sub>and FVC were 56 mL and 66 mL, respectively, among men and 40 mL and 52 mL, respectively, among women. Relative to a referent category of managerial and administrative support occupations, elevated risks of new-onset chronic cough and chronic phlegm were observed for mechanics and repairers (chronic cough: RR: 1.81, 95% CI: 1.02, 3.21; chronic phlegm: RR: 2.10, 95% CI: 1.23, 3.57) and cleaning and building service workers (chronic cough: RR: 1.85, 95% CI: 1.01, 3.37; chronic phlegm: RR: 2.28, 95% CI: 1.27, 4.08). Despite the elevated risk of new-onset symptoms, employment in cleaning and building services was associated with attenuated lung function decline, particularly among men, who averaged annual declines in FEV<sub>1 </sub>and FVC of 14 mL and 23 mL, respectively, less than the declines observed in the referent population.</p> <p>Conclusions</p> <p>Employment in mechanic and repair jobs and cleaning and building service occupations are associated with increased incidence of respiratory symptoms. Specific occupations affect the respiratory health of adults without pre-existing respiratory health symptoms and conditions, though long-term health consequences of inhalation exposures in these jobs remain largely unexplored.</p
Hallmarks of Furman\u27s 2011 retirees: Commitment, foresight and integrity
At the close of the 2010-11 academic year, Furman said farewell to five faculty members who worked at the university for a combined 173 years. As a tribute to the retirees, all of whom have been awarded emeritus status, Furman magazine asked departmental colleagues (and, in two cases, former students) to comment on their careers and contributions
Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study.
ObjectiveWe aimed to identify factors that are independently associated with the metabolic clearance rate of insulin (MCRI) and to examine the association of MCRI with incident type 2 diabetes in nondiabetic Hispanics and African Americans.Research design and methodsWe investigated 1,116 participants in the Insulin Resistance Atherosclerosis Study (IRAS) Family Study with baseline examinations from 2000 to 2002 and follow-up examinations from 2005 to 2006. Insulin sensitivity (S(I)), acute insulin response (AIR), and MCRI were determined at baseline from frequently sampled intravenous glucose tolerance tests. MCRI was calculated as the ratio of the insulin dose over the incremental area under the curve of insulin. Incident diabetes was defined as fasting glucose ≥126 mg/dL or antidiabetic medication use by self-report.ResultsWe observed that S(I) and HDL cholesterol were independent positive correlates of MCRI, whereas fasting insulin, fasting glucose, subcutaneous adipose tissue, visceral adipose tissue, and AIR were independent negative correlates (all P < 0.05) at baseline. After 5 years of follow-up, 71 (6.4%) participants developed type 2 diabetes. Lower MCRI was associated with a higher risk of incident diabetes after adjusting for demographics, lifestyle factors, HDL cholesterol, indexes of obesity and adiposity, and insulin secretion (odds ratio 2.01 [95% CI 1.30-3.10], P = 0.0064, per one-SD decrease in loge-transformed MCRI).ConclusionsOur data showed that lower MCRI predicts the incidence of type 2 diabetes
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