395 research outputs found

    Relation of n-value to critical current in bent-damaged Bi2223 composite tape

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    AbstractThe relation of n-value to critical current of bent-damaged (Bi,Pb)2Sr2Ca2Cu3O10+δ (Bi2223) composite tape was studied experimentally and analytically. The experimental results showed that, under bending strain, the n-value decreased rather slightly with decreasing critical current in comparison with the data obtained under applied tensile strain. The experimentally observed slight decrease in n-value with critical current under bending strain, and the measured changes in critical current and n-value with increasing bending strain, were described satisfactorily by the presented damage evolution model that correlates the extent of damage to variation of bending strain-induced tensile strain in the core along the thickness direction

    Enhancement of peroxyoxalate chemiluminescence intensity by surfactants and its application to detect detergent.

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    Enhancement of peroxyoxalate chemiluminescence (PO-CL) intensity by a surfactant in the H(2)O(2)/bis(2,4,6-trichlorophenyl)oxalate (TCPO)/rhodamine B system was described. The effects of 15 surfactants were evaluated by comparing the ratio of a relative CL intensity (RCI) with surfactant to that of the blank in each system. In preliminary study, H(2)O(2)/imidazole-HNO(3) buffer/TCPO/rhodamine B system was used to study the effects of surfactants on PO-CL intensity. Fourteen surfactants reduced the CL intensity at the 2% concentration, where their relative CL intensities ranged from 0.6 to 93.5%. Some of these phenomena may be caused by a notable change of pH that was occurred by adding the surfactant. Additionally, enhancement of PO-CL intensity was studied by using system (1) H(2)O(2)/TCPO/rhodamine B and (2) H(2)O(2)/imidazole-HNO(3) buffer/TCPO/systems. In the system 1, the favorable enhancement of CL intensity (ranged from 124 to 472%) was observed with 9 surfactants at the 0.5% concentration. This result suggested that several surfactants might play a role as a catalyst in the PO-CL reaction. There was no tendency to enhance CL intensity among the surfactant types. In the system 2, the enhancement of CL intensity was also observed by adding with 11 surfactants, which might be mainly caused by the fluorescent impurities of surfactants used. Furthermore, detection of detergent commercially available was applied by using the system 1

    Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling.

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    Cellular signaling processes can exhibit pronounced cell-to-cell variability in genetically identical cells. This affects how individual cells respond differentially to the same environmental stimulus. However, the origins of cell-to-cell variability in cellular signaling systems remain poorly understood. Here, we measure the dynamics of phosphorylated MEK and ERK across cell populations and quantify the levels of population heterogeneity over time using high-throughput image cytometry. We use a statistical modeling framework to show that extrinsic noise, particularly that from upstream MEK, is the dominant factor causing cell-to-cell variability in ERK phosphorylation, rather than stochasticity in the phosphorylation/dephosphorylation of ERK. We furthermore show that without extrinsic noise in the core module, variable (including noisy) signals would be faithfully reproduced downstream, but the within-module extrinsic variability distorts these signals and leads to a drastic reduction in the mutual information between incoming signal and ERK activity
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