16 research outputs found
Muse, 1970-03-06
No full textMemorial University of Newfoundland's student newspaper, providing coverage of university life as well as national and international news relating to students.Frequency: biweekly, 1951-present. Not published: March 1954? - April 1955. Includes advertisements
Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance
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Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis
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In vivo CD8+ T Cell Dynamics in the Liver of Plasmodium yoelii Immunized and Infected Mice
No full textThe emerging role of ADAM metalloproteinases in immunity
No full textProteolysis is an irreversible physiological process that can result in the termination or activation of protein function. Many transmembrane proteins that are involved in the cellular communication between immune cells and structural cells-for example, Notch, CD23, CD44, and membrane-anchored cytokines and their receptors-are cleaved by the ADAM (a disintegrin and metalloproteinase) family of enzymes. Here, we review recent insights into the molecular activation, substrate specificity and function of ADAM proteins in the development and regulation of the immune system, with a particular focus on the roles of ADAM10 and ADAM17
