Dramaturgical Aspects of Professional Wrestling Matches

Paper

Risk-Based Decision Model for Determining the Applicability of an Earned Value Management System in Construction

New policy mandated by the Undersecretary of Defense for Acquisition, Technology and Logistics has lowered the dollar thresholds of contracts requiring earned value management (EVM). This policy directed that a risk-based decision be made to determine if EVM should be used on firm-fixed price contracts under $20 million. Although not previously applicable to Military Construction (MILCON) building projects or other Air Force Civil Engineer (CE) managed contracts, the new threshold requires that CE projects be evaluated for risk. Therefore, the focus of this research was to analyze the risk factors associated with construction contracts in an attempt to build a decision model to determine if EVM is warranted on the project. Due to the cost of implementing EVM, this model should probably be used only on Air Force construction projects with cost estimates over$5 million. If the cost growth predicted by the model is greater than 5%, the use of EVM is recommended to monitor the risk factors. However, this recommendation should be tempered with the overall risk associated with a given project. In other words, if the calculated cost growth is high but the probability of occurrence is low, the decision-maker may want to forego the use of EVM and the associated costs. The questions addressed by this research are as follows: (1) What risk factors affect the cost or schedule of Air Force construction projects?; (2) What is the probability of occurrence of the identified risk factors?; (3) What is the subsequent cost growth due to the occurrence of the risk factors?; and (4) How many Air Force construction projects accomplished in the last 5 years and those programmed through FY12 exceed the $20M threshold or fall into a range that must be evaluated

Enhancing governance of energy and water interdependencies

Policy note based on 3 policy and industry workshops in 2014 and 2015

Unveiling the security concerns of low carbon development:climate security analysis of the undesirable and unintended effects of mitigation and adaptation

In debates of climate action, low carbon development has been widely advocated as an opportunity arising from climate change. This paper problematizes low carbon development, arguing that there are undesirable, unintended or perverse effects that give rise to distinct and serious security concerns. The literature on climate security has addressed the effects of climate threats on conflict but there is a notable paucity of research analysing the security implications of responses to climate change in the form of low carbon development. The paper presents critical analysis of the ways low carbon development yields new security concerns as well as entrenching existing ones. Five dimensions of security are examined: spatially uneven effects of low carbon development; violent imaginaries of the global south and the production of ‘ungoverned spaces’; non-violent yet harmful instances of conflict; marginalization and dispossession; depoliticized, techno-managerial effects of resilience. The paper shows that climate (in)security manifests in variegated ways between different populations and spatial scales. Consequently, how, when for whom low carbon development becomes a threat or opportunity is socially constructed and deeply political

Unified Chew-Mandelstam SAID analysis of pion photoproduction data

A unified description of single-pion photoproduction data, together with pion- and eta-hadroproduction data, has been achieved in a Chew-Mandelstam parametrization which is consistent with unitarity at the two-body level. Energy-dependent and single-energy partial wave analyses of pion photoproduction data have been performed and compared to previous SAID fits and multipoles from the Mainz and Bonn-Gatchina groups.Comment: 11 pages, 9 figures, and 2 table

Co-crystalization and in vitro biological characterization of 5-Aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors

A potential therapeutic strategy for targeting cancer that has gained much interest is the inhibition of the ATP binding and ATPase activity of the molecular chaperone Hsp90. We have determined the structure of the human Hsp90α N-terminal domain in complex with a series of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazoles. The structures provide the molecular details for the activity of these inhibitors. One of these inhibitors, ICPD 34, causes a structural change that affects a mobile loop, which adopts a conformation similar to that seen in complexes with ADP, rather than the conformation generally seen with the pyrazole/isoxazole-resorcinol class of inhibitors. Competitive binding to the Hsp90 N-terminal domain was observed in a biochemical assay, and these compounds showed antiproliferative activity and induced apoptosis in the HCT116 human colon cancer cell line. These inhibitors also caused induction of the heat shock response with the upregulation of Hsp72 and Hsp27 protein expression and the depletion of Hsp90 clients, CRAF, ERBB2 and CDK4, thus confirming that antiproliferative activity was through the inhibition of Hsp90. The presence of increased levels of the cleavage product of PARP indicated apoptosis in response to Hsp90 inhibitors. This work provides a framework for the further optimization of thiadiazole inhibitors of Hsp90. Importantly, we demonstrate that the thiadiazole inhibitors display a more limited core set of interactions relative to the clinical trial candidate NVP-AUY922, and consequently may be less susceptible to resistance derived through mutations in Hsp9

Decision making for net zero policy design and climate action:Considerations for improving translation at the research-policy interface: A UK Carbon Dioxide Removal Case Study

The impacts of climate change on society and the natural environment are being experienced now, with extreme weather events increasing in frequency and severity across the globe. To keep the Paris Agreement's ambition of limiting warming to 1.5ºC above pre-industrial levels there is now also a need to establish and scale a new sector to remove CO2 at Giga-tonne scale for over a century. Despite this mounting evidence and warnings, current climate policy in the UK and globally falls far short of achieving the required reductions in CO2 emissions or establishment of a new removal sector needed to stave off the risks posed by climate change. Some of the science on climate risk is abundant and well evidenced, but the policy response is lacking in effectiveness. Other evidence to design policy, such as Carbon Dioxide Removal (CDR), is fraught with deep uncertainty. Why are the plethora of scientific evidence, assessments and decision support tools available to decision and policymakers not always translating into effective climate-net zero policy action? How can emergent evidence be brought in introduced to shape new sectors such as CDR? What are the capacity gaps? Through a combination of literature review, interviews and UK policy workshops over 17 months these are some of the questions that this contribution sought insight. We set out three recommendations for policymakers and other stakeholders, including academic researchers and third sector organisations, to address the identified gaps associated with translating climate risk and net zero decision support into effective climate policy: Enhance collaboration between decision-makers, policymakers, analysts, researchers, and other stakeholders to co-develop and co-design operational climate risk assessments and policies, relevant to context. Identify the research and capacity gaps around climate risk decision-making under uncertainty, and work with stakeholders across the decision value chain to ensure those gaps are addressed. Co-create effective translation mechanisms to embed decision-support tools into policy better, employing a participatory approach to ensure inclusion of diverse values and viewpoints. It is fundamental that there is improvement in our understanding about how we can make good decisions and operationalise them, rather than simply focus on further research on the climate risk and net zero problem

Decision making for net zero policy design and climate action:Considerations for improving translation at the research-policy interface: A UK Carbon Dioxide Removal Case Study

The impacts of climate change on society and the natural environment are being experienced now, with extreme weather events increasing in frequency and severity across the globe. To keep the Paris Agreement's ambition of limiting warming to 1.5ºC above pre-industrial levels there is now also a need to establish and scale a new sector to remove CO2 at Giga-tonne scale for over a century. Despite this mounting evidence and warnings, current climate policy in the UK and globally falls far short of achieving the required reductions in CO2 emissions or establishment of a new removal sector needed to stave off the risks posed by climate change. Some of the science on climate risk is abundant and well evidenced, but the policy response is lacking in effectiveness. Other evidence to design policy, such as Carbon Dioxide Removal (CDR), is fraught with deep uncertainty. Why are the plethora of scientific evidence, assessments and decision support tools available to decision and policymakers not always translating into effective climate-net zero policy action? How can emergent evidence be brought in introduced to shape new sectors such as CDR? What are the capacity gaps? Through a combination of literature review, interviews and UK policy workshops over 17 months these are some of the questions that this contribution sought insight. We set out three recommendations for policymakers and other stakeholders, including academic researchers and third sector organisations, to address the identified gaps associated with translating climate risk and net zero decision support into effective climate policy: Enhance collaboration between decision-makers, policymakers, analysts, researchers, and other stakeholders to co-develop and co-design operational climate risk assessments and policies, relevant to context. Identify the research and capacity gaps around climate risk decision-making under uncertainty, and work with stakeholders across the decision value chain to ensure those gaps are addressed. Co-create effective translation mechanisms to embed decision-support tools into policy better, employing a participatory approach to ensure inclusion of diverse values and viewpoints. It is fundamental that there is improvement in our understanding about how we can make good decisions and operationalise them, rather than simply focus on further research on the climate risk and net zero problem

Hydrologic Properties of Pervious Concrete

Pervious concrete is concrete made by eliminating most or all of the fine aggregate (sand) in the concrete mix, which allows interconnected void spaces to be formed in the hardened product. These interconnected void spaces allow the concrete to transmit water at relatively high rates. The main objective of this project was to conduct research on the potential application of pervious concrete in agricultural settings, specifically for use in animal feed lots, manure storage pads, animal manure and bedding compost facilities, or floor systems in animal buildings. Laboratory tests were conducted on replicated samples of pervious concrete formed from two rock sources (river gravel and limestone) for coarse aggregates and different size fractions to determine hydrologic relationships. Linear relationships were found between density and porosity, density and permeability, porosity and permeability, and porosity and specific yield. The results suggest that properties such as permeability, porosity, and specific yield are not significantly affected by different aggregate types. However, density and porosity can be effective methods for predicting porosity, specific yield, and permeability. In addition, t-tests were conducted to determine the effect of aggregate types on the solid/liquid separation properties of the pervious concrete after adding composted beef cattle manure and bedding to the surface of the specimens. The amount of composted beef cattle manure and bedding retained within the specimens was significantly less (p = 0.012) when samples constructed of #8 river gravel were used rather than the other aggregates. The #8 river gravel also had significantly less reduction in permeability compared to other aggregates. Although the #8 river gravel had a different effect on the compost retained and the reduction in permeability for the specimens, all four aggregates exhibited a significant reduction in the permeability after the compost was applied