809 research outputs found

    Cost-minimizing preemptive scheduling of mapreduce workloads on hybrid clouds

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    MapReduce has become the dominant programming model for processing massive amounts of data on cloud platforms. More and more enterprises are now utilizing hybrid clouds, consisting of private infrastructure owned by themselves and public clouds such as Amazon EC2, to process their spiky MapReduce workloads, which fully utilize their own on-premise resources while outsourcing the tasks only when needed. With disparate workloads of different MapReduce tasks, an efficient scheduling mechanism is in need to enable efficient utilization of the on-premise resources and to minimize the task outsourcing cost, while meeting the task completion time requirements as well. In this paper, a fine-grained model is described to characterize the scheduling of heterogeneous MapReduce workloads, and an online algorithm is proposed for joint task admission control into the private cloud, task outsourcing to the public cloud, and VM allocation to execute the admitted tasks on the private cloud, such that the time-averaged task outsourcing cost is minimized over the long run. The online algorithm features preemptive scheduling of the tasks, where a task executed partially on the on-premise infrastructure can be paused and scheduled to run later. It also achieves desirable properties such as meeting a pre-set task admission ratio and bounding the worst-case task completion time, as proven by our rigorous theoretical analysis. © 2013 IEEE.published_or_final_versio

    Design and analysis of a flux-controllable linear variable reluctance machine

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    Design and analysis of a new magnetic gear with multiple gear ratios

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    Robust optimization in HTS cable based on DEPSO and design for six sigma

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    The non-uniform AC current distribution among the multi-layer conductors in a high-temperature superconducting (HTS) cable reduces the current capacity and increases the AC loss. In this paper, Particle swarm optimization coupled with differential evolution operator (DEPSO) has been applied in structural optimization of HTS cables. While the existence of fluctuation in design variables or operation conditions has a great influence on the cable quality, in order to eliminate the effects of parameter perturbations in design and improve the design efficiency, a robust design method based on design for six sigma (DFSS) is applied in this paper. The optimization solutions show that the proposed optimization procedure can not only achieve a uniform current distribution, but also improve significantly the reliability and robustness of the HTS cable quality. © 2008 IEEE

    Wireless power transfer and fault diagnosis of high-voltage power line via robotic bird

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    Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice

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    Aim To explore the roles of C-X-C chemokine receptor type 4 (CXCR4) in spinal processing of neuropathic pain at the central nervous system (CNS). Methods Peripheral neuropathic pain (PNP) induced by partial sciatic nerve ligation (pSNL) model was assessed in mice. Effects of a single intrathecal (central) administration of AMD3100 (intrathecal AMD3100), a CXCR4 antagonist, on pain behavior and pain-related spinal pathways and molecules in the L3-L5 spinal cord segment was studied compare to saline treatment. Results Rotarod test showed that intrathecal AMD3100 did not impair mice motor function. In pSNL-induced mice, intrathecal AMD3100 delayed the development of mechanical allodynia and reversed the established mechanical allodynia in a dose-dependent way. Moreover, intrathecal AMD3100 downregulated the activation of JNK1 and p38 pathways and the protein expression of p65 as assessed by western blotting. Real-time PCR test also demonstrated that substance P mRNA was decreased, while adrenomedullin and intercellular adhesion molecule mRNA was increased following AMD3100 treatment. Conclusion Our results suggest that central (spinal) CXCR4 is involved in the development and maintenance of PNP and the regulation of multiple spinal molecular events under pain condition, implicating that CXCR4 would potentially be a therapeutic target for chronic neuropathic pain.published_or_final_versio

    Inhibition Of Spinal Endothelin Type A Receptor Ameliorates Neuropathic Pain Through Down-regulation Of Mapk And Nf--κappab P65 In Rats

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    Conference Theme: Translating Evidence into PracticeLate-Breaking Poster Session 3: abstract no. EFIC5-1288 / Poster board no. 508published_or_final_versio
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