There are Real People in There? Blogging at the University of Worcester.

Communication has long been one of the major issues facing us in the library profession. Communication with our users, with our wider organisation and even amongst ourselves had been highlighted at the University of Worcester as an area in need of vast improvement, and in 2004 we took our first tentative steps into the Web 2.0 world as a potential method for providing the library with a much needed presence. This paper aims to demonstrate our evolution from static web pages, delivering half-hearted and wildly sporadic attempts at news, to an institution fronted by an actual human voice. I’ll aim to show that Web 2.0 is ironically not about technology, but about the style of communication it encourages, and how we’ve been able to use these applications to return to some of the traditional values of librarianship in a truly modern, relevant way

Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations.

"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population. Quantile-specific offspring-parent regression slopes (βOP) were estimated by quantile regression for 6227 offspring-parent pairs. Quantile-specific heritability (h2), estimated by 2βOP/(1 + rspouse), decreased 0.0047 ± 0.0007 (P = 2.9 × 10-14) for each one-percent decrement in fasting triglyceride concentrations, i.e., h2 ± SE were: 0.428 ± 0.059, 0.230 ± 0.030, 0.111 ± 0.015, 0.050 ± 0.016, and 0.033 ± 0.010 at the 90th, 75th, 50th, 25th, and 10th percentiles of the triglyceride distribution, respectively. Consistent with quantile-dependent expressivity, 11 drug studies report smaller genotype differences at lower (post-treatment) than higher (pre-treatment) triglyceride concentrations. This meant genotype-specific triglyceride changes could not move in parallel when triglycerides were decreased pharmacologically, so that subtracting pre-treatment from post-treatment triglyceride levels necessarily created a greater triglyceride decrease for the genotype with a higher pre-treatment value (purported precision-medicine genetic markers). In addition, sixty-five purported gene-environment interactions were found to be potentially attributable to triglyceride's quantile-dependent expressivity, including gene-adiposity (APOA5, APOB, APOE, GCKR, IRS-1, LPL, MTHFR, PCSK9, PNPLA3, PPARγ2), gene-exercise (APOA1, APOA2, LPL), gene-diet (APOA5, APOE, INSIG2, LPL, MYB, NXPH1, PER2, TNFA), gene-alcohol (ALDH2, APOA5, APOC3, CETP, LPL), gene-smoking (APOC3, CYBA, LPL, USF1), gene-pregnancy (LPL), and gene-insulin resistance interactions (APOE, LPL)

Creating a new town koine : children and language change in Milton Keynes.

Koineization – the development of a new, mixed variety following dialect contact – has well-documented outcomes. However, there have been few studies of the phenomenon actually in progress. This article describes the development of a new variety in the English New Town of Milton Keynes, designated in 1967. The article is structured around eight “principles” that relate the process of koineization to its outcomes. Recordings were made of 48 Milton Keynes-born children in three age groups (4, 8, and 12), the principal caregiver of each child, and several elderly locally born residents. Quantitative analysis of ten phonetic variables suggests that substantial but not complete focusing occurs in the child generation. The lack of linguistic continuity in the New Town is demonstrated, and the time scale of koineization there is discussed. Finally, it is shown that demography and the social-network characteristics of individuals are crucial to the outcomes of koineization

Environmental Cross Compliance - Panacea or Placebo?

Environmental Cross Compliance is one policy by means by which government can seek to influence farmers so that they give greater weight to environmental goods in their decisions. The policy is evaluated from both a theoretical and pragmatic viewpoint and its strengths and weaknesses are discussed. The necessary conditions for the success of environmental cross compliance policies are identified and problems with its implementation are highlighted.Environmental Economics and Policy, Farm Management,

Simulating emotional reactions in medical dramas

Presenting information on emotionally charged topics is a delicate task: if bare facts alone are conveyed, there is a risk of boring the audience, or coming across as cold and unfeeling; on the other hand, emotional presentation can be appropriate when carefully handled, but when overdone or mishandled risks being perceived as patronising or in poor taste. When Natural Language Generation (NLG) systems present emotionally charged information linguistically, by generating scripts for embodied agents, emotional/affective aspects cannot be ignored. It is important to ensure that viewers consider the presentation appropriate and sympathetic. We are investigating the role of affect in communicating medical information in the context of an NLG system that generates short medical dramas enacted by embodied agents. The dramas have both an informational and an educational purpose in that they help patients review their medical histories whilst receiving explanations of less familiar medical terms and demonstrations of their usage. The dramas are also personalised since they are generated from the patients' own medical records. We view generation of natural/appropriate emotional language as a way to engage and maintain the viewers' attention. For our medical setting, we hypothesize that viewers will consider dialogues more natural when they have an enthusiastic and sympathetic emotional tone. Our second hypothesis proposes that such dialogues are also better for engaging the viewers' attention. As well as describing our NLG system for generating natural emotional language in medical dialogue, we present a pilot study with which we investigate our two hypotheses. Our results were not quite as unequivocal as we had hoped. Firstly, our participants did notice whether a character sympathised with the patient and was enthusiastic. This did not, however, lead them to judge such a character as behaving more naturally or the dialogue as being more engaging. However, when pooling data from our two conditions, dialogues with versus dialogues without emotionally appropriate language use, we discovered, somewhat surprisingly, that participants did consider a dialogue more engaging if they believed that the characters showed sympathy towards the patient, were not cold and unfeeling, and were natural (true for the female agent only)