Next-generation sequencing: applications beyond genomes.

The development of DNA sequencing more than 30 years ago has profoundly impacted biological research. In the last couple of years, remarkable technological innovations have emerged that allow the direct and cost-effective sequencing of complex samples at unprecedented scale and speed. These next-generation technologies make it feasible to sequence not only static genomes, but also entire transcriptomes expressed under different conditions. These and other powerful applications of next-generation sequencing are rapidly revolutionizing the way genomic studies are carried out. Below, we provide a snapshot of these exciting new approaches to understanding the properties and functions of genomes. Given that sequencing-based assays may increasingly supersede microarray-based assays, we also compare and contrast data obtained from these distinct approaches

Z-stability and finite dimensional tracial boundaries

We show that a simple separable unital nuclear nonelementary C∗-algebra whose tracial state space has a compact extreme boundary with finite covering dimension admits uniformly tracially large order zero maps from matrix algebras into its central sequence algebra. As a consequence, strict comparison implies Z-stability for these algebras

Pesticide Use on Fruit and Vegetable Crops in Ohio 1990

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