Retinolemia em escolares eutróficos e com sobrepeso

Objectives: To determine the frequency of normal weight and overweight schoolchildren who have deficiency of vitamin A and to study the relationship between serum retinol concentrations and body mass index (BMI), body fat percentage and waist circumference of normal weight and overweight children. Methods: Cross-sectional, descriptive and analytical study carried out with schoolchildren aged 8 to 10 years old from public schools in Uberaba (MG). The sample consisted of eighty students matched for age and sex, being forty eutrophic schoolchildren and forty with overweight. Results: It was observed that 25% of students were overweight and 20% of normal weight children presented serum retinol disabled. There was no significant difference between the mean serum retinol concentrations in the eutrophic schoolchildren group and overweight group. No significant correlations were observed between serum concentrations and BMI, waist circumference and body fat percentage measured by bioelectrical impedance in both groups. Conclusion: The results show a high prevalence of deficient serum retinol, which are not related to body fat percentage and waist circumference measurement, in two groups of healthy schoolchildren, an eutrophic and another group, overweight

MANAGERS’ PERCEPTIONS ABOUT THE CONTRIBUTIONS OF THE ISO 14001 CERTIFICATION PROCESS TO ENVIRONMENTAL ACCOUNTING PRACTICES

A necessidade de harmonizar o desenvolvimento econômico com a proteção ambiental fez surgir o que se convencionou chamar de desenvolvimento e sustentabilidade. Este estudo objetiva conhecer a percepção de gestores sobre o processo de certificação ISO 14001 nas práticas de gestão do meio ambiente em uma indústria Sucroalcooleira do estado de Minas Gerais. Tratou-se de uma pesquisa descritiva de abordagem qualitativa. Os dados foram coletados por meio de entrevista e da análise documental. Constatou-se haver integração entre o processo de certificação, o sistema de gestão ambiental (SGA) e as outras áreas, fatos que proporcionam uma eficácia das práticas de gestão do meio ambiente. O processo de certificação ambiental beneficia-se da implementação do SGA, tendo em vista a melhoria do desempenho ambiental e, assim, de outros aspectos como a imagem da empresa e agregação de valor ao produto. Conclui-se que a atuação integrada da equipe gestora, de certificação ambiental e demais áreas conduzem a um melhor desempenho ambiental contribuindo assim para o alinhamento entre a gestão, as metas e as estratégias organizacionais.The need to harmonize economic development with environmental protection gave rise to what is usually called development and sustainability. This study is aimed at getting to know managers’ perception about the ISO 14001 certification process in environmental management practices in a sugar and alcohol industry in the State of Minas Gerais, Brazil. A descriptive research with a qualitative approach was undertaken. Data were collected through interviews and documentary analysis. The certification process is integrated in the environmental management system and the other fact areas enhance the effectiveness of environmental management practices. The environmental certification process benefits from the implementation of an environmental management system, with a view to improving environmental performance and, consequently, other aspects like company image and the value added to the product. In conclusion, the integrated action of the management team, environmental certification and other areas leads to a better environmental performance, thus contributing to the alignment among management, targets and organizational strategies

Pedagogia crítica e direitos humanos: fundamentos para uma proposta pedagógico-crítica em direitos humanos

Este artigo reflete sobre a necessidade de encontrar uma teoria pedagógica que ofereça sustentação à ação educativa em Direitos Humanos, apresentando uma proposta pedagógico-crítica alicerçada nos pressupostos da teoria e da pedagogia críticas, privilegiando a pedagogia freireana, numa perspectiva atualizada para os Direitos Humanos. Nesse sentido, o trabalho tem o propósito de discutir um fundamento teórico-crítico para a Educação em Direitos Humanos, buscando novas formas de investigação e de análise para sua compreensão, apropriando-se de conceitos críticos como conscientização, autonomia, diálogo e emancipação. Finalmente, considera que uma prática pedagógica crítica em Direitos Humanos contribui para a leitura do mundo do excluído, para sua inclusão na sociedade e para a compreensão de que é possível desconstruir relações e práticas sociais injustas.(undefined

Demostración de resultado económico: percepción del comando da aeronáutica de Brasil

No ano de 2010, uma alteração no quadro normativo brasileiro introduziu a Demonstração do Resultado Econômico (DRE) para o setor público, que busca comparar custos internos de produção com valores de mercado, segundo o conceito de custo de oportunidade. Este estudo procura analisar as possíveis respostas estratégicas dos gestores , buscando perceber se a cultura contábil existente no País permite a aceitação do novo instrumento. Por meio das percepções dos agentes públicos do Comando da Aeronáutica (Comaer), no Brasil, conclui-se que a resposta estratégica dos entrevistados tende para a atitude de aceitação da nova rotina, demonstrando traços de menor conservadorismo e maior interesse pela evidenciação de resultados.In 2010, a change in the Brazilian accounting regulatory framework introduced the Demonstração do Resultado Econômico (DRE) [Economic Income Statement] for the public sector, which seeks to compare the internal costs of production to market values, according to the concept of opportunity cost. This study aims to analyse the possible strategic responses of managers and tries to understand if the existing accounting culture in Brazil facilitates the introduction of the new statement. By means of perceptions of officials of the Aeronautical Command (Comaer), in Brazil, it is possible to conclude that the strategic response of respondents is closer to acceptance of the new routine, showing traces of less conservatism and greater interest for displaying results.En el año 2010, una modificación del cuadro normativo brasileño introdujo la Demostración del Resultado Económico (DRE) para el sector público, que busca comparar los costos internos de producción con los valores del mercado, según el concepto de costo de oportunidad. Este estudio tiene como objetivo analizar las posibles respuestas estratégicas de los gestores, con el fin de percibir si la cultura contable existente en el país permite la aceptación del nuevo instrumento. Por medio de las percepciones de los agentes públicos del Comando da Aeronáutica (Comaer), en Brasil, se concluyó que la respuesta estratégica de los entrevistados tiende a aceptar la nueva rutina, mostrando rasgos de menos conservadurismo y más interés por la manifestación de resultados.Fundação para a Ciência e a Tecnologia (FCT

Dengue-2 Structural Proteins Associate with Human Proteins to Produce a Coagulation and Innate Immune Response Biased Interactome

<p>Abstract</p> <p>Background</p> <p>Dengue virus infection is a public health threat to hundreds of millions of individuals in the tropical regions of the globe. Although Dengue infection usually manifests itself in its mildest, though often debilitating clinical form, dengue fever, life-threatening complications commonly arise in the form of hemorrhagic shock and encephalitis. The etiological basis for the virus-induced pathology in general, and the different clinical manifestations in particular, are not well understood. We reasoned that a detailed knowledge of the global biological processes affected by virus entry into a cell might help shed new light on this long-standing problem.</p> <p>Methods</p> <p>A bacterial two-hybrid screen using DENV2 structural proteins as bait was performed, and the results were used to feed a manually curated, global dengue-human protein interaction network. Gene ontology and pathway enrichment, along with network topology and microarray meta-analysis, were used to generate hypothesis regarding dengue disease biology.</p> <p>Results</p> <p>Combining bioinformatic tools with two-hybrid technology, we screened human cDNA libraries to catalogue proteins physically interacting with the DENV2 virus structural proteins, Env, cap and PrM. We identified 31 interacting human proteins representing distinct biological processes that are closely related to the major clinical diagnostic feature of dengue infection: haemostatic imbalance. In addition, we found dengue-binding human proteins involved with additional key aspects, previously described as fundamental for virus entry into cells and the innate immune response to infection. Construction of a DENV2-human global protein interaction network revealed interesting biological properties suggested by simple network topology analysis.</p> <p>Conclusions</p> <p>Our experimental strategy revealed that dengue structural proteins interact with human protein targets involved in the maintenance of blood coagulation and innate anti-viral response processes, and predicts that the interaction of dengue proteins with a proposed human protein interaction network produces a modified biological outcome that may be behind the hallmark pathologies of dengue infection.</p