31 research outputs found
Wnt signalling and cancer stem cells
Get PDF[Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and stem cell function in adult tissues. Aberrant activation of Wnt signalling pathways has been directly linked to the genesis of different tumours. Here, the components and molecular mechanisms implicated in the transduction of Wnt signal, along with important results supporting a central role for this signalling pathway in stem cell function regulation and carcinogenesis will be briefly reviewed.Ministerio de Ciencia e InnovaciĂłn; SAF2008-0060
Hipervitaminose D em animais
Full text linkPor meio de revisĂŁo da literatura, sĂŁo apresentados dados referentes ao metabolismo da vitamina D, bem como aos principais aspectos toxicolĂłgicos, clĂnicos, bioquĂmicos, macroscĂłpicos, microscĂłpicos, ultraestruturais, imuno-histoquĂmicos e radiográficos de animais intoxicados natural e experimentalmente por essa vitamina, em diferentes espĂ©cies. Este estudo objetiva demonstrar a existĂŞncia de muitas lacunas no conhecimento sobre mineralização fisiolĂłgica e patolĂłgica, em especial na mediação hormonal do fenĂ´meno, bem como alertar para os riscos de ocorrĂŞncia dessa intoxicação
The interaction of divalent cations, hormones and cyclic nucleotides in the control of mitosis
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Observations on the Pathogenesis of Silicosis by Means of the Diffusion Chamber Technique
No full textCarcinomas in papillary cystadenolymphomas of the parotid gland ? definition and differential diagnosis
No full textBovine Liver Chromatin Fraction Contains Actin Polymerization Activity Inducing Micronuclei Formation when Injected into Prometaphase Cultured Cells.
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