Wear of human teeth: a tribological perspective

The four main types of wear in teeth are attrition (enamel-on-enamel contact), abrasion (wear due to abrasive particles in food or toothpaste), abfraction (cracking in enamel and subsequent material loss), and erosion (chemical decomposition of the tooth). They occur as a result of a number of mechanisms including thegosis (sliding of teeth into their lateral position), bruxism (tooth grinding), mastication (chewing), toothbrushing, tooth flexure, and chemical effects. In this paper the current understanding of wear of enamel and dentine in teeth is reviewed in terms of these mechanisms and the major influencing factors are examined. In vitro tooth wear simulation and in vivo wear measurement and ranking are also discussed

Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain

Focused ultrasound and microbubbles can non-invasively and locally deliver therapeutics and imaging agents across the blood–brain barrier. Uniform treatment and minimal adverse bioeffects are critical to achieve reliable doses and enable safe routine use of this technique. Towards these aims, we have previously designed a rapid short-pulse ultrasound sequence and used it to deliver a 3 kDa model agent to mouse brains. We observed a homogeneous distribution in delivery and blood–brain barrier closing within 10 min. However, many therapeutics and imaging agents are larger than 3 kDa, such as antibody fragments and antisense oligonucleotides. Here, we evaluate the feasibility of using rapid short-pulses to deliver higher-molecular-weight model agents. 3, 10 and 70 kDa dextrans were successfully delivered to mouse brains, with decreasing doses and more heterogeneous distributions with increasing agent size. Minimal extravasation of endogenous albumin (66.5 kDa) was observed, while immunoglobulin (~ 150 kDa) and PEGylated liposomes (97.9 nm) were not detected. This study indicates that rapid short-pulses are versatile and, at an acoustic pressure of 0.35 MPa, can deliver therapeutics and imaging agents of sizes up to a hydrodynamic diameter between 8 nm (70 kDa dextran) and 11 nm (immunoglobulin). Increasing the acoustic pressure can extend the use of rapid short-pulses to deliver agents beyond this threshold, with little compromise on safety. This study demonstrates the potential for deliveries of higher-molecular-weight therapeutics and imaging agents using rapid short-pulses

Optical monitoring of the gravitationally lensed quasar Q2237+0305 from APO between June 1995 and January 1998

We present a data set of images of the gravitationally lensed quasar Q2237+0305, that was obtained at the Apache Point Observatory (APO) between June 1995 and January 1998. Although the images were taken under variable, often poor seeing conditions and with coarse pixel sampling, photometry is possible for the two brighter quasar images A and B with the help of exact quasar image positions from HST observations. We obtain a light curve with 73 data points for each of the images A and B. There is evidence for a long (>~ 100 day) brightness peak in image A in 1996 with an amplitude of about 0.4 to 0.5 mag (relative to 1995), which indicates that microlensing has been taking place in the lensing galaxy. Image B does not vary much over the course of the observation period. The long, smooth variation of the light curve is similar to the results from the OGLE monitoring of the system (Wozniak et al. 2000a).Comment: 8 pages, 5 figures; accepted for publication in A&

Discovery of an Unusual Dwarf Galaxy in the Outskirts of the Milky Way

In this Letter, we announce the discovery of a new dwarf galaxy, Leo T, in the Local Group. It was found as a stellar overdensity in the Sloan Digital Sky Survey Data Release 5 (SDSS DR5). The color-magnitude diagram of Leo T shows two well-defined features, which we interpret as a red giant branch and a sequence of young, massive stars. As judged from fits to the color-magnitude diagram, it lies at a distance of about 420 kpc and has an intermediate-age stellar population with a metallicity of [Fe/H]= -1.6, together with a young population of blue stars of age of 200 Myr. There is a compact cloud of neutral hydrogen with mass roughly 10^5 solar masses and radial velocity 35 km/s coincident with the object visible in the HIPASS channel maps. Leo T is the smallest, lowest luminosity galaxy found to date with recent star-formation. It appears to be a transition object similar to, but much lower luminosity than, the Phoenix dwarf.Comment: Ap J (Letters) in press, the subject of an SDSS press release toda

Exact soliton solution and inelastic two-soliton collision in spin chain driven by a time-dependent magnetic field

We investigate dynamics of exact N-soliton trains in spin chain driven by a time-dependent magnetic field by means of an inverse scattering transformation. The one-soliton solution indicates obviously the spin precession around the magnetic field and periodic shape-variation induced by the time varying field as well. In terms of the general soliton solutions N-soliton interaction and particularly various two-soliton collisions are analyzed. The inelastic collision by which we mean the soliton shape change before and after collision appears generally due to the time varying field. We, moreover, show that complete inelastic collisions can be achieved by adjusting spectrum and field parameters. This may lead a potential technique of shape control of soliton.Comment: 5 pages, 5 figure

A Close Binary Star Resolved from Occultation by 87 Sylvia

The star BD+29 1748 was resolved to be a close binary from its occultation by the asteroid 87 Sylvia on 2006 December 18 UT. Four telescopes were used to observe this event at two sites separated by some 80 km apart. Two flux drops were observed at one site, whereas only one flux drop was detected at the other. From the long-term variation of Sylvia, we inferred the probable shape of the shadow during the occultation, and this in turn constrains the binary parameters: the two components of BD+29 1748 have a projected separation of 0.097" to 0.110" on the sky with a position angle 104 deg to 107 deg. The asteroid was clearly resolved with a size scale ranging from 130 to 290 km, as projected onto the occultation direction. No occultation was detected for either of the two known moonlets of 87 Sylvia.Comment: 12 pages, 4 figures, 2 tables; submitted to the PAS

The Landau Pole and Z′Z^{\prime} decays in the 331 bilepton model

We calculate the decay widths and branching ratios of the extra neutral boson $Z^{\prime}$ predicted by the 331 bilepton model in the framework of two different particle contents. These calculations are performed taken into account oblique radiative corrections, and Flavor Changing Neutral Currents (FCNC) under the ansatz of Matsuda as a texture for the quark mass matrices. Contributions of the order of $10^{-1}-10^{-2}$ are obtained in the branching ratios, and partial widths about one order of magnitude bigger in relation with other non- and bilepton models are also obtained. A Landau-like pole arise at 3.5 TeV considering the full particle content of the minimal model (MM), where the exotic sector is considered as a degenerated spectrum at 3 TeV scale. The Landau pole problem can be avoid at the TeV scales if a new leptonic content running below the threshold at $$ TeV is implemented as suggested by other authors.Comment: 20 pages, 5 figures, LaTeX2

The system parameters of DW Ursae Majoris

We present new constraints on the system parameters of the SW Sextantis star DW Ursae Majoris, based on ultraviolet (UV) eclipse observations with the Hubble Space Telescope. Our data were obtained during a low state of the system, in which the UV light was dominated by the hot white dwarf (WD) primary. Eclipse analysis, using the full Roche lobe geometry, allows us to set firm limits on the masses and radii of the system components and the distance between them: 0.67 \leq M_1/M_sun \leq 1.06, 0.008 \leq R_1/R_sun \leq 0.014, M_2/M_sun > 0.16, R_2/R_sun > 0.28 and a/R_sun > 1.05. For q = M_2/M_1 < 1.5 the inclination must satisfy i > 71 degrees. Using Smith & Dhillon's mass-period relation for CV secondaries, our estimates for the system parameters become M_1/M_sun = 0.77 \pm 0.07, R_1/R_sun = 0.012 \pm 0.001, M_2/M_sun = 0.30 \pm 0.10, R_2/R_sun = 0.34 \pm 0.04, q =0.39 \pm 0.12, i = 82 \pm 4 degrees and a/R_sun = 1.14 \pm 0.06. We have also estimated the spectral type of the secondary, M3.5 \pm 1.0, and distance to the system, d =930 \pm 160 pc, from time-resolved I- and K-band photometry. Finally, we have repeated Knigge et al.'s WD model atmosphere fit to the low-state UV spectrum of DW UMa in order to account for the higher surface gravity indicated by our eclipse analysis. In this way we obtained a second estimate for the distance, d = 590 \pm 100 pc, which allows us to obtain a second estimate for the spectral type of the secondary, M7 \pm 2.0. We conclude that the true value for the distance and spectral type will probably be in between the values obtained by the two methods.Comment: 23 pages including 5 figures and 3 tables. Accepted for publication in Ap