4,867 research outputs found

    Differential Entropy on Statistical Spaces

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    We show that the previously introduced concept of distance on statistical spaces leads to a straightforward definition of differential entropy on these statistical spaces. These spaces are characterized by the fact that their points can only be localized within a certain volume and exhibit thus a feature of fuzziness. This implies that Riemann integrability of relevant integrals is no longer secured. Some discussion on the specialization of this formalism to quantum states concludes the paper.Comment: 4 pages, to appear in the proceedings of the joint meeting of the 2nd International Conference on Cybernetics and Information Technologies, Systems and Applications (CITSA 2005) and the 11th International Conference on Information Systems Analysis and Synthesis (ISAS 2005), to be held in Orlando, USA, on July 14-17, 200

    Francis F. Maury, M.D. (1840 to 1879): an often forgotten pioneer in early American surgery.

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    Francis F. Maury (Fig. 1) was born on August 9, 1840, in Danville, Kentucky, where he was raised on a farm by his mother and father. His father was an Episcopal clergyman of Huguenot descent, whose forefathers had fled from France to escape religious persecution. After receiving a Bachelor of Arts degree from Center College in the summer of 1860, he entered medical school at the University of Virginia. After one full term, he matriculated to Philadelphia’s Jefferson Medical College and completed his medical education as a private student under the direction of Dr. Samuel D. Gross.1, 2 He obtained his Doctorate of Medicine in March of 1862 at the age of only 21 years. Such were his talents as a medical student that he was appointed resident physician at the Philadelphia Hospital one month before his graduation. Although he spent only one year there, he developed a reputation as a tireless, devoted, and charming surgeon. In April 1863, Maury was assigned to duty at the South Street General Hospital to serve as acting assistant surgeon in the U.S. Army for two years. In October 1863, he was appointed assistant professor to Dr. Gross and six months later became chief of Dr. Gross’ surgical clinic at Jefferson Medical College. In November 1865, at the age of only 25 years, he returned to the Philadelphia Hospital, where he was appointed one of the chief surgeons on the retirement of Dr. Gross from that institution. In April of 1866, Maury founded the Summer Course on Venereal and Cutaneous Diseases in the Jefferson Medical College, where he taught until his death.1 Although Maury did not consider himself a dermatologist, his expertise in this emerging field was widely recognized

    Pattern formation of indirect excitons in coupled quantum wells

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    Using a nonlinear Schr\"odinger equation including short-range two-body attraction and three-body repulsion, we investigate the spatial distribution of indirect excitons in semiconductor coupled quantum wells. The results obtained can interpret the experimental phenomenon that annular exciton cloud first contracts then expands when the number of confined excitons is increased in impurity potential well, as observed by Lai \emph{et al.} [Lai etal.et al., Science \textbf{303}, 503 (2004)]. In particular, the model reconciles the patterns of exciton rings reported by Butov \emph{et al.} [Butov etal.et al., Nature \textbf{418}, 751 (2002)]. At higher densities, the model predicts much richer patterns, which could be tested by future experiments.Comment: 5 Revtex4 pages, 3 figure

    UV solar irradiance in observations and the NRLSSI and SATIRE-S models

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    Total solar irradiance and UV spectral solar irradiance have been monitored since 1978 through a succession of space missions. This is accompanied by the development of models aimed at replicating solar irradiance by relating the variability to solar magnetic activity. The NRLSSI and SATIRE-S models provide the most comprehensive reconstructions of total and spectral solar irradiance over the period of satellite observation currently available. There is persistent controversy between the various measurements and models in terms of the wavelength dependence of the variation over the solar cycle, with repercussions on our understanding of the influence of UV solar irradiance variability on the stratosphere. We review the measurement and modelling of UV solar irradiance variability over the period of satellite observation. The SATIRE-S reconstruction is consistent with spectral solar irradiance observations where they are reliable. It is also supported by an independent, empirical reconstruction of UV spectral solar irradiance based on UARS/SUSIM measurements from an earlier study. The weaker solar cycle variability produced by NRLSSI between 300 and 400 nm is not evident in any available record. We show that although the method employed to construct NRLSSI is principally sound, reconstructed solar cycle variability is detrimentally affected by the uncertainty in the SSI observations it draws upon in the derivation. Based on our findings, we recommend, when choosing between the two models, the use of SATIRE-S for climate studies

    The nature of solar brightness variations

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    The solar brightness varies on timescales from minutes to decades. Determining the sources of such variations, often referred to as solar noise, is of importance for multiple reasons: a) it is the background that limits the detection of solar oscillations, b) variability in solar brightness is one of the drivers of the Earth's climate system, c) it is a prototype of stellar variability which is an important limiting factor for the detection of extra-solar planets. Here we show that recent progress in simulations and observations of the Sun makes it finally possible to pinpoint the source of the solar noise. We utilise high-cadence observations from the Solar Dynamic Observatory and the SATIRE model to calculate the magnetically-driven variations of solar brightness. The brightness variations caused by the constantly evolving cellular granulation pattern on the solar surface are computed with the MURAM code. We find that surface magnetic field and granulation can together precisely explain solar noise on timescales from minutes to decades, i.e. ranging over more than six orders of magnitude in the period. This accounts for all timescales that have so far been resolved or covered by irradiance measurements. We demonstrate that no other sources of variability are required to explain the data. Recent measurements of Sun-like stars by CoRoT and Kepler uncovered brightness variations similar to that of the Sun but with much wider variety of patterns. Our finding that solar brightness variations can be replicated in detail with just two well-known sources will greatly simplify future modelling of existing CoRoT and Kepler as well as anticipated TESS and PLATO data.Comment: This is the submitted version of the paper published in Nature Astronom

    Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease.

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    Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe. Molecular dating suggests that T. cruzi is likely to have been an endemic infection of neotropical mammalian fauna for many millions of years. Here we have applied a panel of 49 polymorphic microsatellite markers developed from the online T. cruzi genome to document genetic diversity among 53 isolates belonging to TcIIc, a lineage so far recorded almost exclusively in silvatic transmission cycles but increasingly a potential source of human infection. These data are complemented by parallel analysis of sequence variation in a fragment of the glucose-6-phosphate isomerase gene. New isolates confirm that TcIIc is associated with terrestrial transmission cycles and armadillo reservoir hosts, and demonstrate that TcIIc is far more widespread than previously thought, with a distribution at least from Western Venezuela to the Argentine Chaco. We show that TcIIc is truly a discrete T. cruzi lineage, that it could have an ancient origin and that diversity occurs within the terrestrial niche independently of the host species. We also show that spatial structure among TcIIc isolates from its principal host, the armadillo Dasypus novemcinctus, is greater than that among TcI from Didelphis spp. opossums and link this observation to differences in ecology of their respective niches. Homozygosity in TcIIc populations and some linkage indices indicate the possibility of recombination but cannot yet be effectively discriminated from a high genome-wide frequency of gene conversion. Finally, we suggest that the derived TcIIc population genetic data have a vital role in determining the origin of the epidemiologically important hybrid lineages TcIId and TcIIe

    T-junction ion trap array for two-dimensional ion shuttling, storage and manipulation

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    We demonstrate a two-dimensional 11-zone ion trap array, where individual laser-cooled atomic ions are stored, separated, shuttled, and swapped. The trap geometry consists of two linear rf ion trap sections that are joined at a 90 degree angle to form a T-shaped structure. We shuttle a single ion around the corners of the T-junction and swap the positions of two crystallized ions using voltage sequences designed to accommodate the nontrivial electrical potential near the junction. Full two-dimensional control of multiple ions demonstrated in this system may be crucial for the realization of scalable ion trap quantum computation and the implementation of quantum networks.Comment: 3 pages, 5 figure

    Metastable Dynamics of the Hard-Sphere System

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    The reformulation of the mode-coupling theory (MCT) of the liquid-glass transition which incorporates the element of metastability is applied to the hard-sphere system. It is shown that the glass transition in this system is not a sharp one at the special value of the density or the packing fraction, which is in contrast to the prediction by the conventional MCT. Instead we find that the slowing down of the dynamics occurs over a range of values of the packing fraction. Consequently, the exponents governing the sequence of time relaxations in the intermediate time regime are given as functions of packing fraction with one additional parameter which describes the overall scale of the metastable potential energy for defects in the hard-sphere system. Implications of the present model on the recent experiments on colloidal systems are also discussed.Comment: 21 pages, 5 figures (available upon request), RevTEX3.0, JFI Preprint
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