85 research outputs found
Hydrogen Bond Energies in Carboxylic Acids
A question of interest to the study of the chemisorption of carbon monoxide on iron is whether the carbon is desorbed with the same oxygen to which it was bonded prior to the adsorption. A mixture of C13O and CO18 in the desorbed gas in amounts greater than expected from normal abundance ratios shows that an intermolecular oxygen exchange occurs
Detection of equine herpesvirus-4 and physiological stress patterns in young Thoroughbreds consigned to a South African auction sale
The diagnosis of metachromatic leucodystrophy during life: metachromatic lipids in saliva and cerebrospinal fluid sediments and in the parotid glands
Regulation of skeletal muscle oxidative capacity and insulin signaling by the Mitochondrial Rhomboid Protease PARL
Type 2 diabetes mellitus (T2DM) and aging are characterized by insulin resistance and impaired mitochondrial energetics. In lower organisms, remodeling by the protease pcp1 (PARL ortholog) maintains the function and lifecycle of mitochondria. We examined whether variation in PARL protein content is associated with mitochondrial abnormalities and insulin resistance. PARL mRNA and mitochondrial mass were both reduced in elderly subjects and in subjects with T2DM. Muscle knockdown of PARL in mice resulted in malformed mitochondrial cristae, lower mitochondrial content, decreased PGC1α protein levels, and impaired insulin signaling. Suppression of PARL protein in healthy myotubes lowered mitochondrial mass and insulin-stimulated glycogen synthesis and increased reactive oxygen species production. We propose that lower PARL expression may contribute to the mitochondrial abnormalities seen in aging and T2DM.<br /
THE DIELECTRIC CONSTANT AND CONDUCTANCE OF ION PAIRS; AN EXTENSION OF ONSAGER'S FIELD EFFECT TO RELAXATION OF ION PARIS IN AN ALTERNATING FIELD 1
The importance of the effect of the solvent dielectric constant on ion-pair formation in water at high temperatures and pressures
THE CONDUCTANCE OF TETRA-n-BUTYLAMMONIUM PICRATE IN 50 MOLE% BENZENE-o-DICHLOROBENZENE AND BROMOBENZENE AS A FUNCTION OF TEMPERATURE
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