36 research outputs found

    Bio-optical profile data report coastal transition zone program, R/V Point Sur, June 15-28, 1987

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    Twenty vertical profiles of the bio-optical properties of the ocean were made during a research cruise on the R/V Point Sur, June 15 to 28, 1987, as part of the Coastal Transition Zone Program off Point Arena, California. Extracted chlorophyll values were also measured at some stations to provide calibration data for the in situ fluorometer. This summary provides investigators with an overview of the data collected. The entire data set is available in digital form

    Bio-optical profile data report coastal transition zone program, R/V Thomas Washington, June 24 - July 21, 1988

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    Twenty-three vertical profiles of the bio-optical properties of the ocean were made during a research cruise on the R/V Thomas Washington, June 24 to July 21, 1988, as part of the Coastal Transition Zone Program off Point Arena, California. A summary is given, to provide investigators with an overview of the data collected. The entire data set is available in digital form for interested researchers

    Bio-optical profile data report: Joint Global Ocean Flux Study, Hawaii Ocean Time-Series, HOT-3, R/V Moana Wave, 6-10 January 1989

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    Time-series measurements of the incident surface downwelling irradiance and vertical profiles of the Bio-optical properties of the ocean have been measured during the third cruise of the Hawaii Ocean Time-Series to the ALOHA site, 22 degrees 56.4 minutes N, 157 degrees 54.6 minutes W, north of the island of Oahu, Hawaii, during the period January 6 to 10, 1989. A summary of these data is presented to permit investigators an overview of the data collected. The data are available in digital form for scientific investigators

    Multiple dataset water-quality analyses in the vicinity of an ocean wastewater plume

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    The White's Point ocean outfall is the method of disposal for approximately 374 million gallons of treated wastewater per day from Los Angeles County. The photosynthetic characteristics and particle distributions have well-defined properties that can be exploited to yield information on transport of the plume, mixing dynamics, and resuspension of bottom sediments during periods of bottom current velocity in excess of ca. 0.1 m/s. This plume of particles serves as a conservative tracer, which was studied using a number of sampling platforms and strategies, including underway sawtooth, or 'tow-yo' sampling, moored arrays of instruments, stationary profiling, and now for the first time with remotely-sensed multispectral color imagery. Research in this area previously focused on examination of the plume as it relates to the local current field and transport of particles, and on the resuspension of bottom sediments during periods of increased currents. In addition, Wu et al elucidated techniques for separating the particle signal into photosynthetic and nonphotosynthetic components, based on the beam attenuation to chlorophyll fluorescence ratio. High-frequency time series measurements of the current field and bio-optical characteristics at a site close to the waste diffusers were also collected. These are being analyzed for the spectral characteristics of the longer-timescale variability, in order to predict particle transport through simple meteorological measurements. With the advent of high spectral and spatial resolution imaging spectrometers such as AVIRIS, it is now possible to construct causal relationships between particle distributions and signature of the upwelled radiance from the surface. The availability of a constant and well-characterized source of material lends itself well to models which predict upwelled radiance from the surface. The availability of a constant and well-characterized source of material lends itself well to models which predict upwelled light as a function of particle distributions, photosynthetic pigments, colored dissolved organic material, and detrital and degradation products of photosynthesis. In addition, the spatial coverage provided by the tow-yo sampling device, combined with the profile measurements of the light field, should facilitate the best inverse modeling attempts possible thus far

    Atmospheric correction of AVIRIS data of Monterey Bay contaminated by thin cirrus clouds

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    Point source measurements (e.g. sun photometer data, weather station observations) are often used to constrain radiative transfer models such as MODTRAN/LOWTRAN7 when atmospherically correcting AVIRIS imagery. The basic assumption is that the atmosphere is horizontally homogeneous throughout the entire area. If the target area of interest is isolated a distance away from the point measurement position, the calculated visibility and atmospheric profiles may not be characteristic of the atmosphere over the target. AVIRIS scenes are often rejected when cloud cover exceeds 10%. However, if the cloud cover is determined to be primarily cirrus rather than cumulus, in-water optical properties may still be extracted over open ocean. High altitude cirrus clouds are non-absorbing at 744 nm. If the optical properties of the AVIRIS scene can be determined from the 744 nm band itself, the atmospheric conditions during the overflight may be deduced

    Parameters for the depth of the ocean’s productive layer

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    Here we compare various parameters that are used to define the depth of the ocean’s productive layer, the euphotic zone, during the initiation of the spring phytoplankton bloom in the North Atlantic (47°N/20°W). These are (1) the compensation depth (Zc, where gross photosynthesis balances autotrophic respiration), (2) the depth horizon of 1% of surface photosynthetic active irradiance (Ed(0-,PAR), (3) depth horizon of 1% of surface Ed(488), and (4) the depth of the bottom of the fluorescence maximum. We also use two related parameters, the depth of the mixed layer and the ratio of integral gross production to integral respiration as a scaling factor for a proxy for the critical depth. Over the course of the observational period (25 April - 7 May, 1989), the mixed layer decreased from 162 to 20 m, and Zc decreased from 64 to 35 m. The depth of 1%Ed(0-,PAR) followed the trajectory of Zc, while Ed(488) and the depth of the bottom of the fluorescence maximum were about 10 m deeper, on average. These data support the criterion of the depth of “1%PAR” to describe the productive layer for more productive areas of the ocean. However, 1% of Ed(488) or the bottom of the fluorescence maximum could be used over a broader range of trophic conditions

    SeaWiFS technical report series. Volume 26: Results of the SeaWiFS Data Analysis Round-Robin, July 1994 (DARR-1994)

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    The accurate determination of upper ocean apparent optical properties (AOP's) is essential for the vicarious calibration of the sea-viewing wide field-of-view sensor (SeaWiFS) instrument and the validation of the derived data products. To evaluate the role that data analysis methods have upon values of derived AOP's, the first Data Analysis Round-Robin (DARR-94) workshop was sponsored by the SeaWiFS Project during 21-23 July, 1994. The focus of this intercomparison study was the estimation of the downwelling irradiance spectrum just beneath the sea surface, E(sub d)(0(sup -), lambda); the upwelling nadir radiance just beneath the sea surface, L(sub u)(0(sup -), lambda); and the vertical profile of the diffuse attenuation coefficient spectrum, K(sub d)(z, lambda). In the results reported here, different methodologies from four research groups were applied to an identical set of 10 spectroradiometry casts in order to evaluate the degree to which data analysis methods influence AOP estimation, and whether any general improvements can be made. The overall results of DARR-94 are presented in Chapter 1 and the individual methods of the four groups are presented in Chapters 2-5. The DARR-94 results do not show a clear winner among data analysis methods evaluated. It is apparent, however, that some degree of outlier rejection is required in order to accurately estimate L(sub u)(0(sup -), lambda) or E(sub d)(0(sup -), lambda). Furthermore, the calculation, evaluation and exploitation of confidence intervals for the AOP determinations needs to be explored. That is, the SeaWiFS calibration and validation problem should be recast in statistical terms where the in situ AOP values are statistical estimates with known confidence intervals

    Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

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    BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
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