Impact of phonons on dephasing of individual excitons in deterministic quantum dot microlenses

Optimized light-matter coupling in semiconductor nanostructures is a key to understand their optical properties and can be enabled by advanced fabrication techniques. Using in-situ electron beam lithography combined with a low-temperature cathodoluminescence imaging, we deterministically fabricate microlenses above selected InAs quantum dots (QDs) achieving their efficient coupling to the external light field. This enables to perform four-wave mixing micro-spectroscopy of single QD excitons, revealing the exciton population and coherence dynamics. We infer the temperature dependence of the dephasing in order to address the impact of phonons on the decoherence of confined excitons. The loss of the coherence over the first picoseconds is associated with the emission of a phonon wave packet, also governing the phonon background in photoluminescence (PL) spectra. Using theory based on the independent boson model, we consistently explain the initial coherence decay, the zero-phonon line fraction, and the lineshape of the phonon-assisted PL using realistic quantum dot geometries

The Structure and Evolution of Magnetized Cloud Cores in a Zero--Density Background

Molecular-line observations of star-forming cloud cores indicate that they are not the flattened structures traditionally considered by theory. Rather, they are elongated, perhaps in the direction of their internal magnetic field. We are thus motivated to consider the structure and evolution of axisymmetric, magnetized clouds that start from a variety of initial states, both flattened (oblate) and elongated (prolate). We devise a new technique, dubbed the $q$-method, that allows us to construct magnetostatic equilibria of any specified shape. We find, in agreement with previous authors, that the field lines in oblate clouds bend inward. However, those in prolate clouds bow outward, confining the structures through magnetic tension. We next follow the quasi-static evolution of these clouds via ambipolar diffusion, under the assumption of constant core mass. An oblate cloud either relaxes to a magnetically force-free sphere or, if sufficiently massive, flattens along its polar axis as its central density runs away. A prolate cloud always relaxes to a sphere of modest central density. We finally consider the evolution of an initially spherical cloud subject to the tidal gravity of neighboring bodies. Although the structure constricts equatorially, it also shortens along the pole, so that it ultimately flattens on the way to collapse. In summary, none of our initial states can evolve to the point of collapse while maintaining an elongated shape. We speculate that this situation will change once we allow the cloud to gain mass from its environment.Comment: 19 pages, plus 20 postscript figures. Accepted by Ap

Zooming towards the Event Horizon - mm-VLBI today and tomorrow

Global VLBI imaging at millimeter and sub-millimeter wavelength overcomes the opacity barrier of synchrotron self-absorption in AGN and opens the direct view into sub-pc scale regions not accessible before. Since AGN variability is more pronounced at short millimeter wavelength, mm-VLBI can reveal structural changes in very early stages after outbursts. When combined with observations at longer wavelength, global 3mm and 1mm VLBI adds very detailed information. This helps to determine fundamental physical properties at the jet base, and in the vicinity of super-massive black holes at the center of AGN. Here we present new results from multi-frequency mm-VLBI imaging of OJ287 during a major outburst. We also report on a successful 1.3mm VLBI experiment with the APEX telescope in Chile. This observation sets a new record in angular resolution. It also opens the path towards future mm-VLBI with ALMA, which aims at the mapping of the black hole event horizon in nearby galaxies, and the study of the roots of jets in AGN.Comment: 6 pages, to appear in 11th European VLBI Network Symposium, ed. P. Charlot et al., Bordeaux (France), October 9-12, 201

EVN+MERLIN Observations of Radio-Intermediate Quasars: Evidence for Boosted Radio-Weak Quasars

We present VLBI (EVN+MERLIN) observations of a sample of three low-redshift radio-intermediate PG quasars (RIQ) with flat and variable radio spectrum (III Zw 2, PG 1309+355, PG 2209+184). Their radio-to-optical flux ratio (R) is slightly lower than the average R for steep-spectrum quasars, but their radio spectral properties are those of core-dominated quasars. It was proposed previously that these sources might be relativistically boosted jets in radio-weak quasars. Our VLBI observations now indeed confirm the presence of a high brightness temperature core in all three of these objects --- two of them have lower limits on T_B well in excess of 10^10 Kelvin. Moreover, we find no ``missing-flux'' which means that basically all the flux of these quasars is concentrated in the compact radio core. As the total radio flux is already at the low end for radio-loud quasars, we can place a strong limit on the presence of any extended emission. This limit is consistent with the extended emission in radio-weak quasars, but excludes that the flat-spectrum RIQ reside in typical radio-loud quasars. The observations therefore strongly support the idea that relativistic jets are present in radio-weak quasars and hence that radio-loud and radio-weak quasars have very similar central engines.Comment: ApJ Letters, accepted for publication, 7 pages, 4 PS Figures, AASTeX, also available at http://www.astro.umd.edu/~hfalcke/publications.html#riqvlb

Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis

Cassette dosing of compounds for preclinical drug plasma pharmacokinetic analysis has been shown to be a powerful strategy within the pharmaceutical industry for increasing throughput while decreasing the number of animals used. Presented here for the first time is data on the application of a cassette dosing strategy for label-free tissue distribution studies. The aim of the study was to image the spatial distribution of eight nonproprietary drugs (haloperidol, bufuralol, midazolam, clozapine, terfenadine, erlotinib, olanzapine, and moxifloxacin) in multiple tissues after oral and intravenous cassette dosing (four compounds per dose route). An array of mass spectrometry imaging technologies, including matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI MSI), liquid extraction surface analysis tandem mass spectrometry (LESA-MS/MS), and desorption electrospray ionization mass spectrometry (DESI-MS) was used. Tissue analysis following intravenous and oral administration of discretely and cassette-dosed compounds demonstrated similar relative abundances across a range of tissues indicating that a cassette dosing approach was applicable. MALDI MSI was unsuccessful in detecting all of the target compounds; therefore, DESI MSI, a complementary mass spectrometry imaging technique, was used to detect additional target compounds. In addition, by adapting technology used for tissue profiling (LESA-MS/MS) low spatial resolution mass spectrometry imaging (∼1 mm) was possible for all targets across all tissues. This study exemplifies the power of multiplatform MSI analysis within a pharmaceutical research and development (R&D) environment. Furthermore, we have illustrated that the cassette dosing approach can be readily applied to provide combined, label-free pharmacokinetic and drug distribution data at an early stage of the drug discovery/development process while minimizing animal usage

Irradiation of the secondary star in X-ray Nova Scorpii 1994 (=GRO J1655--40)

We have obtained intermediate resolution optical spectra of the black-hole candidate Nova Sco 1994 in June 1996, when the source was in an X-ray/optical active state (R~15.05). We measure the radial velocity curve of the secondary star and obtain a semi-amplitude of 279+/-10 km/s; a value which is 30 per cent larger than the value obtained when the source is in quiescence. Our large value for K_2 is consistent with 60 +9,-7 per cent of the secondary star's surface being heated; compared to 35 per cent, which is what one would expect if only the inner face of the secondary star were irradiated. Effects such as irradiation-induced flows on the secondary star may be important in explaining the observed large value for K_2.Comment: 5 pages, 2 figures, accepted by MNRA

Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration

Arf4 is proposed to be a critical regulator of membrane protein trafficking in early secretory pathway. More recently, Arf4 was also implicated in regulating ciliary trafficking, however, this has not been comprehensively tested in vivo. To directly address Arf4\u27s role in ciliary transport, we deleted Arf4 specifically in either rod photoreceptor cells, kidney, or globally during the early postnatal period. Arf4 deletion in photoreceptors did not cause protein mislocalization or retinal degeneration, as expected if Arf4 played a role in protein transport to the ciliary outer segment. Likewise, Arf4 deletion in kidney did not cause cystic disease, as expected if Arf4 were involved in general ciliary trafficking. In contrast, global Arf4 deletion in the early postnatal period resulted in growth restriction, severe pancreatic degeneration and early death. These findings are consistent with Arf4 playing a critical role in endomembrane trafficking, particularly in the pancreas, but not in ciliary function

Genetic link between renal birth defects and congenital heart disease

Structural birth defects in the kidney and urinary tract are observed in 0.5% of live births and are a major cause of end-stage renal disease, but their genetic aetiology is not well understood. Here we analyse 135 lines of mice identified in large-scale mouse mutagenesis screen and show that 29% of mutations causing congenital heart disease (CHD) also cause renal anomalies. The renal anomalies included duplex and multiplex kidneys, renal agenesis, hydronephrosis and cystic kidney disease. To assess the clinical relevance of these findings, we examined patients with CHD and observed a 30% co-occurrence of renal anomalies of a similar spectrum. Together, these findings demonstrate a common shared genetic aetiology for CHD and renal anomalies, indicating that CHD patients are at increased risk for complications from renal anomalies. This collection of mutant mouse models provides a resource for further studies to elucidate the developmental link between renal anomalies and CHD

Temperature-stable operation of a quantum dot semiconductor disk laser

This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Appl. Phys. Lett. 93, 051104 (2008) and may be found at https://doi.org/10.1063/1.2968137.We demonstrate temperature-independent output characteristics of an optically pumped semiconductor disk laser (SDL) based on quantum dots (QDs) grown in the Stranski-Krastanow regime. The gain structure consists of a stack of 7×3 QD layers, each threefold group being located at an optical antinode position. The SDL emits at 1210nm independent of the pump power density. Threshold and differential efficiency do not dependent on heat sink temperature. Continuous-wave operation close to 300mW output power is achieved using the ground-state transition of the InGaAs QDs.DFG, 43659573, SFB 787: Halbleiter - Nanophotonik: Materialien, Modelle, BauelementeEC/FP6/016769/EU/Nano-Photonics Materials and Technologies for Multicolor High-Power Sources/NATA