2,637 research outputs found
Early evolution of electron cyclotron driven current during suppression of tearing modes in a circular tokamak
When electron cyclotron (EC) driven current is first applied to the inside of
a magnetic island, the current spreads throughout the island and after a short
period achieves a steady level. Using a two equation fluid model for the EC
current that allows us to examine this early evolution in detail, we analyze
high-resolution simulations of a 2/1 classical tearing mode in a low-beta large
aspect-ratio circular tokamak. These simulations use a nonlinear 3D reduced-MHD
fluid model and the JOREK code. During the initial period where the EC driven
current grows and spreads throughout the magnetic island, it is not a function
of the magnetic flux. However, once it has reached a steady-state, it should be
a flux function. We demonstrate numerically that if sufficiently resolved
toroidally, the steady-state EC driven current becomes approximately a flux
function. We discuss the physics of this early period of EC evolution and its
impact on the size of the magnetic island.Comment: 12 pages, 7 figure
Isotope Effect in the Superfluid Density of HTS Cuprates: Stripes, Pseudogap and Impurities
Underdoped cuprates exhibit a normal-state pseudogap, and their spins and
doped carriers tend to spatially separate into 1- or 2-D stripes. Some view
these as central to superconductivity, others as peripheral and merely
competing. Using LaSrCuZnO we show that an oxygen
isotope effect in and in the superfluid density can be used to
distinguish between the roles of stripes and pseudogap and also to detect the
presence of impurity scattering. We conclude that stripes and pseudogap are
distinct, and both compete and coexist with superconductivity.Comment: Revised submission to PRL with added appendix on a possible isotope
effect in the effective mass, 4 pages, 3 figure
Effects of calorie restriction and IGF-1 receptor blockade on the progression of 22Rv1 prostate cancer xenografts.
Calorie restriction (CR) inhibits prostate cancer progression, partially through modulation of the IGF axis. IGF-1 receptor (IGF-1R) blockade reduces prostate cancer xenograft growth. We hypothesized that combining calorie restriction with IGF-1R blockade would have an additive effect on prostate cancer growth. Severe combined immunodeficient mice were subcutaneously injected with 22Rv1 cells and randomized to: (1) Ad libitum feeding/intraperitoneal saline (Ad-lib); (2) Ad-lib/20 mg/kg twice weekly, intraperitoneal ganitumab [anti-IGF-1R antibody (Ad-lib/Ab)]; (3) 40% calorie restriction/intraperitoneal saline (CR); (4) CR/ intraperitoneal ganitumab, (CR/Ab). CR and ganitumab treatment were initiated one week after tumor injection. Euthanasia occurred 19 days post treatment. Results showed that CR alone decreased final tumor weight, plasma insulin and IGF-1 levels, and increased apoptosis. Ganitumab therapy alone reduced tumor growth but had no effect on final tumor weight. The combination therapy (CR/Ab) further decreased final tumor weight and proliferation, increased apoptosis in comparison to the Ad-lib group, and lowered plasma insulin levels relative to the Ad-lib and Ad-lib/Ab groups. Tumor AKT activation directly correlated with plasma IGF-1 levels. In conclusion, whereas ganitumab therapy modestly affected 22Rv1 tumor growth, combining IGF-1R blockade with calorie restriction resulted in a significant decrease in final tumor weight and improved metabolic profile
Pairing in Cu-O Models: Clues of Joint Electron-Phonon and Electron-Electron Interactions
We discuss a many-electron Hamiltonian with Hubbard-like repulsive
interaction and linear coupling to the phonon branches, having the Cu-O plane
of the superconducting cuprates as a paradigm. A canonical transformation
extracts an effective two-body problem from the many-body theory. As a
prototype system we study the \cu cluster, which yields electronic pairing in
the Hubbard model; moreover, a standard treatment of the Jahn-Teller effect
predicts distortions that destroy electronic pairing. Remarkably, calculations
that keep all the electronic spectrum into account show that vibrations are
likely to be synergic with electronic pairing, if the coupling to
half-breathing modes predominates, as experiments suggest.Comment: 4 pages, 3 figures, accepted by Phys. Rev.
Oxygen-isotope effect on the superconducting gap in the cuprate superconductor Y_{1-x}Pr_xBa_2Cu_3O_{7-\delta}
The oxygen-isotope (^{16}O/^{18}O) effect (OIE) on the zero-temperature
superconducting energy gap \Delta_0 was studied for a series of
Y_{1-x}Pr_xBa_2Cu_3O_{7-\delta} samples (0.0\leq x\leq0.45). The OIE on
\Delta_0 was found to scale with the one on the superconducting transition
temperature. These experimental results are in quantitative agreement with
predictions from a polaronic model for cuprate high-temperature superconductors
and rule out approaches based on purely electronic mechanisms.Comment: 5 pages, 3 figure
Isotope effects in underdoped cuprate superconductors: a quantum phenomenon
We show that the unusual doping dependence of the isotope effects on
transition temperature and zero temperature in - plane penetration depth
naturally follows from the doping driven 3D-2D crossover, the 2D quantum
superconductor to insulator transition (QSI) in the underdoped limit and the
change of the relative doping concentration upon isotope substitution. Close to
the QSI transition both, the isotope coefficient of transition temperature and
penetration depth approach the coefficient of the relative dopant
concentration, and its divergence sets the scale. These predictions are fully
consistent with the experimental data and imply that close to the underdoped
limit the unusual isotope effect on transition temperature and penetration
depth uncovers critical phenomena associated with the quantum superconductor to
insulator transition in two dimensions.Comment: 6 pages, 3 figure
Measuring kinetic coefficients by molecular dynamics simulation of zone melting
Molecular dynamics simulations are performed to measure the kinetic
coefficient at the solid-liquid interface in pure gold. Results are obtained
for the (111), (100) and (110) orientations. Both Au(100) and Au(110) are in
reasonable agreement with the law proposed for collision-limited growth. For
Au(111), stacking fault domains form, as first reported by Burke, Broughton and
Gilmer [J. Chem. Phys. {\bf 89}, 1030 (1988)]. The consequence on the kinetics
of this interface is dramatic: the measured kinetic coefficient is three times
smaller than that predicted by collision-limited growth. Finally,
crystallization and melting are found to be always asymmetrical but here again
the effect is much more pronounced for the (111) orientation.Comment: 8 pages, 9 figures (for fig. 8 : [email protected]). Accepted for
publication in Phys. Rev.
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