100 research outputs found
Nonlinear dielectric effect of dipolar fluids
The nonlinear dielectric effect for dipolar fluids is studied within the
framework of the mean spherical approximation (MSA) of hard core dipolar Yukawa
fluids. Based on earlier results for the electric field dependence of the
polarization our analytical results show so-called normal saturation effects
which are in good agreement with corresponding NVT ensemble Monte Carlo
simulation data. The linear and the nonlinear dielectric permittivities
obtained from MC simulations are determined from the fluctuations of the total
dipole moment of the system in the absence of an applied electric field. We
compare the MSA based theoretical results with the corresponding Langevin and
Debye-Weiss behaviors.Comment: 10 pages including 4 figure
Nucleon to Delta Weak Excitation Amplitudes in the Non-relativistic Quark Model
We investigate the nucleon to Delta(1232) vector and axial vector amplitudes
in the non-relativistic quark model of the Isgur-Karl variety. A particular
interest is to investigate the SU(6) symmetry breaking, due to color hyperfine
interaction. We compare the theoretical estimates to recent experimental
investigation of the Adler amplitudes by neutrino scattering.Comment: \documentstyle[aps]{revtex}, 21pages; 11 postscript figures. Accepted
for publication by Phys. Rev.
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Faulty Adaptation to Repeated Face-Name Associative Pairs in Mild Cognitive Impairment is Predictive of Cognitive Decline
ObjectiveWe examined BOLD (Blood-Oxygen-Level Dependent) activity reduction upon stimuli repetition of face-name pairs in older adults with amnestic (aMCI) and non-amnestic (naMCI) mild cognitive impairment diagnosed using a comprehensive actuarial method, and relationships between activity reduction and behavioral indices.MethodTwenty-nine cognitively healthy older adults (CHs) and 20 with MCI (n = 12 aMCI; n = 8 naMCI) underwent functional MRI event-related imaging, a comprehensive neuropsychological battery, and 1-year follow-up exam. During scanning, participants were shown face-name pairs 1-3 times and administered a post-scan recognition task.ResultsThe MCI group demonstrated less activity reduction upon repetition of face-name pairs within the MTL and other regions compared to CHs. Less activity reduction was associated with poorer Time 1 neuropsychological performance for the CH group and poorer post-scan recognition performance for the MCI group. Less activity reduction was related to poorer neuropsychological performance at Time 2 in the MCI group. Within MCIs, those with aMCI demonstrated less activity reduction upon repetition of face-name pairs than those with naMCI.ConclusionsDistinct patterns of brain activity were identified in the MCI group compared to CHs, and aMCI compared to naMCI. Activated regions were not restricted to traditional memory circuitry, implicating a wider network of regions involved in the encoding of associative tasks. Findings add support to the hypothesis that lack of reduced BOLD activity reflects "faulty adaptation" to repeated stimuli and that reduction in activity represents successful encoding processes. They also provide further support for use of the face-name paradigm as a marker of prodromal Alzheimer's disease, and method to distinguish between MCI subtypes
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