11,486 research outputs found

    The diversity of a distributed genome in bacterial populations

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    The distributed genome hypothesis states that the set of genes in a population of bacteria is distributed over all individuals that belong to the specific taxon. It implies that certain genes can be gained and lost from generation to generation. We use the random genealogy given by a Kingman coalescent in order to superimpose events of gene gain and loss along ancestral lines. Gene gains occur at a constant rate along ancestral lines. We assume that gained genes have never been present in the population before. Gene losses occur at a rate proportional to the number of genes present along the ancestral line. In this infinitely many genes model we derive moments for several statistics within a sample: the average number of genes per individual, the average number of genes differing between individuals, the number of incongruent pairs of genes, the total number of different genes in the sample and the gene frequency spectrum. We demonstrate that the model gives a reasonable fit with gene frequency data from marine cyanobacteria.Comment: Published in at http://dx.doi.org/10.1214/09-AAP657 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org

    Contour surveying system Patent

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    Describing device for surveying contour of surface using X-Y plotter and traveling transduce

    Static and unsteady pressure measurements on a 50 degree clipped delta wing at M = 0.9

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    Pressures were measured with Freon as the test medium. Data taken at M = 0.9 is presented for static and oscillatory deflections of the trailing edge control surface and for the wing in pitch. Comparisons of the static measured data are made with results computed using the Bailey-Ballhaus small disturbance code

    Steady and unsteady transonic pressure measurements on a clipped delta wing for pitching and control-surface oscillations

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    Steady and unsteady pressures were measured on a clipped delta wing with a 6-percent circular-arc airfoil section and a leading-edge sweep angle of 50.40 deg. The model was oscillated in pitch and had an oscillating trailing-edge control surface. Measurements were concentrated over a Mach number range from 0.88 to 0.94; less extensive measurements were made at Mach numbers of 0.40, 0.96, and 1.12. The Reynolds number based on mean chord was approximately 10 x 10 to the 6th power. The interaction of wing or control-surface deflection with the formation of shock waves and with a leading-edge vortex generated complex pressure distributions that were sensitive to frequency and to small changes in Mach number at transonic speeds

    Campylobacter jejuni colonization promotes the translocation of Escherichia coli to extra-intestinal organs and disturbs the short-chain fatty acids profiles in the chicken gut

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    For a long time Campylobacter was only considered as a commensal microorganism in avian hosts restricted to the ceca, without any pathogenic features. The precise reasons for the symptomless chicken carriers are still unknown, but investigations of the gastrointestinal ecology of broiler chickens may improve our understanding of the microbial interactions with the host. Therefore, the current studies were conducted to investigate the effects of Campylobacter jejuni colonization on Escherichia coli translocation and on the metabolic end products (short-chain fatty acids, SCFAs). Following oral infection of 14 day old broiler chickens with 1 × 108 CFU of Campylobacter jejuni NCTC 12744 in two independent animal trials, it was found that C. jejuni heavily colonized the intestine and disseminate to extra-intestinal organs. Moreover, in both animal trials, the findings revealed that C. jejuni promoted the translocation of E. coli with a higher number encountered in the spleen and liver at 14 days post infection (dpi). In addition, Campylobacter affected the microbial fermentation in the gastrointestinal tract of broilers by reducing the amount of propionate, isovalerate, and isobutyrate in the cecal digesta of the infected birds at 2 dpi and, at 7 and 14 dpi, butyrate, isobutyrate, and isovalerate were also decreased. However, in the jejunum, the C. jejuni infection lowered only butyrate concentrations at 14 dpi. These data indicated that C. jejuni may utilize SCFAs as carbon sources to promote its colonization in the chicken gut, suggesting that Campylobacter cannot only alter gut colonization dynamics but might also influence physiological processes due to altered microbial metabolite profiles. Finally, the results demonstrated that C. jejuni can cross the intestinal epithelial barrier and facilitates the translocation of Campylobacter itself as well as of other enteric microorganisms such as E. coli to extra-intestinal organs of infected birds. Altogether, our findings suggest that the Campylobacter carrier state in chicken is characterised by multiple changes in the intestinal barrier function, which supports multiplication and survival within the host

    A Model Township Comprehensive Plan.

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    Magnetic heat conductivity in CaCu2O3\rm\bf CaCu_2O_3: linear temperature dependence

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    We present experimental results for the thermal conductivity κ\kappa of the pseudo 2-leg ladder material CaCu2O3\rm CaCu_2O_3. The strong buckling of the ladder rungs renders this material a good approximation to a S=1/2S=1/2 Heisenberg-chain. Despite a strong suppression of the thermal conductivity of this material in all crystal directions due to inherent disorder, we find a dominant magnetic contribution κmag\kappa_\mathrm{mag} along the chain direction. κmag\kappa_\mathrm{mag} is \textit{linear} in temperature, resembling the low-temperature limit of the thermal Drude weight DthD_\mathrm{th} of the S=1/2S=1/2 Heisenberg chain. The comparison of κmag\kappa_\mathrm{mag} and DthD_\mathrm{th} yields a magnetic mean free path of lmag≈22±5l_\mathrm{mag}\approx 22 \pm 5 \AA, in good agreement with magnetic measurements.Comment: appears in PR

    JPL preferred parts list: Reliable electronic components

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    The JPL Preferred Parts List was prepared to provide a basis for selection of electronic parts for JPL spacecraft programs. Supporting tests for the listed parts were designed to comply with specific spacecraft environmental requirements. The list tabulates the electronic, magnetic, and electromechanical parts applicable to all JPL electronic equipment wherein reliability is a major concern. The parts listed are revelant to equipment supplied by subcontractors as well as fabricated at the laboratory
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